Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PREPL
  • Mouse genes Prepl
  • Rat genes Prepl
  • Zfish genes prepl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prepl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008233	peptidase activity	PREPL	IMP		Human	PMID:28726805
Molecular Function	GO:0008233	peptidase activity	Prepl	IMP		Mouse	MGI:MGI:6316505|PMID:21692504
Molecular Function	GO:0005515	protein binding	Prepl	IPI	UniProtKB:P35585	Mouse	MGI:MGI:6316362|PMID:23321636
Cellular Component	GO:0005856	cytoskeleton	Prepl	IDA		Mouse	PMID:23485813
Cellular Component	GO:0005794	Golgi apparatus	Prepl	IDA		Mouse	PMID:23485813
Cellular Component	GO:0005802	trans-Golgi network	Prepl	IMP		Mouse	MGI:MGI:6316362|PMID:23321636
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	Prepl	IMP		Mouse	MGI:MGI:6316362|PMID:23321636
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	PREPL	IMP		Human	PMID:24610330
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	Prepl	IMP		Mouse	MGI:MGI:6316362|PMID:23321636

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern