Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRMT6
  • Mouse genes Prmt6
  • Rat genes Prmt6
  • Zfish genes prmt6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prmt6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Prmt6	IDA		Mouse	PMID:22904064
Molecular Function	GO:0008469	histone arginine N-methyltransferase activity	PRMT6	EXP		Human	PMID:19509293
Molecular Function	GO:0008469	histone arginine N-methyltransferase activity	PRMT6	EXP		Human	PMID:22777353
Molecular Function	GO:0008469	histone arginine N-methyltransferase activity	PRMT6	IDA		Human	PMID:23980157
Molecular Function	GO:0042393	histone binding	PRMT6	IDA		Human	PMID:17898714
Molecular Function	GO:0042393	histone binding	PRMT6	IDA		Human	PMID:18079182
Molecular Function	GO:0070612	histone H2AR3 methyltransferase activity	PRMT6	IDA		Human	PMID:18079182
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	prmt6	IMP	ZFIN:ZDB-MRPHLNO-141215-14	Zfish	PMID:26487724
Molecular Function	GO:0070611	histone H3R2 methyltransferase activity	PRMT6	IDA		Human	PMID:17898714
Molecular Function	GO:0070611	histone H3R2 methyltransferase activity	PRMT6	IDA		Human	PMID:18079182
Molecular Function	GO:0070611	histone H3R2 methyltransferase activity	Prmt6	IMP		Mouse	PMID:22904064
Molecular Function	GO:0070611	histone H3R2 methyltransferase activity	prmt6	IMP	ZFIN:ZDB-MRPHLNO-141215-14	Zfish	PMID:26487724
Molecular Function	GO:0044020	histone H4R3 methyltransferase activity	PRMT6	IDA		Human	PMID:18079182
Molecular Function	GO:0042054	histone methyltransferase activity	PRMT6	IDA		Human	PMID:19405910
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:P17096	Human	PMID:16157300
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:P17096-1	Human	PMID:16293633
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:P52926	Human	PMID:16293633
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:P06746	Human	PMID:16600869
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:O00231	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:O14645	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:O15198	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:P00973	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:P50749	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q14995	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q6P047	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q86SE9	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q8N1K5	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q8NEC7	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q8TE85	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q96BD6	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q96EY1	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q96H20	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q96JB6	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9BQS8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9BX10	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9BXL8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9H204	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9HAQ2	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9UBX0	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9UGK8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9Y2M5	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9Y365	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9Y3A6	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:A8K932	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRMT6	IPI	UniProtKB:Q9NRC8	Human	PMID:30420520
Molecular Function	GO:0005515	protein binding	Prmt6	IPI	UniProtKB:Q13227	Mouse	MGI:MGI:5688415|PMID:26070566
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	PRMT6	IDA		Human	PMID:30420520
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	Prmt6	IDA		Mouse	MGI:MGI:5688415|PMID:26070566
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	Prmt6	IDA		Mouse	PMID:18495660
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT6	IDA		Human	PMID:11724789
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT6	IDA		Human	PMID:16157300
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT6	IDA		Human	PMID:17898714
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT6	IDA		Human	PMID:18079182
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT6	IDA		Human	PMID:30420520
Molecular Function	GO:0035241	protein-arginine omega-N monomethyltransferase activity	PRMT6	IDA		Human	PMID:11724789
Molecular Function	GO:0035241	protein-arginine omega-N monomethyltransferase activity	PRMT6	IDA		Human	PMID:16157300
Molecular Function	GO:0035241	protein-arginine omega-N monomethyltransferase activity	PRMT6	IDA		Human	PMID:16600869
Cellular Component	GO:0000785	chromatin	prmt6	IDA		Zfish	PMID:26487724
Cellular Component	GO:0005730	nucleolus	PRMT6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PRMT6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PRMT6	IDA		Human	PMID:11724789
Biological Process	GO:0090398	cellular senescence	Prmt6	IMP		Mouse	PMID:22904064
Biological Process	GO:0021782	glial cell development	prmt6	IMP	ZFIN:ZDB-CRISPR-191009-17,ZFIN:ZDB-CRISPR-191009-18	Zfish	PMID:30924555
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	PRMT6	IDA		Human	PMID:18079182
Biological Process	GO:0010629	negative regulation of gene expression	prmt6	IMP	ZFIN:ZDB-MRPHLNO-141215-14	Zfish	PMID:26487724
Biological Process	GO:0051572	negative regulation of histone H3-K4 methylation	prmt6	IMP	ZFIN:ZDB-MRPHLNO-141215-14	Zfish	PMID:26487724
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Prmt6	IMP		Mouse	PMID:22904064
Biological Process	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	Prmt6	IDA		Mouse	MGI:MGI:5688415|PMID:26070566
Biological Process	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	PRMT6	IDA		Human	PMID:17898714
Biological Process	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	PRMT6	IDA		Human	PMID:18079182
Biological Process	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	PRMT6	IDA		Human	PMID:30420520
Biological Process	GO:0036211	protein modification process	PRMT6	IDA		Human	PMID:30420520
Biological Process	GO:0010821	regulation of mitochondrion organization	PRMT6	IDA		Human	PMID:30420520
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	Prmt6	IMP		Mouse	PMID:22904064
Biological Process	GO:0060041	retina development in camera-type eye	prmt6	IMP	ZFIN:ZDB-CRISPR-191009-17,ZFIN:ZDB-CRISPR-191009-18	Zfish	PMID:30924555

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern