Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRPF40A
  • Mouse genes Prpf40a
  • Rat genes Prpf40a
  • Zfish genes prpf40a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prpf40a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070064	proline-rich region binding	Prpf40a	IDA		Mouse	PMID:17915251
Molecular Function	GO:0005515	protein binding	PRPF40A	IPI	UniProtKB:P42858	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	PRPF40A	IPI	UniProtKB:Q12873	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	PRPF40A	IPI	UniProtKB:P42858	Human	PMID:17161366
Molecular Function	GO:0005515	protein binding	PRPF40A	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	PRPF40A	IPI	UniProtKB:Q15459	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	PRPF40A	IPI	UniProtKB:Q8N5F7	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	PRPF40A	IPI	UniProtKB:Q15637	Human	PMID:26420826
Molecular Function	GO:0005515	protein binding	Prpf40a	IPI	PR:Q6ZPF4	Mouse	PMID:9171351
Molecular Function	GO:0005515	protein binding	Prpf40a	IPI	UniProtKB:Q9ULX6	Mouse	PMID:16391387
Molecular Function	GO:0003723	RNA binding	PRPF40A	HDA		Human	PMID:22681889
Cellular Component	GO:0016020	membrane	PRPF40A	HDA		Human	PMID:19946888
Cellular Component	GO:0016363	nuclear matrix	PRPF40A	IDA		Human	PMID:16391387
Cellular Component	GO:0016363	nuclear matrix	Prpf40a	IDA		Mouse	MGI:MGI:4461129|PMID:16391387
Cellular Component	GO:0016607	nuclear speck	PRPF40A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Prpf40a	IDA		Mouse	PMID:11092755
Biological Process	GO:0016477	cell migration	PRPF40A	IMP		Human	PMID:21834987
Biological Process	GO:0007010	cytoskeleton organization	PRPF40A	IMP		Human	PMID:21834987
Biological Process	GO:0008360	regulation of cell shape	PRPF40A	IMP		Human	PMID:21834987
Biological Process	GO:0032465	regulation of cytokinesis	PRPF40A	IMP		Human	PMID:21834987

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern