Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKRA
  • Mouse genes Prkra
  • Rat genes Prkra
  • Zfish genes prkra
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkra

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	PRKRA	IDA		Human	PMID:23661684
Molecular Function	GO:0019899	enzyme binding	PRKRA	IPI	UniProtKB:Q9UPY3	Human	PMID:23661684
Molecular Function	GO:0042802	identical protein binding	PRKRA	IPI	UniProtKB:O75569	Human	PMID:16169070
Molecular Function	GO:0042802	identical protein binding	PRKRA	IPI	UniProtKB:O75569	Human	PMID:21900206
Molecular Function	GO:0042802	identical protein binding	PRKRA	IPI	UniProtKB:O75569	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	PRKRA	IPI	UniProtKB:O75569	Human	PMID:32296183
Molecular Function	GO:0070883	pre-miRNA binding	PRKRA	IDA		Human	PMID:23661684
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q15633	Human	PMID:16424907
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9UKV8	Human	PMID:16424907
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9UPY3	Human	PMID:16424907
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q15633	Human	PMID:17452327
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9UPY3	Human	PMID:17452327
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9NX74	Human	PMID:18096616
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P03496	Human	PMID:20064372
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9NX58	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9UPY3	Human	PMID:21858095
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:O15226	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q15633	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P19525	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q67020	Human	PMID:21994455
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P03496	Human	PMID:22810585
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P19525	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9UKV8	Human	PMID:23661684
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9UPY3	Human	PMID:23661684
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P03496	Human	PMID:23853584
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:O95786	Human	PMID:23870315
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q05127	Human	PMID:23870315
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q15633	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9HA38	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9NX58	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q15633	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:O95786	Human	PMID:28591694
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P03416	Human	PMID:28591694
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P59595	Human	PMID:28591694
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9BYX4	Human	PMID:28591694
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9NX58	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:O15226	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:O95793	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P19525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P78563-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q15633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q96SI9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:Q9H898-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P19525	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PRKRA	IPI	UniProtKB:P0DTC9	Human	PMID:35075101
Molecular Function	GO:0005515	protein binding	Prkra	IPI	UniProtKB:P97473	Mouse	MGI:MGI:3843425|PMID:17452327
Molecular Function	GO:0042803	protein homodimerization activity	PRKRA	IPI	UniProtKB:O75569	Human	PMID:17452327
Molecular Function	GO:0019901	protein kinase binding	Prkra	IPI	RGD:3402	Rat	PMID:17953670|RGD:2301732
Molecular Function	GO:0003723	RNA binding	PRKRA	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	PRKRA	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005737	cytoplasm	PRKRA	IDA		Human	PMID:17452327
Cellular Component	GO:0005737	cytoplasm	Prkra	IDA		Rat	PMID:21897745|RGD:7777145
Cellular Component	GO:0005829	cytosol	PRKRA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005622	intracellular anatomical structure	Prkra	IDA		Mouse	PMID:16571658
Cellular Component	GO:0016020	membrane	PRKRA	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	PRKRA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070578	RISC-loading complex	PRKRA	IPI		Human	PMID:23661684
Cellular Component	GO:0070578	RISC-loading complex	PRKRA	IDA		Human	PMID:23661684
Biological Process	GO:0034599	cellular response to oxidative stress	Prkra	IDA		Mouse	PMID:10336432
Biological Process	GO:0043583	ear development	Prkra	IMP	MGI:MGI:5692073	Mouse	PMID:26234751
Biological Process	GO:0043583	ear development	Prkra	IMP	MGI:MGI:4442398	Mouse	PMID:26234751
Biological Process	GO:0043583	ear development	Prkra	IMP	MGI:MGI:4442387	Mouse	PMID:26234751
Biological Process	GO:0043583	ear development	Prkra	IMP	MGI:MGI:5461152	Mouse	PMID:26234751
Biological Process	GO:0042474	middle ear morphogenesis	Prkra	IMP	MGI:MGI:3626341	Mouse	PMID:16571658
Biological Process	GO:0035196	miRNA processing	PRKRA	IDA		Human	PMID:23661684
Biological Process	GO:0042473	outer ear morphogenesis	Prkra	IMP	MGI:MGI:3626341	Mouse	PMID:16571658
Biological Process	GO:0008284	positive regulation of cell population proliferation	Prkra	IMP		Rat	PMID:19541653|RGD:7777147
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	Prkra	IDA		Mouse	PMID:12181197
Biological Process	GO:0031054	pre-miRNA processing	PRKRA	IDA		Human	PMID:16424907
Biological Process	GO:0031054	pre-miRNA processing	PRKRA	IDA		Human	PMID:23661684
Biological Process	GO:0006468	protein phosphorylation	Prkra	IDA		Mouse	PMID:10336432
Biological Process	GO:0050821	protein stabilization	PRKRA	IMP		Human	PMID:16424907
Biological Process	GO:0030422	siRNA processing	PRKRA	IDA		Human	PMID:17452327
Biological Process	GO:0048705	skeletal system morphogenesis	Prkra	IMP	MGI:MGI:3626341	Mouse	PMID:16571658

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern