Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTBP2
  • Mouse genes Ptbp2
  • Rat genes Ptbp2
  • Zfish genes ptbp2a,ptbp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptbp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003729	mRNA binding	Ptbp2	IDA		Mouse	PMID:10829067
Molecular Function	GO:0003729	mRNA binding	Ptbp2	IDA		Mouse	PMID:22802532
Molecular Function	GO:0005515	protein binding	Ptbp2	IPI	UniProtKB:Q9WVE0	Mouse	MGI:MGI:4946885|PMID:21186367
Molecular Function	GO:0005515	protein binding	Ptbp2	IPI	PR:Q9JKN6	Mouse	PMID:10829067
Molecular Function	GO:0003723	RNA binding	PTBP2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PTBP2	HDA		Human	PMID:22681889
Cellular Component	GO:0030426	growth cone	Ptbp2	IDA		Rat	PMID:12038983|RGD:10045956
Cellular Component	GO:0043025	neuronal cell body	Ptbp2	IDA		Rat	PMID:12038983|RGD:10045956
Cellular Component	GO:0005634	nucleus	Ptbp2	IDA		Rat	PMID:11056394|RGD:10045940
Cellular Component	GO:0005681	spliceosomal complex	Ptbp2	IDA		Mouse	PMID:10829067
Biological Process	GO:0021549	cerebellum development	Ptbp2	IEP		Rat	PMID:9917071|RGD:10045971
Biological Process	GO:0006376	mRNA splice site selection	Ptbp2	IDA		Mouse	PMID:10829067
Biological Process	GO:0006376	mRNA splice site selection	Ptbp2	IMP	MGI:MGI:4124189	Mouse	PMID:22802532
Biological Process	GO:0033119	negative regulation of RNA splicing	PTBP2	IDA		Human	PMID:18335065
Biological Process	GO:0033119	negative regulation of RNA splicing	Ptbp2	IMP		Rat	PMID:18534753|RGD:10045970
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	Ptbp2	IMP	MGI:MGI:4124189	Mouse	PMID:22802532
Biological Process	GO:0021510	spinal cord development	Ptbp2	IEP		Rat	PMID:12124753|RGD:708602

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern