Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTAFR
  • Mouse genes Ptafr
  • Rat genes Ptafr
  • Zfish genes ptafr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptafr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001530	lipopolysaccharide binding	Ptafr	IMP		Mouse	PMID:9013981
Molecular Function	GO:0001875	lipopolysaccharide immune receptor activity	Ptafr	IMP		Mouse	PMID:9013981
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	Ptafr	IDA		Rat	PMID:23911909|RGD:8657085
Molecular Function	GO:0005543	phospholipid binding	PTAFR	IDA		Human	PMID:1656963
Molecular Function	GO:0005543	phospholipid binding	PTAFR	IDA		Human	PMID:1657923
Molecular Function	GO:0004992	platelet activating factor receptor activity	PTAFR	IDA		Human	PMID:1281995
Molecular Function	GO:0004992	platelet activating factor receptor activity	PTAFR	IDA		Human	PMID:1656963
Molecular Function	GO:0004992	platelet activating factor receptor activity	PTAFR	IDA		Human	PMID:1657923
Molecular Function	GO:0004992	platelet activating factor receptor activity	Ptafr	IDA		Rat	PMID:8798508|RGD:9999203
Molecular Function	GO:0005515	protein binding	PTAFR	IPI	UniProtKB:Q05397	Human	PMID:20576130
Molecular Function	GO:0005515	protein binding	Ptafr	IPI	RGD:2157	Rat	PMID:23911909|RGD:8657085
Cellular Component	GO:0016020	membrane	Ptafr	IDA		Rat	PMID:9495811|RGD:9999209
Cellular Component	GO:0005886	plasma membrane	Ptafr	IDA		Rat	PMID:8825027|RGD:9999201
Biological Process	GO:1904317	cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	Ptafr	IEP		Rat	PMID:9321918|RGD:10041061
Biological Process	GO:0071320	cellular response to cAMP	Ptafr	IEP		Rat	PMID:2170386|RGD:9999223
Biological Process	GO:0071398	cellular response to fatty acid	Ptafr	IEP		Rat	PMID:17515866|RGD:9999208
Biological Process	GO:0071258	cellular response to gravity	Ptafr	IEP		Rat	PMID:15659787|RGD:9999200
Biological Process	GO:0001816	cytokine production	Ptafr	IMP	MGI:MGI:3036770	Mouse	PMID:14742561
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	PTAFR	IMP		Human	PMID:1657923
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Ptafr	IMP		Rat	PMID:9495811|RGD:9999209
Biological Process	GO:0006954	inflammatory response	Ptafr	IMP	MGI:MGI:3036770	Mouse	PMID:14742561
Biological Process	GO:0032959	inositol trisphosphate biosynthetic process	Ptafr	IMP		Mouse	PMID:9013981
Biological Process	GO:0045776	negative regulation of blood pressure	Ptafr	IMP		Rat	PMID:3019921|RGD:10043185
Biological Process	GO:0045776	negative regulation of blood pressure	Ptafr	IMP		Rat	PMID:9548392|RGD:10041048
Biological Process	GO:0007567	parturition	Ptafr	IMP		Rat	PMID:1849751|RGD:10041055
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	PTAFR	IDA		Human	PMID:1657923
Biological Process	GO:0002693	positive regulation of cellular extravasation	Ptafr	IMP		Rat	PMID:2829894|RGD:10041060
Biological Process	GO:0002693	positive regulation of cellular extravasation	Ptafr	IMP		Rat	PMID:3011900|RGD:10043179
Biological Process	GO:1904306	positive regulation of gastro-intestinal system smooth muscle contraction	Ptafr	IMP		Rat	PMID:10821044|RGD:10043148
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	Ptafr	IDA		Rat	PMID:8798508|RGD:9999203
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Ptafr	IMP		Rat	PMID:11779582|RGD:10043184
Biological Process	GO:1903039	positive regulation of leukocyte cell-cell adhesion	Ptafr	IMP		Rat	PMID:8592427|RGD:10041047
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	Ptafr	IMP		Rat	PMID:10528212|RGD:10041051
Biological Process	GO:1904303	positive regulation of maternal process involved in parturition	Ptafr	IMP		Rat	PMID:1849751|RGD:10041055
Biological Process	GO:0043315	positive regulation of neutrophil degranulation	Ptafr	IMP		Rat	PMID:2829894|RGD:10041060
Biological Process	GO:0010863	positive regulation of phospholipase C activity	Ptafr	IDA		Rat	PMID:8798508|RGD:9999203
Biological Process	GO:1904058	positive regulation of sensory perception of pain	Ptafr	IMP		Rat	PMID:19283893|RGD:5129125
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Ptafr	IMP		Rat	PMID:8216700|RGD:10043166
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	Ptafr	IMP		Rat	PMID:10821044|RGD:10043148
Biological Process	GO:1904300	positive regulation of transcytosis	Ptafr	IMP		Rat	PMID:9664076|RGD:10041053
Biological Process	GO:0045727	positive regulation of translation	Ptafr	IMP		Rat	PMID:8216700|RGD:10043166
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Ptafr	IMP		Rat	PMID:2545780|RGD:10043183
Biological Process	GO:1902943	positive regulation of voltage-gated chloride channel activity	Ptafr	IDA		Rat	PMID:8168510|RGD:61717
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ptafr	IMP		Rat	PMID:10482285|RGD:10041056
Biological Process	GO:1904316	response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	Ptafr	IEP		Rat	PMID:9065783|RGD:9999198
Biological Process	GO:0071548	response to dexamethasone	Ptafr	IEP		Rat	PMID:10447766|RGD:9999199
Biological Process	GO:0032496	response to lipopolysaccharide	Ptafr	IMP		Mouse	PMID:9013981
Biological Process	GO:0032496	response to lipopolysaccharide	Ptafr	IEP		Rat	PMID:9065783|RGD:9999198
Biological Process	GO:0046683	response to organophosphorus	Ptafr	IEP		Rat	PMID:9321918|RGD:10041061
Biological Process	GO:0009609	response to symbiotic bacterium	Ptafr	IEP		Rat	PMID:10447766|RGD:9999199
Biological Process	GO:0045056	transcytosis	Ptafr	IMP		Rat	PMID:9664076|RGD:10041053

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern