Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRAG1
  • Mouse genes Prag1
  • Rat genes Prag1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prag1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	PRAG1	IDA		Human	PMID:29079850
Molecular Function	GO:0042802	identical protein binding	Prag1	IMP		Rat	PMID:29503074|RGD:13514079
Molecular Function	GO:0005515	protein binding	PRAG1	IPI	UniProtKB:Q9H792	Human	PMID:29079850
Molecular Function	GO:0005515	protein binding	Prag1	IPI	UniProtKB:P46531	Mouse	MGI:MGI:5588600|PMID:25038227
Molecular Function	GO:0005515	protein binding	Prag1	IPI	UniProtKB:Q5HZE6	Rat	PMID:16481321|RGD:11555369
Molecular Function	GO:0005515	protein binding	Prag1	IPI	UniProtKB:P32577	Rat	PMID:21873224|RGD:11556156
Molecular Function	GO:0005515	protein binding	Prag1	IPI	UniProtKB:P32577	Rat	PMID:27116701|RGD:13514074
Cellular Component	GO:0005737	cytoplasm	Prag1	IDA		Rat	PMID:21873224|RGD:11556156
Cellular Component	GO:0005737	cytoplasm	Prag1	IDA		Rat	PMID:27116701|RGD:13514074
Cellular Component	GO:0005925	focal adhesion	PRAG1	IDA		Human	PMID:27116701
Cellular Component	GO:0005925	focal adhesion	Prag1	IDA		Rat	PMID:27116701|RGD:13514074
Cellular Component	GO:0005634	nucleus	Prag1	IDA		Mouse	MGI:MGI:5588600|PMID:25038227
Biological Process	GO:0016477	cell migration	PRAG1	IMP		Human	PMID:29079850
Biological Process	GO:0010977	negative regulation of neuron projection development	Prag1	IMP		Rat	PMID:16481321|RGD:11555369
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	Prag1	IMP		Rat	PMID:16481321|RGD:11555369
Biological Process	GO:2000145	regulation of cell motility	Prag1	IMP		Rat	PMID:27116701|RGD:13514074
Biological Process	GO:0008360	regulation of cell shape	Prag1	IMP		Rat	PMID:27116701|RGD:13514074
Biological Process	GO:0008593	regulation of Notch signaling pathway	Prag1	IMP		Mouse	MGI:MGI:5588600|PMID:25038227

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern