Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRXL2B
  • Mouse genes Prxl2b
  • Rat genes Prxl2b
  • Zfish genes prxl2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prxl2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Prxl2b	IDA		Mouse	MGI:MGI:3771130|PMID:18006499
Molecular Function	GO:0047017	prostaglandin-F synthase activity	Prxl2b	IMP		Mouse	MGI:MGI:3771130|PMID:18006499
Molecular Function	GO:0005515	protein binding	PRXL2B	IPI	UniProtKB:Q9NUJ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRXL2B	IPI	UniProtKB:Q9UNS2	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Prxl2b	IDA		Mouse	PMID:18006499
Cellular Component	GO:0005829	cytosol	Prxl2b	IDA		Mouse	PMID:18006499
Cellular Component	GO:0005783	endoplasmic reticulum	Prxl2b	IDA		Mouse	MGI:MGI:3771130|PMID:18006499
Cellular Component	GO:0070062	extracellular exosome	PRXL2B	HDA		Human	PMID:19056867
Cellular Component	GO:0043209	myelin sheath	Prxl2b	IDA		Mouse	MGI:MGI:5545989|PMID:20950588
Cellular Component	GO:0043209	myelin sheath	Prxl2b	IDA		Rat	PMID:20950588|RGD:8554513
Biological Process	GO:0001516	prostaglandin biosynthetic process	Prxl2b	IDA		Mouse	MGI:MGI:3771130|PMID:18006499

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern