Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Prdm1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PRDM1
- Mouse genes Prdm1
- Rat genes Prdm1
- Zfish genes prdm1a,prdm1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prdm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	prdm1a	IDA		Zfish	PMID:18535625
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	PRDM1	IDA		Human	PMID:1851123
Molecular Function	GO:1990226	histone methyltransferase binding	Prdm1	IPI	UniProtKB:Q8CIG8	Mouse	PMID:16699504
Molecular Function	GO:1990841	promoter-specific chromatin binding	Prdm1	IDA		Mouse	MGI:MGI:5779429\|PMID:27102484
Molecular Function	GO:0005515	protein binding	PRDM1	IPI	UniProtKB:O75925	Human	PMID:22555612
Molecular Function	GO:0005515	protein binding	PRDM1	IPI	UniProtKB:O00257\|UniProtKB:O75925\|UniProtKB:O75928\|UniProtKB:P29590\|UniProtKB:P78317\|UniProtKB:Q8N2W9\|UniProtKB:Q9Y6X2	Human	PMID:28842558
Molecular Function	GO:0005515	protein binding	PRDM1	IPI	UniProtKB:Q86U70	Human	PMID:32417234
Molecular Function	GO:0005515	protein binding	Prdm1	IPI	UniProtKB:P63165	Mouse	MGI:MGI:5287918\|PMID:21722636
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	PRDM1	IDA		Human	PMID:1851123
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	PRDM1	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	PRDM1	IDA		Human	PMID:21421998
Cellular Component	GO:0005737	cytoplasm	Prdm1	IDA		Mouse	PMID:16699504
Cellular Component	GO:0005730	nucleolus	PRDM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PRDM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PRDM1	IDA		Human	PMID:28842558
Cellular Component	GO:0005634	nucleus	Prdm1	IDA		Mouse	PMID:16699504
Cellular Component	GO:0005634	nucleus	Prdm1	IDA		Mouse	PMID:16901790
Biological Process	GO:0035904	aorta development	Prdm1	IMP		Mouse	PMID:25807483
Biological Process	GO:0048844	artery morphogenesis	Prdm1	IGI	MGI:MGI:98493	Mouse	PMID:24821700
Biological Process	GO:0048844	artery morphogenesis	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:24821700
Biological Process	GO:0048844	artery morphogenesis	Prdm1	IMP	MGI:MGI:3605621	Mouse	PMID:24821700
Biological Process	GO:0003279	cardiac septum development	Prdm1	IMP		Mouse	PMID:25807483
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	prdm1a	IMP	ZFIN:ZDB-GENO-111021-1	Zfish	PMID:21931719
Biological Process	GO:0045165	cell fate commitment	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:15750184
Biological Process	GO:0045165	cell fate commitment	Prdm1	IMP	MGI:MGI:3586884	Mouse	PMID:15937476
Biological Process	GO:0060976	coronary vasculature development	Prdm1	IMP		Mouse	PMID:25807483
Biological Process	GO:0048066	developmental pigmentation	prdm1a	IMP	ZFIN:ZDB-GENO-980202-1090	Zfish	PMID:9007256
Biological Process	GO:0000578	embryonic axis specification	prdm1a	IMP	ZFIN:ZDB-MRPHLNO-050221-1	Zfish	PMID:15623803
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	prdm1a	IMP	ZFIN:ZDB-GENO-080923-9	Zfish	PMID:23109401
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	prdm1a	IMP	ZFIN:ZDB-MRPHLNO-050221-1	Zfish	PMID:23109401
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	prdm1a	IGI	ZFIN:ZDB-MRPHLNO-050221-1,ZFIN:ZDB-MRPHLNO-130225-2	Zfish	PMID:23109401
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	prdm1a	IGI	ZFIN:ZDB-MRPHLNO-050221-1,ZFIN:ZDB-MRPHLNO-130225-4	Zfish	PMID:23109401
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	prdm1a	IGI	ZFIN:ZDB-GENO-131209-1	Zfish	PMID:23109401
Biological Process	GO:0035118	embryonic pectoral fin morphogenesis	prdm1a	IMP	ZFIN:ZDB-MRPHLNO-050221-1	Zfish	PMID:16790478
Biological Process	GO:0001892	embryonic placenta development	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:15750184
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	prdm1a	IGI	ZFIN:ZDB-GENO-131209-1	Zfish	PMID:23109401
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	prdm1a	IGI	ZFIN:ZDB-MRPHLNO-050221-1,ZFIN:ZDB-MRPHLNO-130225-4	Zfish	PMID:23109401
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	prdm1a	IGI	ZFIN:ZDB-GENO-150821-4	Zfish	PMID:25810090
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	prdm1a	IGI	ZFIN:ZDB-MRPHLNO-050221-1,ZFIN:ZDB-MRPHLNO-130225-2	Zfish	PMID:23109401
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	prdm1a	IMP	ZFIN:ZDB-GENO-080923-9	Zfish	PMID:25810090
Biological Process	GO:0042462	eye photoreceptor cell development	Prdm1	IMP	MGI:MGI:3605621,MGI:MGI:4881674	Mouse	PMID:20463215
Biological Process	GO:0042462	eye photoreceptor cell development	Prdm1	IMP	MGI:MGI:3605621,MGI:MGI:3608904	Mouse	PMID:20463215
Biological Process	GO:0033333	fin development	prdm1a	IMP		Zfish	PMID:9007245
Biological Process	GO:0010467	gene expression	Prdm1	IDA		Mouse	PMID:16699504
Biological Process	GO:0007281	germ cell development	Prdm1	IGI	MGI:MGI:1890546	Mouse	PMID:19578360
Biological Process	GO:0003170	heart valve development	Prdm1	IMP		Mouse	PMID:25807483
Biological Process	GO:0001701	in utero embryonic development	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:15750184
Biological Process	GO:0060576	intestinal epithelial cell development	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:21670299
Biological Process	GO:0060576	intestinal epithelial cell development	Prdm1	IMP	MGI:MGI:3605621	Mouse	PMID:21670299
Biological Process	GO:0001822	kidney development	Prdm1	IMP	MGI:MGI:5446157	Mouse	PMID:27002738
Biological Process	GO:0001893	maternal placenta development	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:15750184
Biological Process	GO:0001763	morphogenesis of a branching structure	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:24821700
Biological Process	GO:0001763	morphogenesis of a branching structure	Prdm1	IMP	MGI:MGI:3605621	Mouse	PMID:24821700
Biological Process	GO:0007521	muscle cell fate determination	prdm1a	IMP	ZFIN:ZDB-GENO-980202-1090	Zfish	PMID:14702044
Biological Process	GO:0010629	negative regulation of gene expression	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:21670299
Biological Process	GO:0010629	negative regulation of gene expression	Prdm1	IMP	MGI:MGI:3605621	Mouse	PMID:21670299
Biological Process	GO:0010629	negative regulation of gene expression	prdm1a	IMP	ZFIN:ZDB-GENO-071127-7	Zfish	PMID:18535625
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PRDM1	IDA		Human	PMID:1851123
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Prdm1	IDA		Mouse	PMID:20463215
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	prdm1a	IDA		Zfish	PMID:18535625
Biological Process	GO:0014032	neural crest cell development	prdm1a	IMP	ZFIN:ZDB-GENO-980621-1	Zfish	PMID:10457007
Biological Process	GO:0014033	neural crest cell differentiation	prdm1a	IMP	ZFIN:ZDB-GENO-080923-9	Zfish	PMID:20836130
Biological Process	GO:0035138	pectoral fin morphogenesis	prdm1a	IMP	ZFIN:ZDB-MRPHLNO-050429-1	Zfish	PMID:16949569
Biological Process	GO:0018216	peptidyl-arginine methylation	Prdm1	IDA		Mouse	PMID:16699504
Biological Process	GO:0060037	pharyngeal system development	prdm1a	IMP	ZFIN:ZDB-GENO-080923-9	Zfish	PMID:19777590
Biological Process	GO:0010628	positive regulation of gene expression	Prdm1	IDA		Mouse	PMID:18622394
Biological Process	GO:0045666	positive regulation of neuron differentiation	prdm1a	IMP	ZFIN:ZDB-MRPHLNO-050429-1	Zfish	PMID:15680355
Biological Process	GO:0045666	positive regulation of neuron differentiation	prdm1a	IMP	ZFIN:ZDB-GENO-080923-9	Zfish	PMID:20836130
Biological Process	GO:0045666	positive regulation of neuron differentiation	prdm1a	IMP	ZFIN:ZDB-GENO-980621-1	Zfish	PMID:15680355
Biological Process	GO:0045666	positive regulation of neuron differentiation	prdm1a	IMP	ZFIN:ZDB-GENO-980202-1090	Zfish	PMID:15458650
Biological Process	GO:0051155	positive regulation of striated muscle cell differentiation	prdm1a	IMP	ZFIN:ZDB-GENO-071127-7	Zfish	PMID:18535625
Biological Process	GO:0009791	post-embryonic development	Prdm1	IMP	MGI:MGI:3605621	Mouse	PMID:21670299
Biological Process	GO:0009791	post-embryonic development	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:21670299
Biological Process	GO:0042127	regulation of cell population proliferation	Prdm1	IMP	MGI:MGI:3605483	Mouse	PMID:24821700
Biological Process	GO:0042127	regulation of cell population proliferation	Prdm1	IMP	MGI:MGI:3605621	Mouse	PMID:24821700
Biological Process	GO:0033082	regulation of extrathymic T cell differentiation	Prdm1	IMP		Mouse	MGI:MGI:5779429\|PMID:27102484
Biological Process	GO:0032823	regulation of natural killer cell differentiation	Prdm1	IMP		Mouse	MGI:MGI:5779429\|PMID:27102484
Biological Process	GO:0051136	regulation of NK T cell differentiation	Prdm1	IMP		Mouse	MGI:MGI:5779429\|PMID:27102484
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Prdm1	IMP	MGI:3605621,MGI:3052661	Mouse	PMID:28199486
Biological Process	GO:0009314	response to radiation	Prdm1	IEP		Rat	PMID:31286334\|RGD:150530479
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Prdm1	IMP	MGI:3605621,MGI:3052661	Mouse	PMID:28199486
Biological Process	GO:1990654	sebum secreting cell proliferation	Prdm1	IDA		Mouse	PMID:16901790
Biological Process	GO:0060707	trophoblast giant cell differentiation	Prdm1	IMP	MGI:MGI:5439582	Mouse	PMID:22987638
Biological Process	GO:0003281	ventricular septum development	Prdm1	IMP		Mouse	PMID:25807483

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.