Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTGDS
  • Mouse genes Ptgds
  • Rat genes Ptgds
  • Zfish genes lcn15,ptgdsa,ptgdsb.1,ptgdsb.2,zgc:153704
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptgds

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005504	fatty acid binding	PTGDS	IDA		Human	PMID:20667974
Molecular Function	GO:0004667	prostaglandin-D synthase activity	PTGDS	IDA		Human	PMID:20347284
Molecular Function	GO:0004667	prostaglandin-D synthase activity	PTGDS	IDA		Human	PMID:20667974
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Ptgds	IDA		Mouse	MGI:MGI:3761957|PMID:17715133
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Ptgds	IDA		Rat	PMID:7836410|RGD:8553429
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:Q9BWT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PTGDS	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0001972	retinoic acid binding	ptgdsb.1	IDA		Zfish	PMID:16616995
Molecular Function	GO:0005501	retinoid binding	Ptgds	IDA		Mouse	MGI:MGI:3761957|PMID:17715133
Molecular Function	GO:0005501	retinoid binding	Ptgds	IDA		Rat	PMID:9188476|RGD:8553602
Cellular Component	GO:0070062	extracellular exosome	PTGDS	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	PTGDS	IDA		Human	PMID:7692978
Cellular Component	GO:0005576	extracellular region	Ptgds	IDA		Mouse	MGI:MGI:84013|PMID:8922532
Cellular Component	GO:0005576	extracellular region	Ptgds	IDA		Rat	PMID:8815894|RGD:8553670
Cellular Component	GO:0005615	extracellular space	PTGDS	IDA		Human	PMID:19878301
Cellular Component	GO:0005615	extracellular space	Ptgds	IDA		Rat	PMID:17259069|RGD:1642585
Cellular Component	GO:0005794	Golgi apparatus	Ptgds	IDA		Rat	PMID:11058225|RGD:8553859
Cellular Component	GO:0005791	rough endoplasmic reticulum	PTGDS	IDA		Human	PMID:9065498
Biological Process	GO:0010467	gene expression	Ptgds	IMP		Mouse	PMID:26025376
Biological Process	GO:0010467	gene expression	Ptgds	IDA		Mouse	PMID:26025376
Biological Process	GO:2000255	negative regulation of male germ cell proliferation	Ptgds	IGI	MGI:MGI:1859384	Mouse	PMID:25142465
Biological Process	GO:0001516	prostaglandin biosynthetic process	PTGDS	IDA		Human	PMID:20347284
Biological Process	GO:0001516	prostaglandin biosynthetic process	PTGDS	IDA		Human	PMID:20667974
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptgds	IDA		Mouse	MGI:MGI:3761957|PMID:17715133
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptgds	IDA		Rat	PMID:7836410|RGD:8553429
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	Ptgds	IDA		Mouse	MGI:MGI:3687807|PMID:10781097
Biological Process	GO:0051384	response to glucocorticoid	Ptgds	IEP		Rat	PMID:14618091|RGD:1642583

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern