Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRDM15
  • Mouse genes Prdm15
  • Rat genes Prdm15
  • Zfish genes prdm15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prdm15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990841	promoter-specific chromatin binding	Prdm15	IDA		Mouse	MGI:MGI:6120615|PMID:28740264
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Prdm15	IDA		Mouse	MGI:MGI:6120615|PMID:28740264
Cellular Component	GO:0016604	nuclear body	PRDM15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PRDM15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PRDM15	IDA		Human	PMID:15904895
Cellular Component	GO:0005634	nucleus	Prdm15	IDA		Mouse	MGI:MGI:6120615|PMID:28740264
Biological Process	GO:0043409	negative regulation of MAPK cascade	Prdm15	IMP		Mouse	MGI:MGI:6120615|PMID:28740264
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Prdm15	IMP		Mouse	MGI:MGI:6120615|PMID:28740264
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Prdm15	IDA		Mouse	MGI:MGI:6120615|PMID:28740264
Biological Process	GO:0060319	primitive erythrocyte differentiation	prdm15	IMP		Zfish	PMID:24240475
Biological Process	GO:2000035	regulation of stem cell division	Prdm15	IMP		Mouse	MGI:MGI:6120615|PMID:28740264

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern