Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRDM11
  • Mouse genes Prdm11
  • Rat genes Prdm11
  • Zfish genes prdm11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prdm11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Prdm11	IDA		Mouse	PMID:25499759
Molecular Function	GO:0005515	protein binding	PRDM11	IPI	UniProtKB:Q14192	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	PRDM11	IDA		Human	PMID:25499759
Cellular Component	GO:0005634	nucleus	PRDM11	IDA		Human	PMID:25499759
Biological Process	GO:0030308	negative regulation of cell growth	PRDM11	IDA		Human	PMID:25499759
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	PRDM11	IMP		Human	PMID:25499759
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	PRDM11	IMP		Human	PMID:25499759
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	PRDM11	IDA		Human	PMID:25499759
Biological Process	GO:0051726	regulation of cell cycle	PRDM11	IMP		Human	PMID:25499759
Biological Process	GO:0043408	regulation of MAPK cascade	PRDM11	IMP		Human	PMID:25499759

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern