Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PSRC1
  • Mouse genes Psrc1
  • Rat genes Psrc1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Psrc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	Psrc1	IDA		Mouse	MGI:MGI:3773778|PMID:17310996
Molecular Function	GO:0005515	protein binding	PSRC1	IPI	UniProtKB:O00139	Human	PMID:18411309
Molecular Function	GO:0005515	protein binding	PSRC1	IPI	UniProtKB:Q8N9V6	Human	PMID:26820536
Molecular Function	GO:0005515	protein binding	PSRC1	IPI	UniProtKB:Q9UPY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Psrc1	IPI	UniProtKB:Q6PER3	Mouse	MGI:MGI:3773778|PMID:17310996
Cellular Component	GO:0005737	cytoplasm	Psrc1	IDA		Mouse	MGI:MGI:1891485|PMID:10618717
Cellular Component	GO:0005737	cytoplasm	Psrc1	IDA		Mouse	MGI:MGI:3773778|PMID:17310996
Cellular Component	GO:0005829	cytosol	PSRC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PSRC1	IDA		Human	PMID:18411309
Cellular Component	GO:0015630	microtubule cytoskeleton	Psrc1	IDA		Mouse	MGI:MGI:3773778|PMID:17310996
Cellular Component	GO:0030496	midbody	Psrc1	IDA		Mouse	MGI:MGI:3773778|PMID:17310996
Cellular Component	GO:0005654	nucleoplasm	PSRC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005819	spindle	Psrc1	IDA		Mouse	MGI:MGI:3773778|PMID:17310996
Cellular Component	GO:0005876	spindle microtubule	PSRC1	IDA		Human	PMID:18411309
Cellular Component	GO:0000922	spindle pole	PSRC1	IDA		Human	PMID:18411309
Biological Process	GO:0001578	microtubule bundle formation	Psrc1	IDA		Mouse	MGI:MGI:3773778|PMID:17310996
Biological Process	GO:0007080	mitotic metaphase plate congression	PSRC1	IDA		Human	PMID:18411309
Biological Process	GO:0030308	negative regulation of cell growth	Psrc1	IMP		Mouse	MGI:MGI:1891485|PMID:10618717
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	Psrc1	IMP		Mouse	MGI:MGI:3773778|PMID:17310996
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Psrc1	IMP		Mouse	MGI:MGI:3773778|PMID:17310996
Biological Process	GO:0031116	positive regulation of microtubule polymerization	Psrc1	IDA		Mouse	MGI:MGI:3773778|PMID:17310996
Biological Process	GO:0060236	regulation of mitotic spindle organization	PSRC1	IDA		Human	PMID:18411309

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern