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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pth1r

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pth1r
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0004991parathyroid hormone receptor activityPTH1RIDAHumanPMID:19674967
Molecular FunctionGO:0004991parathyroid hormone receptor activityPTH1RIDAHumanPMID:8397094
Molecular FunctionGO:0004991parathyroid hormone receptor activityPth1rIMPMGI:MGI:2154519MousePMID:9832460
Molecular FunctionGO:0004991parathyroid hormone receptor activityPth1rIDARatPMID:1313566|RGD:727526
Molecular FunctionGO:0004991parathyroid hormone receptor activityPth1rIDARatPMID:19608645|RGD:8553376
Molecular FunctionGO:0004991parathyroid hormone receptor activityPth1rIDARatPMID:9054374|RGD:7207455
Molecular FunctionGO:0004991parathyroid hormone receptor activityPth1rIDARatPMID:9642250|RGD:7207454
Molecular FunctionGO:0004991parathyroid hormone receptor activitypth1rIDAZfishPMID:10965877
Molecular FunctionGO:0004991parathyroid hormone receptor activitypth1rIDAZfishPMID:10497171
Molecular FunctionGO:0017046peptide hormone bindingPTH1RIDAHumanPMID:19674967
Molecular FunctionGO:0017046peptide hormone bindingPth1rIDARatPMID:19608645|RGD:8553376
Molecular FunctionGO:0017046peptide hormone bindingPth1rIDARatPMID:9054374|RGD:7207455
Molecular FunctionGO:0017046peptide hormone bindingPth1rIDARatPMID:9642250|RGD:7207454
Molecular FunctionGO:0017046peptide hormone bindingpth1rIDAZfishPMID:10497171
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:P01270HumanPMID:19674967
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:P12272HumanPMID:19674967
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:P35222HumanPMID:23124878
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:O75716HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:O95872HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:P49639HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:Q13064HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:Q8WW24HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:Q92922HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingPTH1RIPIUniProtKB:Q96NT3-2HumanPMID:32296183
Molecular FunctionGO:0042803protein homodimerization activityPTH1RIDAHumanPMID:27160269
Molecular FunctionGO:0043621protein self-associationPTH1RIDAHumanPMID:19674967
Cellular ComponentGO:0016324apical plasma membranePth1rIDARatPMID:19608645|RGD:8553376
Cellular ComponentGO:0016323basolateral plasma membranePth1rIDARatPMID:12647298|RGD:1599981
Cellular ComponentGO:0016323basolateral plasma membranePth1rIDARatPMID:19608645|RGD:8553376
Cellular ComponentGO:0031526brush border membranePth1rIDARatPMID:12647298|RGD:1599981
Cellular ComponentGO:0005737cytoplasmPth1rIDARatPMID:12647298|RGD:1599981
Cellular ComponentGO:0005622intracellular anatomical structurePth1rIDAMousePMID:8895385
Cellular ComponentGO:0005634nucleusPth1rIDARatPMID:12647298|RGD:1599981
Cellular ComponentGO:0005886plasma membranePTH1RIDAHumanPMID:19674967
Cellular ComponentGO:0005886plasma membranePTH1RIMPHumanPMID:8397094
Cellular ComponentGO:0005886plasma membranePth1rIDARatPMID:8662729|RGD:7207456
Cellular ComponentGO:0043235receptor complexPth1rIDARatPMID:19608645|RGD:8553376
Biological ProcessGO:0007189adenylate cyclase-activating G protein-coupled receptor signaling pathwayPTH1RIDAHumanPMID:27160269
Biological ProcessGO:0007189adenylate cyclase-activating G protein-coupled receptor signaling pathwayPTH1RIDAHumanPMID:8397094
Biological ProcessGO:0007189adenylate cyclase-activating G protein-coupled receptor signaling pathwayPth1rIMPMGI:MGI:2154519MousePMID:9832460
Biological ProcessGO:0007189adenylate cyclase-activating G protein-coupled receptor signaling pathwayPth1rIDARatPMID:19608645|RGD:8553376
Biological ProcessGO:0007188adenylate cyclase-modulating G protein-coupled receptor signaling pathwayPTH1RIDAHumanPMID:19674967
Biological ProcessGO:0007188adenylate cyclase-modulating G protein-coupled receptor signaling pathwayPth1rIDARatPMID:19608645|RGD:8553376
Biological ProcessGO:0007568agingPth1rIEPRatPMID:12647298|RGD:1599981
Biological ProcessGO:0030282bone mineralizationPth1rIMPMGI:MGI:2154519MousePMID:11606467
Biological ProcessGO:0030282bone mineralizationPth1rIMPMGI:MGI:2154519MousePMID:9832460
Biological ProcessGO:0045453bone resorptionPth1rIMPMGI:MGI:2154519MousePMID:9832460
Biological ProcessGO:0048469cell maturationPth1rIMPMGI:MGI:3628795MousePMID:12194850
Biological ProcessGO:0008283cell population proliferationPth1rIGIMGI:MGI:99829MousePMID:16476422
Biological ProcessGO:0008283cell population proliferationPth1rIMPMGI:MGI:3628795MousePMID:12194850
Biological ProcessGO:0002062chondrocyte differentiationPth1rIGIMGI:MGI:99829MousePMID:16476422
Biological ProcessGO:0002062chondrocyte differentiationPth1rIMPMGI:MGI:2154519MousePMID:9832460
Biological ProcessGO:0035907dorsal aorta developmentpth1rIMPZFIN:ZDB-MRPHLNO-150625-4ZfishPMID:23559631
Biological ProcessGO:0007187G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerPth1rIMPRatPMID:8662729|RGD:7207456
Biological ProcessGO:0001701in utero embryonic developmentPth1rIMPMGI:MGI:5014612MousePMID:27996060
Biological ProcessGO:0006874intracellular calcium ion homeostasisPth1rIMPMGI:MGI:2154519MousePMID:9832460
Biological ProcessGO:0008285negative regulation of cell population proliferationPth1rIMPMGI:MGI:3628795MousePMID:12194850
Biological ProcessGO:0001503ossificationPth1rIMPMGI:MGI:3628795MousePMID:12194850
Biological ProcessGO:0002076osteoblast developmentPth1rIMPMGI:MGI:2154519MousePMID:9832460
Biological ProcessGO:0007200phospholipase C-activating G protein-coupled receptor signaling pathwayPth1rIMPMGI:MGI:3628795MousePMID:12194850
Biological ProcessGO:0007200phospholipase C-activating G protein-coupled receptor signaling pathwayPth1rIDARatPMID:9054374|RGD:7207455
Biological ProcessGO:0008284positive regulation of cell population proliferationPth1rIGIMGI:MGI:99829MousePMID:16476422
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationPth1rIDARatPMID:1313566|RGD:727526
Biological ProcessGO:0060732positive regulation of inositol phosphate biosynthetic processPth1rIDARatPMID:19608645|RGD:8553376
Biological ProcessGO:0060732positive regulation of inositol phosphate biosynthetic processpth1rIDAZfishPMID:10497171
Biological ProcessGO:0001501skeletal system developmentPth1rIMPMGI:MGI:2154519MousePMID:11606467
Biological ProcessGO:0001501skeletal system developmentPth1rIMPMGI:MGI:2154519MousePMID:8662561

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory