Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTGES3
  • Mouse genes Ptges3
  • Rat genes Ptges3
  • Zfish genes ptges3a,ptges3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptges3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070182	DNA polymerase binding	PTGES3	IPI	UniProtKB:O14746	Human	PMID:10197982
Molecular Function	GO:0070182	DNA polymerase binding	PTGES3	IPI	UniProtKB:O14746	Human	PMID:19751963
Molecular Function	GO:0070182	DNA polymerase binding	Ptges3	IPI	UniProtKB:O14746	Mouse	MGI:MGI:5819359|PMID:10197982
Molecular Function	GO:0019899	enzyme binding	Ptges3	IPI	RGD:1303174	Rat	PMID:9488468|RGD:5688104
Molecular Function	GO:0051879	Hsp90 protein binding	PTGES3	IPI	UniProtKB:P08238	Human	PMID:10543959
Molecular Function	GO:0051879	Hsp90 protein binding	PTGES3	IPI	UniProtKB:P08238	Human	PMID:10811660
Molecular Function	GO:0051879	Hsp90 protein binding	PTGES3	IPI	UniProtKB:P07900	Human	PMID:19740745
Molecular Function	GO:0051879	Hsp90 protein binding	Ptges3	IDA		Rat	PMID:12684036|RGD:5688078
Molecular Function	GO:0002039	p53 binding	Ptges3	IDA		Rat	PMID:9488468|RGD:5688104
Molecular Function	GO:0050220	prostaglandin-E synthase activity	PTGES3	IDA		Human	PMID:10922363
Molecular Function	GO:0050220	prostaglandin-E synthase activity	Ptges3	IDA		Rat	PMID:10922363|RGD:5688071
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P07900	Human	PMID:19875381
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P08238	Human	PMID:21183720
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P07900	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P08238	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:Q9UKV8	Human	PMID:23741051
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:O14654	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P07900	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P08238	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P07900	Human	PMID:27353360
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:Q8NFG4	Human	PMID:27353360
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:Q8TF40	Human	PMID:27353360
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:Q9P278	Human	PMID:27353360
Molecular Function	GO:0005515	protein binding	PTGES3	IPI	UniProtKB:P07900	Human	PMID:9817749
Molecular Function	GO:0003720	telomerase activity	PTGES3	IDA		Human	PMID:12135483
Molecular Function	GO:0051082	unfolded protein binding	PTGES3	IDA		Human	PMID:12077419
Cellular Component	GO:0005884	actin filament	Ptges3	IDA		Rat	PMID:8864660|RGD:5688126
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Ptges3	IDA		Rat	PMID:15284079|RGD:2300105
Cellular Component	GO:0043005	neuron projection	Ptges3	IDA		Rat	PMID:20796173|RGD:5508372
Cellular Component	GO:0043025	neuronal cell body	Ptges3	IDA		Rat	PMID:20796173|RGD:5508372
Cellular Component	GO:0005634	nucleus	PTGES3	HDA		Human	PMID:21630459
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ptges3	IDA		Rat	PMID:20796173|RGD:5508372
Cellular Component	GO:0101031	protein folding chaperone complex	PTGES3	IDA		Human	PMID:29127155
Cellular Component	GO:0032991	protein-containing complex	PTGES3	IMP		Human	PMID:10543959
Cellular Component	GO:0032991	protein-containing complex	PTGES3	IMP		Human	PMID:10811660
Cellular Component	GO:0032991	protein-containing complex	Ptges3	IDA		Rat	PMID:20796173|RGD:5508372
Cellular Component	GO:0005697	telomerase holoenzyme complex	PTGES3	IDA		Human	PMID:12135483
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	PTGES3	IDA		Human	PMID:12853476
Biological Process	GO:0051131	chaperone-mediated protein complex assembly	PTGES3	IMP		Human	PMID:10811660
Biological Process	GO:0048144	fibroblast proliferation	Ptges3	IMP	MGI:MGI:3701300	Mouse	PMID:17438133
Biological Process	GO:0042921	glucocorticoid receptor signaling pathway	Ptges3	IMP	MGI:MGI:3701300	Mouse	PMID:17438133
Biological Process	GO:0005978	glycogen biosynthetic process	Ptges3	IMP	MGI:MGI:3701300	Mouse	PMID:17438133
Biological Process	GO:0060430	lung saccule development	Ptges3	IMP	MGI:MGI:3701300	Mouse	PMID:17438133
Biological Process	GO:0051402	neuron apoptotic process	Ptges3	IMP		Rat	PMID:19145491|RGD:5688073
Biological Process	GO:0010628	positive regulation of gene expression	Ptges3	IMP		Rat	PMID:21334450|RGD:5688070
Biological Process	GO:0042327	positive regulation of phosphorylation	PTGES3	IDA		Human	PMID:19740745
Biological Process	GO:0051973	positive regulation of telomerase activity	PTGES3	IDA		Human	PMID:10197982
Biological Process	GO:0051973	positive regulation of telomerase activity	PTGES3	IDA		Human	PMID:19740745
Biological Process	GO:0051973	positive regulation of telomerase activity	PTGES3	IMP		Human	PMID:19740745
Biological Process	GO:0051973	positive regulation of telomerase activity	Ptges3	IDA		Mouse	MGI:MGI:5819359|PMID:10197982
Biological Process	GO:0001516	prostaglandin biosynthetic process	PTGES3	IDA		Human	PMID:10922363
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptges3	IMP	MGI:MGI:3701300	Mouse	PMID:17438133
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptges3	IDA		Rat	PMID:10922363|RGD:5688071
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptges3	IMP		Rat	PMID:10922363|RGD:5688071
Biological Process	GO:0006693	prostaglandin metabolic process	Ptges3	IMP		Rat	PMID:21334450|RGD:5688070
Biological Process	GO:0050821	protein stabilization	PTGES3	IMP		Human	PMID:10543959
Biological Process	GO:0050821	protein stabilization	PTGES3	IMP		Human	PMID:10811660
Biological Process	GO:0019233	sensory perception of pain	Ptges3	IMP		Rat	PMID:16192391|RGD:5688057
Biological Process	GO:0043588	skin development	Ptges3	IMP	MGI:MGI:3701300	Mouse	PMID:17438133
Biological Process	GO:1905323	telomerase holoenzyme complex assembly	PTGES3	IDA		Human	PMID:10197982
Biological Process	GO:1905323	telomerase holoenzyme complex assembly	Ptges3	IDA		Mouse	MGI:MGI:5819359|PMID:10197982
Biological Process	GO:0007004	telomere maintenance via telomerase	PTGES3	IDA		Human	PMID:10197982
Biological Process	GO:0007004	telomere maintenance via telomerase	PTGES3	IDA		Human	PMID:19740745
Biological Process	GO:0007004	telomere maintenance via telomerase	PTGES3	IMP		Human	PMID:19740745
Biological Process	GO:0007004	telomere maintenance via telomerase	Ptges3	IDA		Mouse	MGI:MGI:5819359|PMID:10197982

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern