Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Prickle1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PRICKLE1
- Mouse genes Prickle1
- Rat genes Prickle1
- Zfish genes prickle1a,prickle1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prickle1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q8VIG1	Human	PMID:14645515
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q8VIG1-2	Human	PMID:14645515
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q13127	Human	PMID:16417580
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q13127	Human	PMID:16442230
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q92997	Human	PMID:17030191
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q14203	Human	PMID:18922795
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q8VIG1	Human	PMID:18976727
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q08E77	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q8WWY3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q8WWY3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:O75564-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q13895	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRICKLE1	IPI	UniProtKB:Q9HAQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Prickle1	IPI	UniProtKB:Q8VIG1	Mouse	MGI:MGI:6854464\|PMID:34597683
Molecular Function	GO:0005515	protein binding	Prickle1	IPI	UniProtKB:Q80TV8	Mouse	PMID:27378169
Molecular Function	GO:0005515	protein binding	Prickle1	IPI	UniProtKB:Q8K1N2	Mouse	PMID:27378169
Molecular Function	GO:0005515	protein binding	Prickle1	IPI	UniProtKB:Q8BRT1	Mouse	PMID:27378169
Molecular Function	GO:0005515	protein binding	Prickle1	IPI	PR:P51141	Mouse	PMID:19788910
Molecular Function	GO:0005515	protein binding	Prickle1	IPI	UniProtKB:Q8VIG1	Rat	PMID:14645515\|RGD:1302877
Molecular Function	GO:0005515	protein binding	Prickle1	IPI	UniProtKB:Q8VIG1-2	Rat	PMID:14645515\|RGD:1302877
Molecular Function	GO:0005515	protein binding	prickle1a	IPI	ZFIN:ZDB-GENE-020507-3	Zfish	PMID:24021482
Molecular Function	GO:0044877	protein-containing complex binding	Prickle1	IDA		Mouse	PMID:27378169
Cellular Component	GO:0031254	cell trailing edge	Prickle1	IDA		Mouse	PMID:27378169
Cellular Component	GO:0005829	cytosol	PRICKLE1	IDA		Human	PMID:14645515
Cellular Component	GO:0005829	cytosol	PRICKLE1	IDA		Human	PMID:18922795
Cellular Component	GO:0016020	membrane	Prickle1	IMP		Mouse	PMID:27378169
Cellular Component	GO:0031965	nuclear membrane	PRICKLE1	IDA		Human	PMID:14645515
Cellular Component	GO:0031965	nuclear membrane	PRICKLE1	IDA		Human	PMID:16417580
Cellular Component	GO:0005634	nucleus	PRICKLE1	IDA		Human	PMID:14645515
Cellular Component	GO:0005634	nucleus	PRICKLE1	IDA		Human	PMID:16417580
Cellular Component	GO:0005634	nucleus	PRICKLE1	IDA		Human	PMID:18922795
Cellular Component	GO:0005634	nucleus	Prickle1	IDA		Mouse	PMID:22333836
Cellular Component	GO:0000502	proteasome complex	Prickle1	IDA		Mouse	PMID:25190059
Biological Process	GO:0009887	animal organ morphogenesis	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:1905070	anterior visceral endoderm cell migration	Prickle1	IMP	MGI:MGI:4356107	Mouse	PMID:19706528
Biological Process	GO:0035904	aorta development	Prickle1	IMP		Mouse	PMID:25807483
Biological Process	GO:0006915	apoptotic process	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0007409	axonogenesis	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0071711	basement membrane organization	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:0030282	bone mineralization	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0055013	cardiac muscle cell development	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0055013	cardiac muscle cell development	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0016477	cell migration	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0016477	cell migration	Prickle1	IGI	MGI:MGI:1923957	Mouse	PMID:27378169
Biological Process	GO:0016477	cell migration	Prickle1	IGI	MGI:MGI:2444981	Mouse	PMID:27378169
Biological Process	GO:0016477	cell migration	Prickle1	IMP		Mouse	PMID:27378169
Biological Process	GO:0021535	cell migration in hindbrain	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:17392791
Biological Process	GO:0042074	cell migration involved in gastrulation	prickle1a	IMP		Zfish	PMID:18976727
Biological Process	GO:0042074	cell migration involved in gastrulation	prickle1a	IMP		Zfish	PMID:12874125
Biological Process	GO:0042074	cell migration involved in gastrulation	prickle1a	IGI	ZFIN:ZDB-GENO-980202-263,ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:12874125
Biological Process	GO:0098609	cell-cell adhesion	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:0016043	cellular component organization	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0060271	cilium assembly	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0044782	cilium organization	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0060027	convergent extension involved in gastrulation	prickle1a	IGI	ZFIN:ZDB-MRPHLNO-060209-7,ZFIN:ZDB-MRPHLNO-080929-4	Zfish	PMID:18539122
Biological Process	GO:0060027	convergent extension involved in gastrulation	prickle1a	IGI	ZFIN:ZDB-MRPHLNO-120802-1,ZFIN:ZDB-MRPHLNO-120802-2	Zfish	PMID:22615492
Biological Process	GO:0060027	convergent extension involved in gastrulation	prickle1a	IGI	ZFIN:ZDB-MRPHLNO-060209-7,ZFIN:ZDB-MRPHLNO-080929-3	Zfish	PMID:18539122
Biological Process	GO:0061303	cornea development in camera-type eye	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:29450535
Biological Process	GO:0060976	coronary vasculature development	Prickle1	IMP		Mouse	PMID:25807483
Biological Process	GO:0007010	cytoskeleton organization	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0030705	cytoskeleton-dependent intracellular transport	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:0016358	dendrite development	Prickle1	IMP	MGI:MGI:5502459	Mouse	PMID:23420014
Biological Process	GO:0071907	determination of digestive tract left/right asymmetry	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-110413-4	Zfish	PMID:21215262
Biological Process	GO:0071910	determination of liver left/right asymmetry	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-110413-4	Zfish	PMID:21215262
Biological Process	GO:1990403	embryonic brain development	Prickle1	IMP		Mouse	PMID:17868671
Biological Process	GO:0042733	embryonic digit morphogenesis	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0030326	embryonic limb morphogenesis	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0035880	embryonic nail plate morphogenesis	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Prickle1	IMP		Mouse	PMID:27378169
Biological Process	GO:0061159	establishment of bipolar cell polarity involved in cell morphogenesis	Prickle1	IMP	MGI:MGI:4356107	Mouse	PMID:19706528
Biological Process	GO:0030010	establishment of cell polarity	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0030010	establishment of cell polarity	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0030010	establishment of cell polarity	Prickle1	IMP		Mouse	PMID:27378169
Biological Process	GO:0030010	establishment of cell polarity	Prickle1	IGI	MGI:MGI:2444981	Mouse	PMID:27378169
Biological Process	GO:0030010	establishment of cell polarity	Prickle1	IGI	MGI:MGI:1923957	Mouse	PMID:27378169
Biological Process	GO:0000132	establishment of mitotic spindle orientation	prickle1a	IGI	ZFIN:ZDB-MRPHLNO-060209-7,ZFIN:ZDB-MRPHLNO-140225-8	Zfish	PMID:24067530
Biological Process	GO:0045184	establishment of protein localization	Prickle1	IMP		Mouse	PMID:27378169
Biological Process	GO:0007163	establishment or maintenance of cell polarity	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0085029	extracellular matrix assembly	Prickle1	IMP	MGI:MGI:4356107	Mouse	PMID:19706528
Biological Process	GO:0061029	eyelid development in camera-type eye	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:29450535
Biological Process	GO:0060325	face morphogenesis	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0060325	face morphogenesis	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0021754	facial nucleus development	prickle1b	IMP	ZFIN:ZDB-GENO-110819-5	Zfish	PMID:25769695
Biological Process	GO:0021754	facial nucleus development	prickle1b	IMP	ZFIN:ZDB-MRPHLNO-071221-3,ZFIN:ZDB-MRPHLNO-071221-4	Zfish	PMID:17651720
Biological Process	GO:0120181	focal adhesion disassembly	Prickle1	IMP		Mouse	PMID:27378169
Biological Process	GO:0010467	gene expression	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0010467	gene expression	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0010467	gene expression	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0010467	gene expression	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:29450535
Biological Process	GO:0007507	heart development	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0001947	heart looping	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-081220-3	Zfish	PMID:20843857
Biological Process	GO:0001947	heart looping	prickle1a	IGI	ZFIN:ZDB-GENO-070316-4,ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:20843857
Biological Process	GO:0001947	heart looping	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:20843857
Biological Process	GO:0021934	hindbrain tangential cell migration	prickle1b	IMP	ZFIN:ZDB-MRPHLNO-071221-3,ZFIN:ZDB-MRPHLNO-071221-4	Zfish	PMID:17651720
Biological Process	GO:0035622	intrahepatic bile duct development	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-110413-4	Zfish	PMID:21215262
Biological Process	GO:0035622	intrahepatic bile duct development	prickle1a	IGI	ZFIN:ZDB-GENE-020104-1,ZFIN:ZDB-MRPHLNO-110413-4	Zfish	PMID:21215262
Biological Process	GO:0035622	intrahepatic bile duct development	prickle1a	IGI	ZFIN:ZDB-MRPHLNO-051214-2,ZFIN:ZDB-MRPHLNO-110413-4	Zfish	PMID:21215262
Biological Process	GO:0070121	Kupffer's vesicle development	prickle1a	IGI	ZFIN:ZDB-GENO-070316-4,ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:20843857
Biological Process	GO:0070121	Kupffer's vesicle development	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:20843857
Biological Process	GO:0070121	Kupffer's vesicle development	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-081220-3	Zfish	PMID:20843857
Biological Process	GO:0060173	limb development	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0035108	limb morphogenesis	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0060485	mesenchyme development	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:29450535
Biological Process	GO:0090307	mitotic spindle assembly	Prickle1	IMP	MGI:MGI:4356107	Mouse	PMID:19706528
Biological Process	GO:0097475	motor neuron migration	prickle1b	IMP	ZFIN:ZDB-MRPHLNO-071221-3,ZFIN:ZDB-MRPHLNO-071221-4	Zfish	PMID:20503357
Biological Process	GO:0097475	motor neuron migration	prickle1b	IMP	ZFIN:ZDB-GENO-110819-5	Zfish	PMID:25769695
Biological Process	GO:0035264	multicellular organism growth	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	PRICKLE1	IDA		Human	PMID:17030191
Biological Process	GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation	PRICKLE1	IDA		Human	PMID:21199191
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	PRICKLE1	IDA		Human	PMID:17030191
Biological Process	GO:0001755	neural crest cell migration	prickle1b	IMP	ZFIN:ZDB-MRPHLNO-071221-3	Zfish	PMID:30721665
Biological Process	GO:0001755	neural crest cell migration	prickle1b	IMP	ZFIN:ZDB-GENO-170328-2	Zfish	PMID:30721665
Biological Process	GO:0001755	neural crest cell migration	prickle1a	IMP	ZFIN:ZDB-GENO-200116-1	Zfish	PMID:30721665
Biological Process	GO:0003407	neural retina development	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:23324328
Biological Process	GO:0001843	neural tube closure	PRICKLE1	IMP		Human	PMID:21901791
Biological Process	GO:0001843	neural tube closure	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0001764	neuron migration	prickle1b	IGI	ZFIN:ZDB-MRPHLNO-071221-3,ZFIN:ZDB-MRPHLNO-100614-4	Zfish	PMID:21521740
Biological Process	GO:0001764	neuron migration	prickle1b	IMP	ZFIN:ZDB-GENO-110819-5	Zfish	PMID:21521740
Biological Process	GO:0001764	neuron migration	prickle1a	IGI	ZFIN:ZDB-GENO-980202-263	Zfish	PMID:12874125
Biological Process	GO:0031175	neuron projection development	Prickle1	IMP		Mouse	PMID:17868671
Biological Process	GO:0031175	neuron projection development	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-081220-3	Zfish	PMID:23324328
Biological Process	GO:0031175	neuron projection development	prickle1a	IMP	ZFIN:ZDB-MRPHLNO-060209-7	Zfish	PMID:23324328
Biological Process	GO:1990138	neuron projection extension	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:28837644
Biological Process	GO:0048812	neuron projection morphogenesis	Prickle1	IMP	MGI:MGI:5502459	Mouse	PMID:23420014
Biological Process	GO:0003151	outflow tract morphogenesis	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0003151	outflow tract morphogenesis	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:0061865	polarized secretion of basement membrane proteins in epithelium	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	PRICKLE1	IDA		Human	PMID:17030191
Biological Process	GO:0031398	positive regulation of protein ubiquitination	PRICKLE1	IDA		Human	PMID:17030191
Biological Process	GO:0036342	post-anal tail morphogenesis	Prickle1	IMP	MGI:MGI:4941929	Mouse	PMID:23913870
Biological Process	GO:0090009	primitive streak formation	Prickle1	IMP	MGI:MGI:4356107	Mouse	PMID:19706528
Biological Process	GO:0012501	programmed cell death	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:29450535
Biological Process	GO:0006606	protein import into nucleus	PRICKLE1	IMP		Human	PMID:14645515
Biological Process	GO:0006606	protein import into nucleus	PRICKLE1	IMP		Human	PMID:16417580
Biological Process	GO:0006606	protein import into nucleus	PRICKLE1	IDA		Human	PMID:21199191
Biological Process	GO:0006606	protein import into nucleus	Prickle1	IDA		Rat	PMID:14645515\|RGD:1302877
Biological Process	GO:0061326	renal tubule development	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0051602	response to electrical stimulus	Prickle1	IMP		Mouse	PMID:21276947
Biological Process	GO:0009410	response to xenobiotic stimulus	Prickle1	IMP		Mouse	PMID:21276947
Biological Process	GO:0070075	tear secretion	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:0009888	tissue development	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0001894	tissue homeostasis	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:29450535
Biological Process	GO:0016192	vesicle-mediated transport	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:33144400
Biological Process	GO:0016055	Wnt signaling pathway	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:25190059
Biological Process	GO:0016055	Wnt signaling pathway	Prickle1	IMP	MGI:MGI:5297388	Mouse	PMID:26883626
Biological Process	GO:0016055	Wnt signaling pathway	prickle1a	IGI	ZFIN:ZDB-GENO-980202-1037	Zfish	PMID:12874125
Biological Process	GO:0016055	Wnt signaling pathway	prickle1a	IGI	ZFIN:ZDB-GENO-980202-1367	Zfish	PMID:12874125
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	Prickle1	IMP	MGI:MGI:5645931	Mouse	PMID:29450535

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.