Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTGDR
  • Mouse genes Ptgdr
  • Rat genes Ptgdr,Ptgdrl1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptgdr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004956	prostaglandin D receptor activity	Ptgdr	IDA		Mouse	PMID:12878180
Molecular Function	GO:0004956	prostaglandin D receptor activity	Ptgdr	IDA		Rat	PMID:10448933|RGD:633864
Molecular Function	GO:0001785	prostaglandin J receptor activity	Ptgdr	IDA		Mouse	PMID:12878180
Molecular Function	GO:0005515	protein binding	PTGDR	IPI	UniProtKB:Q8N6S4	Human	PMID:20959461
Cellular Component	GO:0016020	membrane	Ptgdr	IDA		Rat	PMID:10448933|RGD:633864
Cellular Component	GO:0005886	plasma membrane	PTGDR	IDA		Human	PMID:20959461
Cellular Component	GO:0005886	plasma membrane	Ptgdr	IDA		Mouse	PMID:11562489
Biological Process	GO:0046085	adenosine metabolic process	Ptgdr	IMP	MGI:MGI:2386956	Mouse	PMID:11562489
Biological Process	GO:0071799	cellular response to prostaglandin D stimulus	Ptgdr	IMP	MGI:MGI:2386956	Mouse	PMID:11562489
Biological Process	GO:0006954	inflammatory response	Ptgdr	IMP	MGI:MGI:2386956	Mouse	PMID:15834430
Biological Process	GO:0030238	male sex determination	Ptgdr	IMP		Mouse	PMID:16185683
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	Ptgdr	IMP		Rat	PMID:19576888|RGD:2316816
Biological Process	GO:0060406	positive regulation of penile erection	Ptgdr	IDA		Rat	PMID:18047485|RGD:2316817
Biological Process	GO:0030431	sleep	Ptgdr	IMP	MGI:MGI:2386956	Mouse	PMID:11562489
Biological Process	GO:0042311	vasodilation	Ptgdr	IMP		Rat	PMID:17643322|RGD:2316818

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern