Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRPF4
  • Mouse genes Prpf4
  • Rat genes Prpf4
  • Zfish genes prpf4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prpf4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:O43447	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:O43447	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:O43447	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:Q92917	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:P52298,UniProtKB:Q09161	Human	PMID:23793891
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:O43395	Human	PMID:25383878
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:O43447	Human	PMID:25383878
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:Q03468	Human	PMID:26030138
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:O43447	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	PRPF4	IPI	UniProtKB:O43447	Human	PMID:9570313
Cellular Component	GO:0015030	Cajal body	PRPF4	IDA		Human	PMID:15257298
Cellular Component	GO:0016607	nuclear speck	PRPF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	PRPF4	IDA		Human	PMID:25383878
Cellular Component	GO:0005634	nucleus	PRPF4	IDA		Human	PMID:28781166
Cellular Component	GO:0097525	spliceosomal snRNP complex	PRPF4	IDA		Human	PMID:25383878
Cellular Component	GO:0071005	U2-type precatalytic spliceosome	PRPF4	IDA		Human	PMID:28781166
Cellular Component	GO:0071001	U4/U6 snRNP	PRPF4	IDA		Human	PMID:25383878
Cellular Component	GO:0071001	U4/U6 snRNP	PRPF4	IDA		Human	PMID:9570313
Cellular Component	GO:0046540	U4/U6 x U5 tri-snRNP complex	PRPF4	IPI		Human	PMID:30975767
Cellular Component	GO:0046540	U4/U6 x U5 tri-snRNP complex	PRPF4	IDA		Human	PMID:23793891
Biological Process	GO:0043009	chordate embryonic development	prpf4	IMP	ZFIN:ZDB-MRPHLNO-110124-3	Zfish	PMID:24419317
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	prpf4	IMP	ZFIN:ZDB-MRPHLNO-110124-3	Zfish	PMID:25383878
Biological Process	GO:0000398	mRNA splicing, via spliceosome	PRPF4	IDA		Human	PMID:28781166
Biological Process	GO:0000398	mRNA splicing, via spliceosome	prpf4	IMP	ZFIN:ZDB-GENO-190409-2	Zfish	PMID:30174136
Biological Process	GO:0048919	posterior lateral line neuromast development	prpf4	IMP	ZFIN:ZDB-GENO-190409-2	Zfish	PMID:30174136
Biological Process	GO:0048920	posterior lateral line neuromast primordium migration	prpf4	IMP	ZFIN:ZDB-GENO-190409-2	Zfish	PMID:30174136
Biological Process	GO:0060041	retina development in camera-type eye	prpf4	IMP	ZFIN:ZDB-MRPHLNO-110124-3	Zfish	PMID:21051334

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern