Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKAR1B
  • Mouse genes Prkar1b
  • Rat genes Prkar1b
  • Zfish genes prkar1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkar1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030552	cAMP binding	Prkar1b	IDA		Rat	PMID:11907174|RGD:2312572
Molecular Function	GO:0004862	cAMP-dependent protein kinase inhibitor activity	PRKAR1B	IDA		Human	PMID:21812984
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	PRKAR1B	IDA		Human	PMID:21812984
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	Prkar1b	IDA		Rat	PMID:11907174|RGD:2312572
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	Prkar1b	IDA		Rat	PMID:16816331|RGD:2312556
Molecular Function	GO:0140678	molecular function inhibitor activity	PRKAR1B	EXP		Human	PMID:22797896
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P17612	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P17612	Human	PMID:24605759
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P10644	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P10644	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:A0A024R8L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:O43687-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:O60941-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:O94868-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:O95456	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:O95817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:O95983-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P10606	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P10644	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P10827	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P13631	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P13682	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P17612	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P33176	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P36508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P38936	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P43080	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P46379-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q05516	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q06455-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q13360-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q13573	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q14119	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q15561	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q15735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q16543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q2TAL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q3B820	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q49AR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q5T5Y3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q5VWN6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q86UD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q86UN6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q86VF2-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q86VK4-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q8IVT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q8IW40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q8IYS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q8NHY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q92529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q92569	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q92805	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q92917	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q969R5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q96BZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q96C24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q96E35	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q96G04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q96G25-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q96LK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q99633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9BZE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9BZF9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9H0W8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9H788	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9HC52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9NR33	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9NVN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9UBU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9UHR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:Q9UI36-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAR1B	IPI	UniProtKB:P17612	Human	PMID:32707033
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	PRKAR1B	IPI	UniProtKB:P17612-1	Human	PMID:21812984
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	PRKAR1B	IPI	UniProtKB:P17612-2	Human	PMID:21812984
Cellular Component	GO:0005952	cAMP-dependent protein kinase complex	Prkar1b	IDA		Mouse	PMID:21502359
Cellular Component	GO:0005952	cAMP-dependent protein kinase complex	Prkar1b	IDA		Rat	PMID:11907174|RGD:2312572
Cellular Component	GO:0005952	cAMP-dependent protein kinase complex	Prkar1b	IDA		Rat	PMID:16816331|RGD:2312556
Cellular Component	GO:0005737	cytoplasm	Prkar1b	IDA		Mouse	PMID:21502359
Cellular Component	GO:0005737	cytoplasm	Prkar1b	IDA		Rat	PMID:12210127|RGD:2312593
Cellular Component	GO:0098978	glutamatergic synapse	Prkar1b	IMP		Mouse	PMID:19447092
Cellular Component	GO:0098978	glutamatergic synapse	Prkar1b	IDA		Mouse	PMID:19447092
Cellular Component	GO:0098978	glutamatergic synapse	Prkar1b	IMP		Mouse	PMID:7568030
Cellular Component	GO:0098978	glutamatergic synapse	Prkar1b	IDA		Mouse	PMID:7568030
Cellular Component	GO:0098978	glutamatergic synapse	Prkar1b	IDA		Mouse	PMID:24413018
Cellular Component	GO:0098978	glutamatergic synapse	Prkar1b	EXP		Mouse	PMID:24413018
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Prkar1b	IMP		Mouse	PMID:8548807
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Prkar1b	IDA		Mouse	PMID:8548807
Cellular Component	GO:0005771	multivesicular body	Prkar1b	IDA		Mouse	PMID:21502359
Cellular Component	GO:0098794	postsynapse	Prkar1b	IDA		Mouse	PMID:19447092
Cellular Component	GO:0098794	postsynapse	Prkar1b	IMP		Mouse	PMID:19447092
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Prkar1b	IMP		Mouse	PMID:9054501
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Prkar1b	IDA		Mouse	PMID:9054501
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Prkar1b	IMP		Mouse	PMID:7568030
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Prkar1b	IDA		Mouse	PMID:7568030
Cellular Component	GO:0045202	synapse	Prkar1b	EXP		Mouse	PMID:24413018
Cellular Component	GO:0045202	synapse	Prkar1b	IDA		Mouse	PMID:24413018
Biological Process	GO:0007611	learning or memory	Prkar1b	IMP	MGI:MGI:2158640	Mouse	PMID:7568030
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Prkar1b	IMP		Mouse	PMID:9054501
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Prkar1b	IDA		Mouse	PMID:9054501
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Prkar1b	IDA		Mouse	PMID:7568030
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Prkar1b	IMP		Mouse	PMID:7568030
Biological Process	GO:2000480	negative regulation of cAMP-dependent protein kinase activity	PRKAR1B	IDA		Human	PMID:21812984
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Prkar1b	IMP		Rat	PMID:33479380|RGD:150519900
Biological Process	GO:1903367	positive regulation of fear response	Prkar1b	IMP		Rat	PMID:33479380|RGD:150519900
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Prkar1b	IMP		Rat	PMID:33479380|RGD:150519900
Biological Process	GO:1904058	positive regulation of sensory perception of pain	Prkar1b	IMP		Rat	PMID:33479380|RGD:150519900
Biological Process	GO:0045859	regulation of protein kinase activity	Prkar1b	IDA		Rat	PMID:11907174|RGD:2312572
Biological Process	GO:0045859	regulation of protein kinase activity	Prkar1b	IDA		Rat	PMID:16816331|RGD:2312556
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Prkar1b	IMP		Mouse	PMID:8548807
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Prkar1b	IDA		Mouse	PMID:8548807

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern