Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pth1r

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PTH1R
- Mouse genes Pth1r
- Rat genes Pth1r
- Zfish genes pth1r
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pth1r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004991	parathyroid hormone receptor activity	PTH1R	IDA		Human	PMID:19674967
Molecular Function	GO:0004991	parathyroid hormone receptor activity	PTH1R	IDA		Human	PMID:8397094
Molecular Function	GO:0004991	parathyroid hormone receptor activity	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:9832460
Molecular Function	GO:0004991	parathyroid hormone receptor activity	Pth1r	IDA		Rat	PMID:1313566\|RGD:727526
Molecular Function	GO:0004991	parathyroid hormone receptor activity	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Molecular Function	GO:0004991	parathyroid hormone receptor activity	Pth1r	IDA		Rat	PMID:9054374\|RGD:7207455
Molecular Function	GO:0004991	parathyroid hormone receptor activity	Pth1r	IDA		Rat	PMID:9642250\|RGD:7207454
Molecular Function	GO:0004991	parathyroid hormone receptor activity	pth1r	IDA		Zfish	PMID:10965877
Molecular Function	GO:0004991	parathyroid hormone receptor activity	pth1r	IDA		Zfish	PMID:10497171
Molecular Function	GO:0017046	peptide hormone binding	PTH1R	IDA		Human	PMID:19674967
Molecular Function	GO:0017046	peptide hormone binding	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Molecular Function	GO:0017046	peptide hormone binding	Pth1r	IDA		Rat	PMID:9054374\|RGD:7207455
Molecular Function	GO:0017046	peptide hormone binding	Pth1r	IDA		Rat	PMID:9642250\|RGD:7207454
Molecular Function	GO:0017046	peptide hormone binding	pth1r	IDA		Zfish	PMID:10497171
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:P01270	Human	PMID:19674967
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:P12272	Human	PMID:19674967
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:P35222	Human	PMID:23124878
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:O95872	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:Q8WW24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:Q92922	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTH1R	IPI	UniProtKB:Q96NT3-2	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	PTH1R	IDA		Human	PMID:27160269
Molecular Function	GO:0043621	protein self-association	PTH1R	IDA		Human	PMID:19674967
Cellular Component	GO:0016324	apical plasma membrane	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Cellular Component	GO:0016323	basolateral plasma membrane	Pth1r	IDA		Rat	PMID:12647298\|RGD:1599981
Cellular Component	GO:0016323	basolateral plasma membrane	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Cellular Component	GO:0031526	brush border membrane	Pth1r	IDA		Rat	PMID:12647298\|RGD:1599981
Cellular Component	GO:0005737	cytoplasm	Pth1r	IDA		Rat	PMID:12647298\|RGD:1599981
Cellular Component	GO:0005622	intracellular anatomical structure	Pth1r	IDA		Mouse	PMID:8895385
Cellular Component	GO:0005634	nucleus	Pth1r	IDA		Rat	PMID:12647298\|RGD:1599981
Cellular Component	GO:0005886	plasma membrane	PTH1R	IDA		Human	PMID:19674967
Cellular Component	GO:0005886	plasma membrane	PTH1R	IMP		Human	PMID:8397094
Cellular Component	GO:0005886	plasma membrane	Pth1r	IDA		Rat	PMID:8662729\|RGD:7207456
Cellular Component	GO:0043235	receptor complex	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	PTH1R	IDA		Human	PMID:27160269
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	PTH1R	IDA		Human	PMID:8397094
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:9832460
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	PTH1R	IDA		Human	PMID:19674967
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Biological Process	GO:0007568	aging	Pth1r	IEP		Rat	PMID:12647298\|RGD:1599981
Biological Process	GO:0030282	bone mineralization	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:11606467
Biological Process	GO:0030282	bone mineralization	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:9832460
Biological Process	GO:0045453	bone resorption	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:9832460
Biological Process	GO:0048469	cell maturation	Pth1r	IMP	MGI:MGI:3628795	Mouse	PMID:12194850
Biological Process	GO:0008283	cell population proliferation	Pth1r	IGI	MGI:MGI:99829	Mouse	PMID:16476422
Biological Process	GO:0008283	cell population proliferation	Pth1r	IMP	MGI:MGI:3628795	Mouse	PMID:12194850
Biological Process	GO:0002062	chondrocyte differentiation	Pth1r	IGI	MGI:MGI:99829	Mouse	PMID:16476422
Biological Process	GO:0002062	chondrocyte differentiation	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:9832460
Biological Process	GO:0035907	dorsal aorta development	pth1r	IMP	ZFIN:ZDB-MRPHLNO-150625-4	Zfish	PMID:23559631
Biological Process	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Pth1r	IMP		Rat	PMID:8662729\|RGD:7207456
Biological Process	GO:0001701	in utero embryonic development	Pth1r	IMP	MGI:MGI:5014612	Mouse	PMID:27996060
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:9832460
Biological Process	GO:0008285	negative regulation of cell population proliferation	Pth1r	IMP	MGI:MGI:3628795	Mouse	PMID:12194850
Biological Process	GO:0001503	ossification	Pth1r	IMP	MGI:MGI:3628795	Mouse	PMID:12194850
Biological Process	GO:0002076	osteoblast development	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:9832460
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Pth1r	IMP	MGI:MGI:3628795	Mouse	PMID:12194850
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Pth1r	IDA		Rat	PMID:9054374\|RGD:7207455
Biological Process	GO:0008284	positive regulation of cell population proliferation	Pth1r	IGI	MGI:MGI:99829	Mouse	PMID:16476422
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Pth1r	IDA		Rat	PMID:1313566\|RGD:727526
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	Pth1r	IDA		Rat	PMID:19608645\|RGD:8553376
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	pth1r	IDA		Zfish	PMID:10497171
Biological Process	GO:0001501	skeletal system development	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:11606467
Biological Process	GO:0001501	skeletal system development	Pth1r	IMP	MGI:MGI:2154519	Mouse	PMID:8662561

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/03/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.