Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PSMB8
  • Mouse genes Psmb8
  • Rat genes Psmb8
  • Zfish genes psmb8a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Psmb8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PSMB8	IPI	UniProtKB:P27958:PRO_0000037573	Human	PMID:15303969
Molecular Function	GO:0005515	protein binding	Psmb8	IPI	PR:Q8BWR2	Mouse	PMID:31915251
Cellular Component	GO:0070062	extracellular exosome	PSMB8	HDA		Human	PMID:20458337
Cellular Component	GO:0000502	proteasome complex	PSMB8	IDA		Human	PMID:26524591
Cellular Component	GO:0005839	proteasome core complex	Psmb8	IDA		Mouse	MGI:MGI:5442509|PMID:16857966
Cellular Component	GO:0005839	proteasome core complex	Psmb8	IDA		Mouse	PMID:17540904
Cellular Component	GO:1990111	spermatoproteasome complex	Psmb8	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Biological Process	GO:0019882	antigen processing and presentation	Psmb8	IMP	MGI:MGI:3055222	Mouse	PMID:15356141
Biological Process	GO:0045444	fat cell differentiation	PSMB8	IMP		Human	PMID:21881205
Biological Process	GO:0045444	fat cell differentiation	Psmb8	IMP		Mouse	MGI:MGI:5294892|PMID:21881205
Biological Process	GO:0052548	regulation of endopeptidase activity	PSMB8	IMP		Human	PMID:26524591

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern