Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTGER3
  • Mouse genes Ptger3
  • Rat genes Ptger3
  • Zfish genes ptger3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptger3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004957	prostaglandin E receptor activity	Ptger3	IDA		Mouse	PMID:8223569
Molecular Function	GO:0004957	prostaglandin E receptor activity	Ptger3	IMP		Mouse	PMID:7733888
Molecular Function	GO:0004957	prostaglandin E receptor activity	Ptger3	IDA		Mouse	PMID:8076637
Molecular Function	GO:0004957	prostaglandin E receptor activity	Ptger3	IDA		Mouse	PMID:7945376
Molecular Function	GO:0004957	prostaglandin E receptor activity	Ptger3	IDA		Rat	PMID:10336471|RGD:9850259
Molecular Function	GO:0004957	prostaglandin E receptor activity	Ptger3	IMP		Rat	PMID:9350980|RGD:9850278
Molecular Function	GO:0004957	prostaglandin E receptor activity	ptger3	IDA		Zfish	PMID:23892039
Molecular Function	GO:0005515	protein binding	Ptger3	IPI	PR:P08752	Mouse	PMID:8076637
Cellular Component	GO:0031526	brush border membrane	Ptger3	IDA		Rat	PMID:15292051|RGD:10003094
Cellular Component	GO:0009986	cell surface	Ptger3	IDA		Rat	PMID:15937517|RGD:10043344
Cellular Component	GO:0043005	neuron projection	Ptger3	IDA		Rat	PMID:20336467|RGD:9850277
Cellular Component	GO:0043025	neuronal cell body	Ptger3	IDA		Rat	PMID:20336467|RGD:9850277
Cellular Component	GO:0031965	nuclear membrane	Ptger3	IDA		Rat	PMID:10336471|RGD:9850259
Cellular Component	GO:0005886	plasma membrane	PTGER3	IDA		Human	PMID:31097585
Cellular Component	GO:0005886	plasma membrane	Ptger3	IDA		Mouse	PMID:8223569
Cellular Component	GO:0005886	plasma membrane	Ptger3	IDA		Mouse	PMID:8381413
Cellular Component	GO:0005886	plasma membrane	Ptger3	IDA		Rat	PMID:10336471|RGD:9850259
Cellular Component	GO:1990769	proximal neuron projection	Ptger3	IDA		Rat	PMID:21104189|RGD:10045900
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Ptger3	IDA		Mouse	PMID:8223569
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Ptger3	IDA		Mouse	PMID:8381413
Biological Process	GO:0015701	bicarbonate transport	Ptger3	IMP	MGI:MGI:2137759	Mouse	PMID:10535876
Biological Process	GO:1904322	cellular response to forskolin	Ptger3	IMP		Rat	PMID:15937517|RGD:10043344
Biological Process	GO:0071347	cellular response to interleukin-1	Ptger3	IEP		Rat	PMID:16405508|RGD:9850258
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Ptger3	IEP		Rat	PMID:14636300|RGD:10043359
Biological Process	GO:0002029	desensitization of G protein-coupled receptor signaling pathway	Ptger3	IMP		Rat	PMID:9350980|RGD:9850278
Biological Process	GO:0007565	female pregnancy	Ptger3	IEP		Rat	PMID:10819751|RGD:10043343
Biological Process	GO:0001660	fever generation	Ptger3	IDA		Mouse	PMID:9751056
Biological Process	GO:0001660	fever generation	Ptger3	IMP	MGI:MGI:2137759	Mouse	PMID:9751056
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Ptger3	IDA		Mouse	MGI:MGI:69021|PMID:7945376
Biological Process	GO:0014827	intestine smooth muscle contraction	Ptger3	IMP		Rat	PMID:24170253|RGD:10043193
Biological Process	GO:0060836	lymphatic endothelial cell differentiation	ptger3	IMP	ZFIN:ZDB-GENO-200618-1	Zfish	PMID:31114004
Biological Process	GO:0060137	maternal process involved in parturition	Ptger3	IEP		Rat	PMID:19801535|RGD:10043313
Biological Process	GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ptger3	IMP		Rat	PMID:9013884|RGD:9850263
Biological Process	GO:1903170	negative regulation of calcium ion transmembrane transport	Ptger3	IMP		Rat	PMID:10670413|RGD:10043333
Biological Process	GO:1904326	negative regulation of circadian sleep/wake cycle, wakefulness	Ptger3	IMP		Rat	PMID:10923657|RGD:10043386
Biological Process	GO:2000978	negative regulation of forebrain neuron differentiation	Ptger3	IMP		Rat	PMID:19555672|RGD:10043320
Biological Process	GO:0060455	negative regulation of gastric acid secretion	Ptger3	IMP		Rat	PMID:15961884|RGD:10043339
Biological Process	GO:1903640	negative regulation of gastrin-induced gastric acid secretion	Ptger3	IMP		Rat	PMID:15961884|RGD:10043339
Biological Process	GO:0046676	negative regulation of insulin secretion	Ptger3	IDA		Rat	PMID:10531320|RGD:10043332
Biological Process	GO:0010700	negative regulation of norepinephrine secretion	Ptger3	IMP		Rat	PMID:12524145|RGD:10043195
Biological Process	GO:0090331	negative regulation of platelet aggregation	Ptger3	IMP		Rat	PMID:20303752|RGD:10043327
Biological Process	GO:1901380	negative regulation of potassium ion transmembrane transport	Ptger3	IMP		Rat	PMID:18496512|RGD:10043331
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Ptger3	IDA		Mouse	PMID:7945376
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Ptger3	IMP		Rat	PMID:11278900|RGD:10003101
Biological Process	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	Ptger3	IMP		Rat	PMID:10923657|RGD:10043386
Biological Process	GO:1904343	positive regulation of colon smooth muscle contraction	Ptger3	IMP		Rat	PMID:24170253|RGD:10043193
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Ptger3	IDA		Mouse	PMID:7945376
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Ptger3	IMP		Rat	PMID:8743550|RGD:10043347
Biological Process	GO:0031622	positive regulation of fever generation	Ptger3	IMP		Mouse	MGI:MGI:4413614|PMID:19940926
Biological Process	GO:1904346	positive regulation of gastric mucosal blood circulation	Ptger3	IMP		Rat	PMID:10807413|RGD:10043357
Biological Process	GO:0010628	positive regulation of gene expression	Ptger3	IMP		Rat	PMID:17408863|RGD:10043191
Biological Process	GO:1904325	positive regulation of inhibitory G protein-coupled receptor phosphorylation	Ptger3	IMP		Rat	PMID:15937517|RGD:10043344
Biological Process	GO:1904330	positive regulation of myofibroblast contraction	Ptger3	IMP		Rat	PMID:19239477|RGD:10045899
Biological Process	GO:2000391	positive regulation of neutrophil extravasation	Ptger3	IMP		Rat	PMID:15944932|RGD:10003098
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Ptger3	IMP		Rat	PMID:15937517|RGD:10043344
Biological Process	GO:1904320	positive regulation of smooth muscle contraction involved in micturition	Ptger3	IMP		Rat	PMID:18562635|RGD:10043314
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	ptger3	IMP	ZFIN:ZDB-MRPHLNO-170720-1	Zfish	PMID:28254818
Biological Process	GO:0035810	positive regulation of urine volume	Ptger3	IMP	MGI:MGI:2157796	Mouse	PMID:9843913
Biological Process	GO:0045907	positive regulation of vasoconstriction	Ptger3	IMP		Rat	PMID:10747002|RGD:10043337
Biological Process	GO:1990767	prostaglandin receptor internalization	Ptger3	IMP		Rat	PMID:15937517|RGD:10043344
Biological Process	GO:0031623	receptor internalization	Ptger3	IMP		Rat	PMID:15937517|RGD:10043344
Biological Process	GO:0010840	regulation of circadian sleep/wake cycle, wakefulness	Ptger3	IMP		Rat	PMID:10923657|RGD:10043386
Biological Process	GO:0014061	regulation of norepinephrine secretion	Ptger3	IMP		Rat	PMID:12524145|RGD:10043195
Biological Process	GO:1903670	regulation of sprouting angiogenesis	ptger3	IGI	ZFIN:ZDB-GENE-040426-2575,ZFIN:ZDB-GENE-980526-362	Zfish	PMID:28254818
Biological Process	GO:1903670	regulation of sprouting angiogenesis	ptger3	IGI	ZFIN:ZDB-GENE-041014-73	Zfish	PMID:28254818
Biological Process	GO:0032355	response to estradiol	Ptger3	IEP		Rat	PMID:10819751|RGD:10043343
Biological Process	GO:0032496	response to lipopolysaccharide	Ptger3	IMP	MGI:MGI:2137759	Mouse	PMID:15834430
Biological Process	GO:0032570	response to progesterone	Ptger3	IEP		Rat	PMID:19801535|RGD:10043313
Biological Process	GO:1902074	response to salt	Ptger3	IEP		Rat	PMID:10432392|RGD:9850282
Biological Process	GO:0009410	response to xenobiotic stimulus	Ptger3	IEP		Rat	PMID:19801535|RGD:10043313
Biological Process	GO:0014832	urinary bladder smooth muscle contraction	Ptger3	IMP		Rat	PMID:18562635|RGD:10043314

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern