Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRR5
  • Mouse genes Prr5
  • Rat genes Prr5
  • Zfish genes prr5a,prr5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prr5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PRR5	IPI	UniProtKB:Q12959	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	PRR5	IPI	UniProtKB:Q12959	Human	PMID:30126976
Cellular Component	GO:0031932	TORC2 complex	PRR5	IPI		Human	PMID:17461779
Cellular Component	GO:0031932	TORC2 complex	PRR5	IDA		Human	PMID:22609986
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	Prr5	IGI	MGI:MGI:1919696	Mouse	PMID:21413931
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	Prr5	IMP		Mouse	PMID:21413931
Biological Process	GO:0016310	phosphorylation	PRR5	IDA		Human	PMID:29567957
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Prr5	IMP		Mouse	PMID:21413931
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Prr5	IGI	MGI:MGI:1919696	Mouse	PMID:21413931
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Prr5	IMP		Mouse	PMID:21413931
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Prr5	IGI	MGI:MGI:1919696	Mouse	PMID:21413931
Biological Process	GO:0006468	protein phosphorylation	Prr5	IMP		Mouse	PMID:21413931
Biological Process	GO:0006468	protein phosphorylation	Prr5	IGI	MGI:MGI:1919696	Mouse	PMID:21413931

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern