Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRTN3
  • Mouse genes Prtn3
  • Rat genes Prtn3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prtn3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	PRTN3	IPI	UniProtKB:O15162	Human	PMID:17712045
Molecular Function	GO:0005515	protein binding	PRTN3	IPI	UniProtKB:P24001-4	Human	PMID:16488976
Molecular Function	GO:0005515	protein binding	PRTN3	IPI	UniProtKB:Q8N6Q3	Human	PMID:28240246
Molecular Function	GO:0005515	protein binding	PRTN3	IPI	UniProtKB:P30740	Human	PMID:30692621
Molecular Function	GO:0005515	protein binding	Prtn3	IPI	PR:P23611	Mouse	PMID:25331958
Molecular Function	GO:0004252	serine-type endopeptidase activity	PRTN3	EXP		Human	PMID:11389039
Molecular Function	GO:0004252	serine-type endopeptidase activity	PRTN3	IMP		Human	PMID:22266279
Molecular Function	GO:0004252	serine-type endopeptidase activity	PRTN3	IMP		Human	PMID:23202369
Molecular Function	GO:0004252	serine-type endopeptidase activity	PRTN3	IDA		Human	PMID:28240246
Molecular Function	GO:0005102	signaling receptor binding	PRTN3	IPI	UniProtKB:Q8N6Q3	Human	PMID:17244676
Cellular Component	GO:0035578	azurophil granule lumen	PRTN3	IDA		Human	PMID:18462208
Cellular Component	GO:0062023	collagen-containing extracellular matrix	PRTN3	HDA		Human	PMID:20551380
Cellular Component	GO:0005829	cytosol	PRTN3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PRTN3	IDA		Human	PMID:17712045
Cellular Component	GO:0070062	extracellular exosome	PRTN3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PRTN3	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	PRTN3	HDA		Human	PMID:16502470
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PRTN3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PRTN3	IDA		Human	PMID:17244676
Cellular Component	GO:0005886	plasma membrane	PRTN3	IDA		Human	PMID:18462208
Cellular Component	GO:0005886	plasma membrane	PRTN3	IDA		Human	PMID:21193407
Cellular Component	GO:0005886	plasma membrane	PRTN3	IDA		Human	PMID:22266279
Cellular Component	GO:0005886	plasma membrane	PRTN3	IDA		Human	PMID:28240246
Cellular Component	GO:0005886	plasma membrane	PRTN3	IDA		Human	PMID:17712045
Cellular Component	GO:0044853	plasma membrane raft	PRTN3	IDA		Human	PMID:21193407
Biological Process	GO:0045217	cell-cell junction maintenance	PRTN3	IMP		Human	PMID:23202369
Biological Process	GO:0097029	mature conventional dendritic cell differentiation	PRTN3	IDA		Human	PMID:16478888
Biological Process	GO:0006509	membrane protein ectodomain proteolysis	PRTN3	IMP		Human	PMID:23202369
Biological Process	GO:0050765	negative regulation of phagocytosis	PRTN3	IDA		Human	PMID:17712045
Biological Process	GO:0072672	neutrophil extravasation	PRTN3	IMP		Human	PMID:22266279
Biological Process	GO:0043547	positive regulation of GTPase activity	PRTN3	IMP		Human	PMID:23202369
Biological Process	GO:0006508	proteolysis	PRTN3	IMP		Human	PMID:22266279
Biological Process	GO:0006508	proteolysis	PRTN3	IDA		Human	PMID:28240246

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern