Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRDM2
  • Mouse genes Prdm2
  • Rat genes Prdm2
  • Zfish genes prdm2a,prdm2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prdm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PRDM2	IDA		Human	PMID:8654390
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PRDM2	IMP		Human	PMID:8654390
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	PRDM2	IDA		Human	PMID:9334209
Molecular Function	GO:0005515	protein binding	Prdm2	IPI	RGD:731712	Rat	PMID:7538672|RGD:2316804
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	PRDM2	IMP		Human	PMID:8654390
Molecular Function	GO:0043565	sequence-specific DNA binding	PRDM2	IDA		Human	PMID:9334209
Cellular Component	GO:0005794	Golgi apparatus	PRDM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PRDM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PRDM2	IDA		Human	PMID:11544182
Cellular Component	GO:0005634	nucleus	Prdm2	IDA		Rat	PMID:7538672|RGD:2316804
Biological Process	GO:0008340	determination of adult lifespan	Prdm2	IMP	MGI:MGI:2388354	Mouse	PMID:11544182
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PRDM2	IDA		Human	PMID:9334209
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PRDM2	IDA		Human	PMID:8654390
Biological Process	GO:0032355	response to estradiol	Prdm2	IDA		Rat	PMID:10706618|RGD:2316803

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern