Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTGES
  • Mouse genes Ptges
  • Rat genes Ptges
  • Zfish genes ptges
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptges

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043295	glutathione binding	PTGES	IDA		Human	PMID:18682561
Molecular Function	GO:0004602	glutathione peroxidase activity	PTGES	IDA		Human	PMID:12244105
Molecular Function	GO:0004364	glutathione transferase activity	PTGES	IDA		Human	PMID:12672824
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Ptges	IDA		Mouse	MGI:MGI:6393388|PMID:11795891
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Ptges	IDA		Rat	PMID:10869354|RGD:61719
Molecular Function	GO:0050220	prostaglandin-E synthase activity	PTGES	IDA		Human	PMID:18682561
Molecular Function	GO:0050220	prostaglandin-E synthase activity	Ptges	IDA		Rat	PMID:11067848|RGD:67929
Molecular Function	GO:0050220	prostaglandin-E synthase activity	ptges	IMP	ZFIN:ZDB-MRPHLNO-060220-2	Zfish	PMID:16391234
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:O15155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:O75379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:O95070	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:O95292	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q04941	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q6PI78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q8N6R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q8WVX3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q8WWP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q96F15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q9H0R3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTGES	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Ptges	IDA		Mouse	PMID:12021206
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Ptges	IDA		Rat	PMID:11067848|RGD:67929
Cellular Component	GO:0016020	membrane	PTGES	IDA		Human	PMID:18682561
Cellular Component	GO:0005641	nuclear envelope lumen	Ptges	IDA		Mouse	PMID:10869354
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ptges	IDA		Rat	PMID:15284079|RGD:2300105
Biological Process	GO:0002526	acute inflammatory response	Ptges	IEP		Rat	PMID:15044444|RGD:2300106
Biological Process	GO:0042074	cell migration involved in gastrulation	ptges	IMP	ZFIN:ZDB-MRPHLNO-060220-2	Zfish	PMID:16391234
Biological Process	GO:0008283	cell population proliferation	Ptges	IGI	MGI:MGI:88039	Mouse	PMID:18485889
Biological Process	GO:0002544	chronic inflammatory response	Ptges	IEP		Rat	PMID:12707354|RGD:2300108
Biological Process	GO:0008285	negative regulation of cell population proliferation	Ptges	IGI	MGI:MGI:88039	Mouse	PMID:18485889
Biological Process	GO:0032308	positive regulation of prostaglandin secretion	Ptges	IMP	MGI:MGI:3051640	Mouse	PMID:26828067
Biological Process	GO:0001516	prostaglandin biosynthetic process	PTGES	IDA		Human	PMID:18682561
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptges	IDA		Mouse	MGI:MGI:6393388|PMID:11795891
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptges	IDA		Rat	PMID:11067848|RGD:67929
Biological Process	GO:0006693	prostaglandin metabolic process	Ptges	IDA		Mouse	PMID:10869354
Biological Process	GO:0031620	regulation of fever generation	Ptges	IMP		Mouse	MGI:MGI:3042060|PMID:14566340
Biological Process	GO:0050727	regulation of inflammatory response	Ptges	IMP		Mouse	MGI:MGI:3045628|PMID:12835414
Biological Process	GO:0051592	response to calcium ion	Ptges	IEP		Rat	PMID:16598755|RGD:2300097
Biological Process	GO:0034097	response to cytokine	Ptges	IEP		Rat	PMID:16816110|RGD:2300095
Biological Process	GO:0032496	response to lipopolysaccharide	Ptges	IEP		Rat	PMID:18383341|RGD:2300090
Biological Process	GO:0014070	response to organic cyclic compound	Ptges	IEP		Rat	PMID:17927823|RGD:2300092
Biological Process	GO:0032526	response to retinoic acid	Ptges	IEP		Rat	PMID:18183617|RGD:2300091
Biological Process	GO:0019233	sensory perception of pain	Ptges	IMP		Mouse	MGI:MGI:3045628|PMID:12835414

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern