Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Prkcq

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PRKCQ
- Mouse genes Prkcq
- Rat genes Prkcq
- Zfish genes prkcq
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkcq

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:P06241	Human	PMID:10383400
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:O76003	Human	PMID:10636891
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:Q06187	Human	PMID:11788586
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:Q9H8V3	Human	PMID:15254234
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:Q05513	Human	PMID:17588663
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:P06239	Human	PMID:21964608
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:Q8IVH8	Human	PMID:21983831
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:P35570	Human	PMID:23352416
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:Q00613	Human	PMID:23352416
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:Q3V6T2	Human	PMID:23509302
Molecular Function	GO:0005515	protein binding	PRKCQ	IPI	UniProtKB:C0HM02	Human	PMID:34593629
Molecular Function	GO:0005515	protein binding	Prkcq	IPI	UniProtKB:Q8IVH8\|UniProtKB:Q99JP0	Mouse	MGI:MGI:5295782\|PMID:21983831
Molecular Function	GO:0005515	protein binding	Prkcq	IPI	UniProtKB:P26645\|UniProtKB:Q61072\|UniProtKB:Q91VJ2	Mouse	MGI:MGI:1326990\|PMID:9857183
Molecular Function	GO:0005515	protein binding	Prkcq	IPI	UniProtKB:P70257-2	Mouse	MGI:MGI:4454367\|PMID:20178747
Molecular Function	GO:0005515	protein binding	Prkcq	IPI	RGD:2230	Rat	PMID:11698413\|RGD:1625615
Molecular Function	GO:0004672	protein kinase activity	PRKCQ	IDA		Human	PMID:34593629
Molecular Function	GO:0004697	protein kinase C activity	PRKCQ	EXP		Human	PMID:16356856
Molecular Function	GO:0004697	protein kinase C activity	Prkcq	IDA		Mouse	PMID:12618484
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Prkcq	IDA		Rat	PMID:12697665\|RGD:724661
Cellular Component	GO:0016235	aggresome	PRKCQ	IDA		Human	GO_REF:0000052
Cellular Component	GO:0034451	centriolar satellite	PRKCQ	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Prkcq	IDA		Mouse	PMID:12618484
Cellular Component	GO:0005737	cytoplasm	Prkcq	IDA		Mouse	PMID:12867038
Cellular Component	GO:0005737	cytoplasm	Prkcq	IDA		Rat	PMID:11698413\|RGD:1625615
Cellular Component	GO:0001772	immunological synapse	Prkcq	IDA		Mouse	PMID:11728336
Cellular Component	GO:0001772	immunological synapse	Prkcq	IDA		Mouse	PMID:15117976
Cellular Component	GO:0001772	immunological synapse	Prkcq	IDA		Mouse	PMID:12867038
Cellular Component	GO:0001772	immunological synapse	Prkcq	IDA		Mouse	PMID:23793062
Cellular Component	GO:0001772	immunological synapse	Prkcq	IDA		Mouse	PMID:15128768
Cellular Component	GO:0001772	immunological synapse	prkcq	IDA		Zfish	PMID:30408601
Cellular Component	GO:0016020	membrane	Prkcq	IDA		Rat	PMID:11404218\|RGD:1625602
Cellular Component	GO:0031594	neuromuscular junction	Prkcq	IDA		Rat	PMID:7738116\|RGD:1625624
Cellular Component	GO:0005634	nucleus	Prkcq	IDA		Rat	PMID:10944456\|RGD:1625618
Cellular Component	GO:0005886	plasma membrane	Prkcq	IDA		Mouse	PMID:12867038
Cellular Component	GO:0005886	plasma membrane	Prkcq	IDA		Mouse	PMID:12618484
Cellular Component	GO:0042383	sarcolemma	Prkcq	IDA		Rat	PMID:7738116\|RGD:1625624
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	Prkcq	IMP	MGI:MGI:2664379	Mouse	PMID:12867038
Biological Process	GO:0060326	cell chemotaxis	PRKCQ	IMP		Human	PMID:24008408
Biological Process	GO:0032623	interleukin-2 production	Prkcq	IMP	MGI:MGI:2664379	Mouse	PMID:12867038
Biological Process	GO:0035556	intracellular signal transduction	Prkcq	IMP	MGI:MGI:2664379	Mouse	PMID:12867038
Biological Process	GO:0035556	intracellular signal transduction	Prkcq	IDA		Rat	PMID:12697665\|RGD:724661
Biological Process	GO:0006509	membrane protein ectodomain proteolysis	Prkcq	IDA		Mouse	MGI:MGI:1326990\|PMID:9857183
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	PRKCQ	IMP		Human	PMID:15364919
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	PRKCQ	IMP		Human	PMID:11342610
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	PRKCQ	IMP		Human	PMID:16709830
Biological Process	GO:0030182	neuron differentiation	Prkcq	IEP		Rat	PMID:10944456\|RGD:1625618
Biological Process	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation	Prkcq	IMP	MGI:MGI:2664379	Mouse	PMID:12867038
Biological Process	GO:0051491	positive regulation of filopodium assembly	Prkcq	IMP		Rat	PMID:9353339\|RGD:1625621
Biological Process	GO:0032740	positive regulation of interleukin-17 production	Prkcq	IMP		Mouse	MGI:MGI:3769226\|PMID:16493044
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Prkcq	IMP	MGI:MGI:2664379	Mouse	PMID:12867038
Biological Process	GO:0032753	positive regulation of interleukin-4 production	Prkcq	IMP		Mouse	MGI:MGI:3587418\|PMID:15263025
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	PRKCQ	IDA		Human	PMID:16356855
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Prkcq	IMP		Mouse	MGI:MGI:2663371\|PMID:12782715
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Prkcq	IMP		Rat	PMID:12697665\|RGD:724661
Biological Process	GO:0050714	positive regulation of protein secretion	Prkcq	IDA		Rat	PMID:11095914\|RGD:1625617
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Prkcq	IMP		Rat	PMID:9353339\|RGD:1625621
Biological Process	GO:0050870	positive regulation of T cell activation	Prkcq	IMP		Mouse	MGI:MGI:2663371\|PMID:12782715
Biological Process	GO:0050870	positive regulation of T cell activation	Prkcq	IMP	MGI:MGI:2664379	Mouse	PMID:12867038
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	Prkcq	IMP		Mouse	MGI:MGI:3769226\|PMID:16493044
Biological Process	GO:2000570	positive regulation of T-helper 2 cell activation	Prkcq	IMP		Mouse	MGI:MGI:3587418\|PMID:15263025
Biological Process	GO:0051973	positive regulation of telomerase activity	PRKCQ	IMP		Human	PMID:21531765
Biological Process	GO:1904355	positive regulation of telomere capping	PRKCQ	IMP		Human	PMID:21531765
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	PRKCQ	IMP		Human	PMID:21531765
Biological Process	GO:0006468	protein phosphorylation	PRKCQ	IDA		Human	PMID:34593629
Biological Process	GO:0006468	protein phosphorylation	Prkcq	IDA		Mouse	PMID:12618484
Biological Process	GO:0006355	regulation of DNA-templated transcription	Prkcq	IMP		Mouse	MGI:MGI:2663371\|PMID:12782715
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	Prkcq	IMP		Rat	PMID:9353339\|RGD:1625621
Biological Process	GO:0090330	regulation of platelet aggregation	Prkcq	IMP		Mouse	MGI:MGI:3851048\|PMID:19433059
Biological Process	GO:0019229	regulation of vasoconstriction	Prkcq	IEP		Rat	PMID:16951045\|RGD:1625607
Biological Process	GO:0045730	respiratory burst	Prkcq	IEP		Rat	PMID:10218646\|RGD:1625619
Biological Process	GO:0009749	response to glucose	Prkcq	IEP		Rat	PMID:11914741\|RGD:1625601
Biological Process	GO:0009408	response to heat	Prkcq	IEP		Rat	PMID:11735277\|RGD:1625613
Biological Process	GO:0001666	response to hypoxia	Prkcq	IEP		Rat	PMID:15994856\|RGD:1625608
Biological Process	GO:0032868	response to insulin	Prkcq	IEP		Rat	PMID:7755564\|RGD:1625623
Biological Process	GO:0014070	response to organic cyclic compound	Prkcq	IEP		Rat	PMID:11404218\|RGD:1625602
Biological Process	GO:0042110	T cell activation	Prkcq	IMP	MGI:MGI:2664379	Mouse	PMID:12867038
Biological Process	GO:0042246	tissue regeneration	Prkcq	IEP		Rat	PMID:12007632\|RGD:1625612

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.