Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKAG1
  • Mouse genes Prkag1
  • Rat genes Prkag1
  • Zfish genes prkag1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkag1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043531	ADP binding	Prkag1	IDA		Rat	PMID:21399626|RGD:7794795
Molecular Function	GO:0016208	AMP binding	Prkag1	IMP		Rat	PMID:10698692|RGD:1600480
Molecular Function	GO:0016208	AMP binding	Prkag1	IDA		Rat	PMID:16648175|RGD:1600447
Molecular Function	GO:0016208	AMP binding	Prkag1	IDA		Rat	PMID:17851531|RGD:8554140
Molecular Function	GO:0004679	AMP-activated protein kinase activity	Prkag1	IMP		Rat	PMID:10698692|RGD:1600480
Molecular Function	GO:0004679	AMP-activated protein kinase activity	Prkag1	IDA		Rat	PMID:14511394|RGD:1600691
Molecular Function	GO:0004679	AMP-activated protein kinase activity	Prkag1	IDA		Rat	PMID:16648175|RGD:1600447
Molecular Function	GO:0005524	ATP binding	Prkag1	IDA		Rat	PMID:17851531|RGD:8554140
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:16306228
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q8TF40	Human	PMID:17028174
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9P278	Human	PMID:18403135
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9Y478	Human	PMID:18480843
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O43741	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P54646	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9Y478	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O43741	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9Y478	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:22363791
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9Y478	Human	PMID:22363791
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O43741	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O43741	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P35520	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P54646	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q14145	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q6P1W5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q969V4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9BYR5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O43741	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P54646	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9Y478	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9Y484	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P54646	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P60370	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P60412	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q14145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q969V4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9BQ66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9BYQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q9Y478	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O43741	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P54646	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:Q13131	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:O75400-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRKAG1	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Prkag1	IPI	UniProtKB:Q9QXS1	Mouse	PMID:16608880
Molecular Function	GO:0005515	protein binding	Prkag1	IPI	RGD:71057	Rat	PMID:8626596|RGD:729494
Molecular Function	GO:0004672	protein kinase activity	PRKAG1	IDA		Human	PMID:17028174
Molecular Function	GO:0019901	protein kinase binding	PRKAG1	IDA		Human	PMID:10698692
Molecular Function	GO:0019901	protein kinase binding	Prkag1	IPI	RGD:3387	Rat	PMID:16648175|RGD:1600447
Molecular Function	GO:0019901	protein kinase binding	Prkag1	IPI	RGD:620893	Rat	PMID:16648175|RGD:1600447
Molecular Function	GO:0019887	protein kinase regulator activity	Prkag1	IDA		Rat	PMID:21399626|RGD:7794795
Molecular Function	GO:0044877	protein-containing complex binding	Prkag1	IDA		Rat	PMID:14511394|RGD:1600691
Cellular Component	GO:0016020	membrane	PRKAG1	HDA		Human	PMID:19946888
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	PRKAG1	IPI		Human	PMID:25412657
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	PRKAG1	IPI		Human	PMID:29480465
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	PRKAG1	IPI		Human	PMID:29657085
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	PRKAG1	IPI		Human	PMID:9693118
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	Prkag1	IDA		Rat	PMID:16648175|RGD:1600447
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	Prkag1	IDA		Rat	PMID:17851531|RGD:8554140
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	Prkag1	IDA		Rat	PMID:21399626|RGD:7794795
Cellular Component	GO:0005634	nucleus	PRKAG1	IDA		Human	PMID:9693118
Cellular Component	GO:0005634	nucleus	Prkag1	IDA		Mouse	PMID:10098881
Cellular Component	GO:0032991	protein-containing complex	Prkag1	IDA		Rat	PMID:14511394|RGD:1600691
Biological Process	GO:0031669	cellular response to nutrient levels	PRKAG1	IDA		Human	PMID:25412657
Biological Process	GO:0031669	cellular response to nutrient levels	PRKAG1	IDA		Human	PMID:30478170
Biological Process	GO:0051170	import into nucleus	Prkag1	IMP		Mouse	MGI:MGI:5810251|PMID:26021350
Biological Process	GO:0010628	positive regulation of gene expression	PRKAG1	IDA		Human	PMID:17028174
Biological Process	GO:0006468	protein phosphorylation	PRKAG1	IDA		Human	PMID:17028174
Biological Process	GO:0050790	regulation of catalytic activity	Prkag1	IDA		Rat	PMID:16648175|RGD:1600447

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern