Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRAMEF1,PRAMEF10,PRAMEF11,PRAMEF12,PRAMEF13,PRAMEF15,PRAMEF17,PRAMEF18,PRAMEF19,PRAMEF2,PRAMEF20,PRAMEF25,PRAMEF26,PRAMEF27,PRAMEF33,PRAMEF4,PRAMEF5,PRAMEF6,PRAMEF7,PRAMEF8,PRAMEF9
  • Mouse genes Pramel44
  • Rat genes LOC100363333,Pramef20-ps2,Pramef8-ps2,RGD1561226,RGD1561699,RGD1562932
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pramel44

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	PRAMEF9	IDA		Human	PMID:26138980
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	PRAMEF6	IDA		Human	PMID:26138980
Cellular Component	GO:0031462	Cul2-RING ubiquitin ligase complex	PRAMEF9	IDA		Human	PMID:26138980
Cellular Component	GO:0031462	Cul2-RING ubiquitin ligase complex	PRAMEF6	IDA		Human	PMID:26138980
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PRAMEF9	IDA		Human	PMID:26138980
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PRAMEF6	IDA		Human	PMID:26138980

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern