Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRPS2
  • Mouse genes Prps2
  • Rat genes Prps2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prps2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043531	ADP binding	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Molecular Function	GO:0043531	ADP binding	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Molecular Function	GO:0016208	AMP binding	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Molecular Function	GO:0016208	AMP binding	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Molecular Function	GO:0016208	AMP binding	Prps2	IDA		Rat	PMID:9748490|RGD:1599724
Molecular Function	GO:0005524	ATP binding	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Molecular Function	GO:0005524	ATP binding	Prps2	IDA		Rat	PMID:2546925|RGD:5134985
Molecular Function	GO:0005524	ATP binding	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Molecular Function	GO:0005524	ATP binding	Prps2	IDA		Rat	PMID:9748490|RGD:1599724
Molecular Function	GO:0030246	carbohydrate binding	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Molecular Function	GO:0030246	carbohydrate binding	Prps2	IDA		Rat	PMID:2546925|RGD:5134985
Molecular Function	GO:0030246	carbohydrate binding	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Molecular Function	GO:0030246	carbohydrate binding	Prps2	IDA		Rat	PMID:9748490|RGD:1599724
Molecular Function	GO:0019003	GDP binding	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Molecular Function	GO:0019003	GDP binding	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Molecular Function	GO:0019003	GDP binding	Prps2	IDA		Rat	PMID:9748490|RGD:1599724
Molecular Function	GO:0042802	identical protein binding	PRPS2	IPI	UniProtKB:P11908	Human	PMID:25416956
Molecular Function	GO:0000287	magnesium ion binding	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Molecular Function	GO:0000287	magnesium ion binding	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Molecular Function	GO:0000287	magnesium ion binding	Prps2	IDA		Rat	PMID:9748490|RGD:1599724
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:P60891	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:Q14558	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:Q96HA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:P60891	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:P60891	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:P02766	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:P60891	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PRPS2	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Prps2	IPI	RGD:620206	Rat	PMID:9366267|RGD:5134981
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	Prps2	IDA		Mouse	PMID:26175007
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	Prps2	IMP		Mouse	PMID:24855946
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	Prps2	IDA		Rat	PMID:2546925|RGD:5134985
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	Prps2	IDA		Rat	PMID:9748490|RGD:1599724
Cellular Component	GO:0005829	cytosol	Prps2	IDA		Mouse	PMID:26175007
Cellular Component	GO:0032991	protein-containing complex	Prps2	IDA		Rat	PMID:2546925|RGD:5134985
Cellular Component	GO:0032991	protein-containing complex	Prps2	IDA		Rat	PMID:9348095|RGD:2291928
Cellular Component	GO:0002189	ribose phosphate diphosphokinase complex	Prps2	IDA		Rat	PMID:2546925|RGD:5134985
Biological Process	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	Prps2	IDA		Mouse	PMID:26175007
Biological Process	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	Prps2	IMP		Mouse	PMID:24855946
Biological Process	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	Prps2	IDA		Rat	PMID:9366267|RGD:5134981
Biological Process	GO:0006167	AMP biosynthetic process	Prps2	IDA		Rat	PMID:2546925|RGD:5134985
Biological Process	GO:0031100	animal organ regeneration	Prps2	IEP		Rat	PMID:2822704|RGD:633743
Biological Process	GO:0009165	nucleotide biosynthetic process	Prps2	IDA		Rat	PMID:9748490|RGD:1599724
Biological Process	GO:0006098	pentose-phosphate shunt	Prps2	IMP		Mouse	PMID:24855946
Biological Process	GO:0019693	ribose phosphate metabolic process	Prps2	IDA		Rat	PMID:1651917|RGD:2291920
Biological Process	GO:0019693	ribose phosphate metabolic process	Prps2	IDA		Rat	PMID:9348095|RGD:2291928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern