Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKCG
  • Mouse genes Prkcg
  • Rat genes Prkcg
  • Zfish genes prkcg
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkcg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004698	calcium-dependent protein kinase C activity	Prkcg	IDA		Rat	PMID:18972403|RGD:5131882
Molecular Function	GO:0005515	protein binding	PRKCG	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	PRKCG	IPI	UniProtKB:P08238	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PRKCG	IPI	UniProtKB:O75925	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRKCG	IPI	UniProtKB:P08727	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRKCG	IPI	UniProtKB:Q8N6K7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRKCG	IPI	UniProtKB:Q8TDR4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRKCG	IPI	UniProtKB:Q96KS9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Prkcg	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:5467682|PMID:23185022
Molecular Function	GO:0005515	protein binding	Prkcg	IPI	UniProtKB:P19493	Rat	PMID:12471040|RGD:8554457
Molecular Function	GO:0005515	protein binding	Prkcg	IPI	UniProtKB:P53667	Rat	PMID:8940095|RGD:632670
Molecular Function	GO:0005515	protein binding	Prkcg	IPI	RGD:708404	Rat	PMID:9514928|RGD:1299423
Molecular Function	GO:0004672	protein kinase activity	PRKCG	IDA		Human	PMID:15808853
Molecular Function	GO:0004697	protein kinase C activity	Prkcg	IDA		Rat	PMID:11507002|RGD:631236
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	PRKCG	IDA		Human	PMID:22797923
Cellular Component	GO:0044305	calyx of Held	Prkcg	IDA		Mouse	PMID:24794094
Cellular Component	GO:0044305	calyx of Held	Prkcg	IMP		Mouse	PMID:24794094
Cellular Component	GO:0005911	cell-cell junction	Prkcg	IDA		Mouse	PMID:23793062
Cellular Component	GO:0005737	cytoplasm	Prkcg	IDA		Mouse	MGI:MGI:3763599|PMID:17904530
Cellular Component	GO:0005737	cytoplasm	Prkcg	IDA		Mouse	PMID:14613966
Cellular Component	GO:0005737	cytoplasm	Prkcg	IDA		Mouse	PMID:10882525
Cellular Component	GO:0005737	cytoplasm	Prkcg	IDA		Mouse	PMID:11549583
Cellular Component	GO:0005829	cytosol	Prkcg	IDA		Rat	PMID:10501452|RGD:28867228
Cellular Component	GO:0005829	cytosol	Prkcg	IDA		Rat	PMID:12471040|RGD:8554457
Cellular Component	GO:0005829	cytosol	Prkcg	IDA		Rat	PMID:12560106|RGD:28867224
Cellular Component	GO:0005829	cytosol	Prkcg	IDA		Rat	PMID:14688616|RGD:1358416
Cellular Component	GO:0005829	cytosol	Prkcg	IDA		Rat	PMID:18972403|RGD:5131882
Cellular Component	GO:0005829	cytosol	Prkcg	IDA		Rat	PMID:9705215|RGD:5131655
Cellular Component	GO:0030425	dendrite	Prkcg	IDA		Mouse	PMID:11549583
Cellular Component	GO:0030425	dendrite	Prkcg	IDA		Rat	PMID:12471040|RGD:8554457
Cellular Component	GO:0016020	membrane	Prkcg	IDA		Rat	PMID:10501452|RGD:28867228
Cellular Component	GO:0043005	neuron projection	Prkcg	IDA		Rat	PMID:14688616|RGD:1358416
Cellular Component	GO:0005634	nucleus	Prkcg	IDA		Mouse	PMID:14613966
Cellular Component	GO:0005634	nucleus	Prkcg	IDA		Mouse	PMID:10882525
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Prkcg	IDA		Rat	PMID:12471040|RGD:8554457
Cellular Component	GO:0005886	plasma membrane	Prkcg	IDA		Mouse	MGI:MGI:3763599|PMID:17904530
Cellular Component	GO:0005886	plasma membrane	Prkcg	IDA		Mouse	PMID:10882525
Cellular Component	GO:0005886	plasma membrane	Prkcg	IDA		Rat	PMID:12471040|RGD:8554457
Cellular Component	GO:0005886	plasma membrane	Prkcg	IDA		Rat	PMID:18972403|RGD:5131882
Cellular Component	GO:0099524	postsynaptic cytosol	Prkcg	IDA		Rat	PMID:2202488|RGD:13702285
Cellular Component	GO:0014069	postsynaptic density	Prkcg	IDA		Mouse	PMID:17114649
Cellular Component	GO:0099523	presynaptic cytosol	Prkcg	IDA		Mouse	PMID:24794094
Cellular Component	GO:0097060	synaptic membrane	Prkcg	IDA		Mouse	MGI:MGI:5285815|PMID:18473171
Cellular Component	GO:0097060	synaptic membrane	Prkcg	IDA		Rat	PMID:12560106|RGD:28867224
Biological Process	GO:0007268	chemical synaptic transmission	Prkcg	IMP		Mouse	MGI:MGI:78713|PMID:8548809
Biological Process	GO:0007635	chemosensory behavior	Prkcg	IMP	MGI:MGI:1857237	Mouse	PMID:11606660
Biological Process	GO:0060384	innervation	Prkcg	IMP		Mouse	MGI:MGI:78713|PMID:8548809
Biological Process	GO:0007611	learning or memory	Prkcg	IEP		Rat	PMID:12000125|RGD:633712
Biological Process	GO:0060291	long-term synaptic potentiation	Prkcg	IDA		Rat	PMID:10501452|RGD:28867228
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Prkcg	IMP		Rat	PMID:15705736|RGD:8553897
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	Prkcg	IMP		Mouse	MGI:MGI:5467682|PMID:23185022
Biological Process	GO:0042177	negative regulation of protein catabolic process	PRKCG	IDA		Human	PMID:15808853
Biological Process	GO:0031397	negative regulation of protein ubiquitination	PRKCG	IDA		Human	PMID:15808853
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Prkcg	IMP		Mouse	MGI:MGI:5467682|PMID:23185022
Biological Process	GO:0016310	phosphorylation	PRKCG	IDA		Human	PMID:15808853
Biological Process	GO:0032425	positive regulation of mismatch repair	PRKCG	IDA		Human	PMID:15808853
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Prkcg	IDA		Mouse	PMID:24794094
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Prkcg	IMP		Mouse	PMID:24794094
Biological Process	GO:0046777	protein autophosphorylation	Prkcg	IDA		Rat	PMID:18972403|RGD:5131882
Biological Process	GO:0001881	receptor recycling	prkcg	IDA		Zfish	PMID:19366675
Biological Process	GO:0001881	receptor recycling	prkcg	IDA		Zfish	PMID:20525069
Biological Process	GO:0042752	regulation of circadian rhythm	Prkcg	IMP		Mouse	MGI:MGI:5467682|PMID:23185022
Biological Process	GO:0050764	regulation of phagocytosis	Prkcg	IMP		Mouse	PMID:15006698
Biological Process	GO:0032095	regulation of response to food	Prkcg	IMP		Mouse	MGI:MGI:5467682|PMID:23185022
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Prkcg	IDA		Mouse	PMID:24794094
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Prkcg	IMP		Mouse	PMID:24794094
Biological Process	GO:0043278	response to morphine	Prkcg	IMP		Mouse	MGI:MGI:3760696|PMID:11246146
Biological Process	GO:0048265	response to pain	Prkcg	IMP		Mouse	MGI:MGI:1097759|PMID:9323205
Biological Process	GO:1990911	response to psychosocial stress	Prkcg	IDA		Rat	PMID:9287082|RGD:8554746
Biological Process	GO:0009636	response to toxic substance	Prkcg	IEP		Rat	PMID:12560106|RGD:28867224
Biological Process	GO:0060074	synapse maturation	prkcg	IMP	ZFIN:ZDB-MRPHLNO-100623-3	Zfish	PMID:20525069

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern