Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRPF6
  • Mouse genes Prpf6
  • Rat genes Prpf6
  • Zfish genes prpf6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prpf6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	PRPF6	IPI	UniProtKB:O94906	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:P10398	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O95400	Human	PMID:15840814
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O43290	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O43395	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O75643	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:P83876	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:Q6P2Q9	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:Q8WWY3	Human	PMID:16723661
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O95400	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:Q13123	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:Q8WWY3	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O75643	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O95400	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:Q6P2Q9	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O43395	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:O95400	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:P83876	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRPF6	IPI	UniProtKB:P35226	Human	PMID:34316702
Molecular Function	GO:0043021	ribonucleoprotein complex binding	PRPF6	IDA		Human	PMID:10788320
Molecular Function	GO:0003723	RNA binding	PRPF6	IDA		Human	PMID:20797886
Molecular Function	GO:0003723	RNA binding	PRPF6	HDA		Human	PMID:22658674
Cellular Component	GO:0071013	catalytic step 2 spliceosome	PRPF6	IDA		Human	PMID:11991638
Cellular Component	GO:0016020	membrane	PRPF6	HDA		Human	PMID:19946888
Cellular Component	GO:0016607	nuclear speck	PRPF6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	PRPF6	IDA		Human	PMID:21549338
Cellular Component	GO:0005634	nucleus	PRPF6	IDA		Human	PMID:16414017
Cellular Component	GO:0005634	nucleus	PRPF6	IDA		Human	PMID:28781166
Cellular Component	GO:0071005	U2-type precatalytic spliceosome	PRPF6	IDA		Human	PMID:28781166
Cellular Component	GO:0046540	U4/U6 x U5 tri-snRNP complex	PRPF6	IPI		Human	PMID:30975767
Cellular Component	GO:0046540	U4/U6 x U5 tri-snRNP complex	PRPF6	IDA		Human	PMID:10788320
Cellular Component	GO:0005682	U5 snRNP	PRPF6	IDA		Human	PMID:10788320
Biological Process	GO:0000398	mRNA splicing, via spliceosome	PRPF6	IDA		Human	PMID:21549338
Biological Process	GO:0000398	mRNA splicing, via spliceosome	PRPF6	IDA		Human	PMID:28781166
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PRPF6	IDA		Human	PMID:16414017
Biological Process	GO:0006403	RNA localization	PRPF6	IMP		Human	PMID:20797886
Biological Process	GO:0000244	spliceosomal tri-snRNP complex assembly	PRPF6	IMP		Human	PMID:15257298

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern