Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRIM2
  • Mouse genes Prim2
  • Rat genes Prim2
  • Zfish genes prim2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prim2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	PRIM2	IDA		Human	PMID:25550159
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	PRIM2	IDA		Human	PMID:26975377
Molecular Function	GO:0071667	DNA/RNA hybrid binding	PRIM2	IDA		Human	PMID:26975377
Molecular Function	GO:0005515	protein binding	PRIM2	IPI	UniProtKB:P49642	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRIM2	IPI	UniProtKB:P49642	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRIM2	IPI	UniProtKB:Q6P9E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRIM2	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Cellular Component	GO:0005658	alpha DNA polymerase:primase complex	PRIM2	IPI		Human	PMID:26975377
Cellular Component	GO:0005658	alpha DNA polymerase:primase complex	PRIM2	IDA		Human	PMID:26975377
Cellular Component	GO:0005658	alpha DNA polymerase:primase complex	PRIM2	IDA		Human	PMID:8026492
Cellular Component	GO:0005658	alpha DNA polymerase:primase complex	Prim2	IPI		Mouse	MGI:MGI:3687659|PMID:10523676
Cellular Component	GO:0005658	alpha DNA polymerase:primase complex	Prim2	IDA		Mouse	MGI:MGI:6478526|PMID:8026492
Biological Process	GO:0006270	DNA replication initiation	PRIM2	IDA		Human	PMID:26975377
Biological Process	GO:0006270	DNA replication initiation	Prim2	IDA		Mouse	MGI:MGI:3687659|PMID:10523676
Biological Process	GO:0006269	DNA replication, synthesis of RNA primer	PRIM2	IDA		Human	PMID:8026492
Biological Process	GO:0006269	DNA replication, synthesis of RNA primer	Prim2	IDA		Mouse	MGI:MGI:6478526|PMID:8026492
Biological Process	GO:1903934	positive regulation of DNA primase activity	PRIM2	IMP		Human	PMID:25550159

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern