About   Help   FAQ
Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Prdx1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prdx1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0045296cadherin bindingPRDX1HDAHumanPMID:25468996
Molecular FunctionGO:0020037heme bindingPrdx1IPICHEBI:30413RatPMID:7577926|RGD:729570
Molecular FunctionGO:0042802identical protein bindingPrdx1IPIUniProtKB:P35700MouseMGI:MGI:5318005|PMID:21516123
Molecular FunctionGO:0042802identical protein bindingPrdx1IPIRGD:620039RatPMID:10535922|RGD:2291799
Molecular FunctionGO:0004601peroxidase activityPRDX1IDAHumanPMID:11986303
Molecular FunctionGO:0051920peroxiredoxin activityPrdx1IDARatPMID:11350800|RGD:2291832
Molecular FunctionGO:0051920peroxiredoxin activityPrdx1IDARatPMID:7488219|RGD:2291801
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:P58004HumanPMID:15105503
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:Q9Y6P5HumanPMID:15105503
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:P10275HumanPMID:17909037
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:Q9BYN0HumanPMID:18172504
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:P60484HumanPMID:19369943
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:P54274HumanPMID:21044950
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:Q78TU8HumanPMID:21969592
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:Q13043HumanPMID:23386615
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:P13693HumanPMID:27607350
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:P04156HumanPMID:28671123
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:Q86TI2-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingPRDX1IPIUniProtKB:Q8N7X4HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingPrdx1IPIUniProtKB:Q13043MouseMGI:MGI:5318005|PMID:21516123
Molecular FunctionGO:0003723RNA bindingPRDX1HDAHumanPMID:22658674
Molecular FunctionGO:0003723RNA bindingPRDX1HDAHumanPMID:22681889
Molecular FunctionGO:0008379thioredoxin peroxidase activityPRDX1IDAHumanPMID:18606987
Cellular ComponentGO:0005737cytoplasmPRDX1IDAHumanPMID:17603937
Cellular ComponentGO:0005737cytoplasmPrdx1IDARatPMID:14623930|RGD:2291802
Cellular ComponentGO:0005737cytoplasmPrdx1IDARatPMID:22023808|RGD:153297778
Cellular ComponentGO:0005737cytoplasmPrdx1IDARatPMID:29504286|RGD:152995491
Cellular ComponentGO:0005829cytosolPrdx1IDARatPMID:11350800|RGD:2291832
Cellular ComponentGO:0005829cytosolPrdx1IDARatPMID:7488219|RGD:2291801
Cellular ComponentGO:0005829cytosolPrdx1IDARatPMID:7577926|RGD:729570
Cellular ComponentGO:0000791euchromatinPrdx1IDARatPMID:14623930|RGD:2291802
Cellular ComponentGO:0070062extracellular exosomePRDX1HDAHumanPMID:19199708
Cellular ComponentGO:0070062extracellular exosomePRDX1HDAHumanPMID:20458337
Cellular ComponentGO:0070062extracellular exosomePRDX1HDAHumanPMID:23533145
Cellular ComponentGO:0005615extracellular spacePRDX1HDAHumanPMID:22664934
Cellular ComponentGO:0005615extracellular spacePRDX1HDAHumanPMID:23580065
Cellular ComponentGO:0005759mitochondrial matrixPrdx1IDARatPMID:14623930|RGD:2291802
Cellular ComponentGO:0005739mitochondrionPrdx1HDAMousePMID:18614015
Cellular ComponentGO:0043209myelin sheathPrdx1HDAMouseMGI:MGI:3834050|PMID:17634366
Cellular ComponentGO:0005730nucleolusPrdx1IDARatPMID:14623930|RGD:2291802
Cellular ComponentGO:0005634nucleusPRDX1IDAHumanPMID:17603937
Cellular ComponentGO:0005634nucleusPRDX1HDAHumanPMID:21630459
Cellular ComponentGO:0005782peroxisomal matrixPrdx1IDARatPMID:14623930|RGD:2291802
Cellular ComponentGO:0032991protein-containing complexprdx1IPIZFIN:ZDB-GENE-040219-8ZfishPMID:29518406
Biological ProcessGO:0034101erythrocyte homeostasisPrdx1IMPMGI:MGI:2670538MousePMID:12891360
Biological ProcessGO:0048144fibroblast proliferationPrdx1IMPMGI:MGI:2670538MousePMID:12891360
Biological ProcessGO:0042744hydrogen peroxide catabolic processPRDX1IDAHumanPMID:11986303
Biological ProcessGO:0042744hydrogen peroxide catabolic processPRDX1IDAHumanPMID:18606987
Biological ProcessGO:0045321leukocyte activationprdx1IMPZfishPMID:29518406
Biological ProcessGO:0030101natural killer cell activationPRDX1IDAHumanPMID:8462106
Biological ProcessGO:0042267natural killer cell mediated cytotoxicityPrdx1IMPMGI:MGI:2670538MousePMID:12891360
Biological ProcessGO:1901222regulation of NIK/NF-kappaB signalingPrdx1IMPMousePMID:15858817
Biological ProcessGO:0032872regulation of stress-activated MAPK cascadePrdx1IMPMousePMID:16880205
Biological ProcessGO:0019430removal of superoxide radicalsPrdx1IMPMousePMID:16880205
Biological ProcessGO:0019430removal of superoxide radicalsPrdx1IMPMGI:MGI:3611932MousePMID:16170382
Biological ProcessGO:0006979response to oxidative stressPrdx1IDAMousePMID:8360158
Biological ProcessGO:0006979response to oxidative stressPrdx1IMPMousePMID:15858817
Biological ProcessGO:0006979response to oxidative stressPrdx1IDARatPMID:17556052|RGD:2291828
Biological ProcessGO:0000302response to reactive oxygen speciesPrdx1IMPMGI:MGI:3611932MousePMID:16170382
Biological ProcessGO:0000302response to reactive oxygen speciesPrdx1IMPMGI:MGI:3611932MousePMID:16297875
Biological ProcessGO:0000302response to reactive oxygen speciesPrdx1IMPMGI:MGI:2670538MousePMID:12891360
Biological ProcessGO:0001895retina homeostasisPRDX1HEPHumanPMID:23580065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory