Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PSME4
  • Mouse genes Psme4
  • Rat genes Psme4
  • Zfish genes psme4a,psme4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Psme4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070577	lysine-acetylated histone binding	Psme4	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Molecular Function	GO:0016504	peptidase activator activity	Psme4	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Molecular Function	GO:0005515	protein binding	PSME4	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PSME4	IPI	UniProtKB:Q86Y26	Human	PMID:25416956
Cellular Component	GO:0005829	cytosol	Psme4	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Cellular Component	GO:0005654	nucleoplasm	PSME4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PSME4	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Psme4	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Cellular Component	GO:1990111	spermatoproteasome complex	Psme4	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Biological Process	GO:0006974	DNA damage response	Psme4	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Biological Process	GO:0006281	DNA repair	Psme4	IMP		Mouse	MGI:MGI:5494329|PMID:23706739
Biological Process	GO:0010499	proteasomal ubiquitin-independent protein catabolic process	Psme4	IDA		Mouse	MGI:MGI:5494329|PMID:23706739
Biological Process	GO:0035092	sperm DNA condensation	Psme4	IMP		Mouse	MGI:MGI:5494329|PMID:23706739

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern