Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTGIR
  • Mouse genes Ptgir
  • Rat genes Ptgir
  • Zfish genes ptgir
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptgir

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016501	prostacyclin receptor activity	ptgir	IDA		Zfish	PMID:23770421
Cellular Component	GO:0005829	cytosol	PTGIR	IDA		Human	PMID:20622039
Cellular Component	GO:0005886	plasma membrane	PTGIR	IDA		Human	PMID:20622039
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	PTGIR	IMP		Human	PMID:20622039
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ptgir	IMP		Mouse	MGI:MGI:5437428|PMID:20622039
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ptgir	IDA		Zfish	PMID:23770421|ZFIN:ZDB-PUB-130710-8
Biological Process	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	Ptgir	IMP		Mouse	MGI:MGI:5437428|PMID:20622039
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	PTGIR	IDA		Human	PMID:20622039
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	Ptgir	IMP		Mouse	MGI:MGI:5437428|PMID:20622039
Biological Process	GO:0032496	response to lipopolysaccharide	Ptgir	IMP	MGI:MGI:2137832	Mouse	PMID:15834430

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern