Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PREX1
  • Mouse genes Prex1
  • Rat genes Prex1
  • Zfish genes prex1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prex1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005543	phospholipid binding	PREX1	IDA		Human	PMID:11955434
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:P42345	Human	PMID:17565979
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:Q6R327	Human	PMID:17565979
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:Q8N122	Human	PMID:17565979
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:P31750	Human	PMID:21339740
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:Q6R327	Human	PMID:21339740
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:Q8N122	Human	PMID:21339740
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:P60953-2	Human	PMID:27150042
Molecular Function	GO:0005515	protein binding	PREX1	IPI	UniProtKB:P63000-1	Human	PMID:27150042
Cellular Component	GO:0005829	cytosol	PREX1	IDA		Human	PMID:11955434
Cellular Component	GO:0043198	dendritic shaft	Prex1	IDA		Rat	PMID:18697831|RGD:2314615
Cellular Component	GO:0030426	growth cone	Prex1	IDA		Rat	PMID:18697831|RGD:2314615
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Prex1	IDA		Rat	PMID:18697831|RGD:2314615
Cellular Component	GO:0005886	plasma membrane	Prex1	IDA		Rat	PMID:18697831|RGD:2314615
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Prex1	IGI	MGI:MGI:97845	Mouse	PMID:21178006
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Prex1	IGI	MGI:MGI:98923	Mouse	PMID:21178006
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Prex1	IGI	MGI:MGI:97846	Mouse	PMID:21178006
Biological Process	GO:0030593	neutrophil chemotaxis	Prex1	IGI	MGI:MGI:98923	Mouse	PMID:21179475
Biological Process	GO:0030593	neutrophil chemotaxis	Prex1	IGI	MGI:MGI:1888518	Mouse	PMID:21179475
Biological Process	GO:0038092	nodal signaling pathway	prex1	IMP	ZFIN:ZDB-MRPHLNO-121015-1	Zfish	PMID:22945937
Biological Process	GO:0045785	positive regulation of cell adhesion	Prex1	IGI	MGI:MGI:98923	Mouse	PMID:21178006
Biological Process	GO:0030335	positive regulation of cell migration	Prex1	IMP		Rat	PMID:15858067|RGD:11534004
Biological Process	GO:0043547	positive regulation of GTPase activity	Prex1	IGI	MGI:MGI:98923	Mouse	PMID:21178006
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	Prex1	IGI	MGI:MGI:98923	Mouse	PMID:21178006
Biological Process	GO:0072593	reactive oxygen species metabolic process	Prex1	IGI	MGI:MGI:98923	Mouse	PMID:21179475
Biological Process	GO:0030833	regulation of actin filament polymerization	Prex1	IMP		Rat	PMID:18697831|RGD:2314615
Biological Process	GO:0050773	regulation of dendrite development	Prex1	IMP		Rat	PMID:18697831|RGD:2314615
Biological Process	GO:0030217	T cell differentiation	Prex1	IGI	MGI:MGI:98923	Mouse	PMID:21178006

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern