Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTCHD1
  • Mouse genes Ptchd1
  • Rat genes Ptchd1
  • Zfish genes ptchd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptchd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Ptchd1	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:6193083|PMID:28416808
Molecular Function	GO:0005515	protein binding	Ptchd1	IPI	PR:Q62108	Mouse	PMID:29118110
Molecular Function	GO:0005515	protein binding	Ptchd1	IPI	PR:Q9EQH3	Mouse	PMID:29118110
Cellular Component	GO:0005886	plasma membrane	PTCHD1	IDA		Human	PMID:20844286
Cellular Component	GO:0045202	synapse	Ptchd1	IMP	MGI:MGI:2176180|MGI:MGI:6111285	Mouse	MGI:MGI:6103329|PMID:29118110
Cellular Component	GO:0045202	synapse	Ptchd1	IDA		Mouse	PMID:29118110
Biological Process	GO:0050890	cognition	PTCHD1	IMP		Human	PMID:20844286
Biological Process	GO:0050890	cognition	Ptchd1	IMP		Mouse	MGI:MGI:5779981|PMID:27007844
Biological Process	GO:0098976	excitatory chemical synaptic transmission	Ptchd1	IMP	MGI:MGI:2176180,MGI:MGI:6111285	Mouse	PMID:29118110
Biological Process	GO:0098977	inhibitory chemical synaptic transmission	Ptchd1	IMP	MGI:MGI:2176180,MGI:MGI:6111285	Mouse	PMID:29118110
Biological Process	GO:0007616	long-term memory	Ptchd1	IMP	MGI:MGI:2176180,MGI:MGI:6111285	Mouse	PMID:29118110
Biological Process	GO:0007614	short-term memory	Ptchd1	IMP	MGI:MGI:2176180,MGI:MGI:6111285	Mouse	PMID:29118110
Biological Process	GO:0007224	smoothened signaling pathway	PTCHD1	IDA		Human	PMID:20844286
Biological Process	GO:0035176	social behavior	Ptchd1	IMP		Mouse	MGI:MGI:5779981|PMID:27007844
Biological Process	GO:0021794	thalamus development	Ptchd1	IMP		Mouse	MGI:MGI:5779981|PMID:27007844

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern