Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRICKLE2
  • Mouse genes Prickle2
  • Rat genes Prickle2
  • Zfish genes prickle2a,prickle2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prickle2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Prickle2	IPI	PR:P51141	Mouse	PMID:19788910
Cellular Component	GO:0016327	apicolateral plasma membrane	Prickle2	IDA		Mouse	PMID:17376975
Cellular Component	GO:0005737	cytoplasm	PRICKLE2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005737	cytoplasm	Prickle2	IDA		Mouse	PMID:22333836
Cellular Component	GO:0016328	lateral plasma membrane	Prickle2	IDA		Mouse	PMID:17376975
Biological Process	GO:0060271	cilium assembly	prickle2b	IMP	ZFIN:ZDB-MRPHLNO-180116-1	Zfish	PMID:24938409
Biological Process	GO:1990403	embryonic brain development	Prickle2	IMP		Mouse	PMID:17868671
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	Prickle2	IDA		Mouse	PMID:17376975
Biological Process	GO:0070121	Kupffer's vesicle development	prickle2b	IMP	ZFIN:ZDB-MRPHLNO-180116-1	Zfish	PMID:24938409
Biological Process	GO:0032402	melanosome transport	prickle2b	IGI	ZFIN:ZDB-MRPHLNO-060320-6,ZFIN:ZDB-MRPHLNO-180116-1	Zfish	PMID:24938409
Biological Process	GO:0003407	neural retina development	prickle2b	IMP	ZFIN:ZDB-MRPHLNO-180116-1	Zfish	PMID:24938409
Biological Process	GO:0031175	neuron projection development	Prickle2	IMP		Mouse	PMID:17868671
Biological Process	GO:0031175	neuron projection development	Prickle2	IMP		Mouse	PMID:19788910
Biological Process	GO:0051602	response to electrical stimulus	Prickle2	IMP	MGI:MGI:4941925	Mouse	PMID:21276947

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern