Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKCSH
  • Mouse genes Prkcsh
  • Rat genes Prkcsh
  • Zfish genes prkcsh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkcsh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Prkcsh	IDA		Mouse	MGI:MGI:6158858|PMID:27462106
Molecular Function	GO:0051219	phosphoprotein binding	PRKCSH	IPI	UniProtKB:Q13563	Human	PMID:19801576
Molecular Function	GO:0005515	protein binding	PRKCSH	IPI	UniProtKB:Q14697	Human	PMID:10929008
Molecular Function	GO:0005515	protein binding	PRKCSH	IPI	UniProtKB:Q14697-1	Human	PMID:10929008
Molecular Function	GO:0005515	protein binding	PRKCSH	IPI	UniProtKB:Q14697-2	Human	PMID:10929008
Molecular Function	GO:0005515	protein binding	Prkcsh	IPI	UniProtKB:Q8BHN3	Mouse	MGI:MGI:6158858|PMID:27462106
Molecular Function	GO:0005515	protein binding	Prkcsh	IPI	PR:Q505D9	Mouse	PMID:22337885
Molecular Function	GO:0005515	protein binding	Prkcsh	IPI	PR:P06800	Mouse	PMID:9148925
Molecular Function	GO:0005515	protein binding	Prkcsh	IPI	PR:Q7TME0	Mouse	PMID:22337885
Molecular Function	GO:0005080	protein kinase C binding	PRKCSH	IPI	UniProtKB:Q05513	Human	PMID:15707389
Molecular Function	GO:0044877	protein-containing complex binding	Prkcsh	IPI	RGD:3399|RGD:619968	Rat	PMID:15707389|RGD:1642697
Molecular Function	GO:0003723	RNA binding	Prkcsh	IDA		Mouse	PMID:16706842
Molecular Function	GO:0044325	transmembrane transporter binding	PRKCSH	IPI	UniProtKB:Q8NER1	Human	PMID:19801576
Cellular Component	GO:0005783	endoplasmic reticulum	PRKCSH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	PRKCSH	IDA		Human	PMID:19801576
Cellular Component	GO:0017177	glucosidase II complex	PRKCSH	IPI		Human	PMID:10929008
Cellular Component	GO:0017177	glucosidase II complex	PRKCSH	IDA		Human	PMID:10929008
Cellular Component	GO:0017177	glucosidase II complex	Prkcsh	IDA		Mouse	MGI:MGI:6158858|PMID:27462106
Cellular Component	GO:0017177	glucosidase II complex	Prkcsh	IPI	UniProtKB:O08794	Mouse	PMID:9148925
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PRKCSH	IMP		Human	PMID:10929008
Biological Process	GO:0001701	in utero embryonic development	Prkcsh	IMP	MGI:MGI:5442302	Mouse	PMID:21685914
Biological Process	GO:0001889	liver development	Prkcsh	IGI	MGI:MGI:2155302	Mouse	PMID:21685914
Biological Process	GO:0001889	liver development	prkcsh	IMP	ZFIN:ZDB-MRPHLNO-100224-1	Zfish	PMID:23668934
Biological Process	GO:0006491	N-glycan processing	PRKCSH	IDA		Human	PMID:10929008
Biological Process	GO:0010977	negative regulation of neuron projection development	Prkcsh	IMP		Mouse	PMID:22337885
Biological Process	GO:0006807	nitrogen compound metabolic process	Prkcsh	IGI	MGI:MGI:97603	Mouse	PMID:21685914
Biological Process	GO:0048793	pronephros development	prkcsh	IGI	ZFIN:ZDB-MRPHLNO-070129-2,ZFIN:ZDB-MRPHLNO-100224-1	Zfish	PMID:19801576
Biological Process	GO:0048793	pronephros development	prkcsh	IGI	ZFIN:ZDB-GENE-040827-4	Zfish	PMID:19801576

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern