Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PROM1
  • Mouse genes Prom1
  • Rat genes Prom1
  • Zfish genes prom1a,prom1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prom1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042805	actinin binding	PROM1	IDA		Human	PMID:18654668
Molecular Function	GO:0045296	cadherin binding	PROM1	IPI	UniProtKB:Q8VHP6	Human	PMID:18654668
Molecular Function	GO:0005515	protein binding	PROM1	IPI	UniProtKB:Q8VHP6	Human	PMID:18654668
Molecular Function	GO:0005515	protein binding	PROM1	IPI	UniProtKB:Q9UBN7	Human	PMID:23084749
Molecular Function	GO:0005515	protein binding	PROM1	IPI	UniProtKB:Q9UHE5	Human	PMID:24556617
Molecular Function	GO:0005515	protein binding	PROM1	IPI	UniProtKB:Q9UHF3	Human	PMID:24556617
Cellular Component	GO:0016324	apical plasma membrane	Prom1	IDA		Mouse	MGI:MGI:4938266|PMID:17109118
Cellular Component	GO:0016324	apical plasma membrane	Prom1	IDA		Mouse	PMID:16892058
Cellular Component	GO:0016324	apical plasma membrane	prom1b	IDA		Zfish	PMID:22492354
Cellular Component	GO:0005903	brush border	Prom1	IDA		Mouse	PMID:9356465
Cellular Component	GO:0042995	cell projection	Prom1	IDA		Mouse	PMID:10587575
Cellular Component	GO:0009986	cell surface	PROM1	IDA		Human	PMID:16809613
Cellular Component	GO:0009986	cell surface	PROM1	IDA		Human	PMID:19384922
Cellular Component	GO:0005929	cilium	Prom1	IDA		Mouse	MGI:MGI:4938266|PMID:17109118
Cellular Component	GO:0005783	endoplasmic reticulum	PROM1	IDA		Human	PMID:24556617
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	PROM1	IDA		Human	PMID:24556617
Cellular Component	GO:0070062	extracellular exosome	PROM1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PROM1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PROM1	IDA		Human	PMID:21082674
Cellular Component	GO:0070062	extracellular exosome	PROM1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	PROM1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Prom1	IDA		Mouse	PMID:15976444
Cellular Component	GO:0005902	microvillus	Prom1	IDA		Mouse	PMID:15976444
Cellular Component	GO:0005902	microvillus	Prom1	IDA		Mouse	PMID:9356465
Cellular Component	GO:0001750	photoreceptor outer segment	Prom1	IDA		Mouse	MGI:MGI:3838023|PMID:19228982
Cellular Component	GO:0042622	photoreceptor outer segment membrane	PROM1	IDA		Human	PMID:18654668
Cellular Component	GO:0005886	plasma membrane	PROM1	IDA		Human	PMID:24556617
Cellular Component	GO:0005886	plasma membrane	Prom1	IDA		Mouse	PMID:9356465
Cellular Component	GO:0071914	prominosome	Prom1	IDA		Mouse	MGI:MGI:4887330|PMID:17283184
Cellular Component	GO:0071914	prominosome	Prom1	IDA		Mouse	MGI:MGI:4938266|PMID:17109118
Cellular Component	GO:0071914	prominosome	Prom1	IDA		Mouse	MGI:MGI:3584059|PMID:15976444
Cellular Component	GO:0032420	stereocilium	Prom1	IDA		Mouse	PMID:15316084
Cellular Component	GO:0031982	vesicle	PROM1	HDA		Human	PMID:19190083
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	PROM1	IMP		Human	PMID:18654668
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	Prom1	IMP		Mouse	MGI:MGI:3838023|PMID:19228982
Biological Process	GO:0072139	glomerular parietal epithelial cell differentiation	PROM1	IMP		Human	PMID:19092120
Biological Process	GO:0045494	photoreceptor cell maintenance	PROM1	IMP		Human	PMID:18654668
Biological Process	GO:0035845	photoreceptor cell outer segment organization	prom1b	IMP	ZFIN:ZDB-GENO-200511-1	Zfish	PMID:31362982
Biological Process	GO:0072112	podocyte differentiation	PROM1	IMP		Human	PMID:19092120
Biological Process	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	PROM1	IMP		Human	PMID:16885410
Biological Process	GO:0010842	retina layer formation	Prom1	IMP		Mouse	MGI:MGI:3838023|PMID:19228982
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	PROM1	IMP		Human	PMID:18654668

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern