Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRMT8
  • Mouse genes Prmt8
  • Rat genes Prmt8
  • Zfish genes prmt8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prmt8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016273	arginine N-methyltransferase activity	prmt8b	IDA		Zfish	PMID:23554853
Molecular Function	GO:0016273	arginine N-methyltransferase activity	prmt8b	IMP	ZFIN:ZDB-MRPHLNO-130509-2	Zfish	PMID:23554853
Molecular Function	GO:0019899	enzyme binding	PRMT8	IDA		Human	PMID:16051612
Molecular Function	GO:0008469	histone arginine N-methyltransferase activity	PRMT8	IDA		Human	PMID:16051612
Molecular Function	GO:0042802	identical protein binding	PRMT8	IPI	UniProtKB:Q9NR22	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	PRMT8	IPI	UniProtKB:Q9NR22	Human	PMID:19060904
Molecular Function	GO:0042802	identical protein binding	PRMT8	IPI	UniProtKB:Q9NR22	Human	PMID:23455924
Molecular Function	GO:0042802	identical protein binding	PRMT8	IDA		Human	PMID:26876602
Molecular Function	GO:0042802	identical protein binding	PRMT8	IPI	UniProtKB:Q9NR22	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:Q99873	Human	PMID:16051612
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:P06241	Human	PMID:17925405
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:P55345	Human	PMID:17925405
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:Q01844	Human	PMID:18320585
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:O60506	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:O60506	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:Q99873	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:O60506	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:O14787-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:O60506-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:Q99873-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRMT8	IPI	UniProtKB:Q9BZL1	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	PRMT8	IPI	UniProtKB:Q9NR22	Human	PMID:16051612
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT8	IDA		Human	PMID:16051612
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT8	IDA		Human	PMID:17925405
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PRMT8	IDA		Human	PMID:18320585
Molecular Function	GO:0035241	protein-arginine omega-N monomethyltransferase activity	PRMT8	IDA		Human	PMID:16051612
Molecular Function	GO:0035241	protein-arginine omega-N monomethyltransferase activity	PRMT8	IDA		Human	PMID:17925405
Molecular Function	GO:0035241	protein-arginine omega-N monomethyltransferase activity	PRMT8	IDA		Human	PMID:18320585
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	PRMT8	IDA		Human	PMID:26876602
Molecular Function	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	PRMT8	IDA		Human	PMID:16051612
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	PRMT8	IDA		Human	PMID:26876602
Cellular Component	GO:0005886	plasma membrane	PRMT8	IDA		Human	PMID:16051612
Cellular Component	GO:0005886	plasma membrane	PRMT8	IDA		Human	PMID:18320585
Biological Process	GO:0043009	chordate embryonic development	prmt8b	IMP	ZFIN:ZDB-MRPHLNO-130509-2	Zfish	PMID:23554853
Biological Process	GO:0048813	dendrite morphogenesis	prmt8b	IMP	ZFIN:ZDB-MRPHLNO-160318-1	Zfish	PMID:26665171
Biological Process	GO:0048813	dendrite morphogenesis	prmt8b	IMP	ZFIN:ZDB-GENO-160329-1	Zfish	PMID:26665171
Biological Process	GO:0048813	dendrite morphogenesis	prmt8b	IMP	ZFIN:ZDB-MRPHLNO-130509-1	Zfish	PMID:26665171
Biological Process	GO:0016571	histone methylation	PRMT8	IDA		Human	PMID:16051612
Biological Process	GO:0030917	midbrain-hindbrain boundary development	prmt8b	IMP	ZFIN:ZDB-MRPHLNO-130509-1	Zfish	PMID:26665171
Biological Process	GO:0030917	midbrain-hindbrain boundary development	prmt8b	IMP	ZFIN:ZDB-GENO-160329-1	Zfish	PMID:26665171
Biological Process	GO:0048666	neuron development	prmt8b	IMP	ZFIN:ZDB-MRPHLNO-130509-2	Zfish	PMID:23554853
Biological Process	GO:0018216	peptidyl-arginine methylation	PRMT8	IDA		Human	PMID:16051612
Biological Process	GO:0018216	peptidyl-arginine methylation	PRMT8	IDA		Human	PMID:18320585
Biological Process	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	PRMT8	IDA		Human	PMID:16051612
Biological Process	GO:0051260	protein homooligomerization	PRMT8	IDA		Human	PMID:26876602
Biological Process	GO:0006479	protein methylation	PRMT8	IMP		Human	PMID:26876602

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern