Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTK6
  • Mouse genes Ptk6
  • Rat genes Ptk6
  • Zfish genes ptk6a,ptk6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptk6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	PTK6	IPI	UniProtKB:Q13882	Human	PMID:15056653
Molecular Function	GO:0042802	identical protein binding	PTK6	IPI	UniProtKB:Q13882	Human	PMID:18719096
Molecular Function	GO:0042802	identical protein binding	PTK6	IPI	UniProtKB:Q13882	Human	PMID:19401189
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	PTK6	IDA		Human	PMID:10913193
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q07666	Human	PMID:10913193
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q06187	Human	PMID:15539407
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P49023	Human	PMID:15572663
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P40763	Human	PMID:16568091
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P04626	Human	PMID:18719096
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P23246	Human	PMID:19439179
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P04626	Human	PMID:20700126
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q13480	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:O00401	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:O00471	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:O14526	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q5JST6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q5VWX1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:O14526	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q5JST6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q5VWX1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P08238	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q16543	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q92841	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:O00471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:O14770-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P78337	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q08043	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q13191	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q13239-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q3KP44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q5T5P2-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q8N9I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q8TDC0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q92841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q9BYN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q9NQX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:Q9UKT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTK6	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:16568091
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:18719096
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:18829532
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:19393627
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:20554524
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:20606012
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:22084245
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:25733683
Molecular Function	GO:0004713	protein tyrosine kinase activity	PTK6	EXP		Human	PMID:26751287
Cellular Component	GO:0005737	cytoplasm	PTK6	IDA		Human	PMID:15572663
Cellular Component	GO:0005829	cytosol	PTK6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	PTK6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PTK6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PTK6	IDA		Human	PMID:10913193
Cellular Component	GO:0005634	nucleus	Ptk6	IDA		Mouse	PMID:12200423
Cellular Component	GO:0005634	nucleus	Ptk6	IDA		Mouse	PMID:12833144
Cellular Component	GO:0005886	plasma membrane	PTK6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001726	ruffle	PTK6	IDA		Human	PMID:15572663
Biological Process	GO:0016477	cell migration	PTK6	IDA		Human	PMID:15572663
Biological Process	GO:0071300	cellular response to retinoic acid	PTK6	IMP		Human	PMID:17910947
Biological Process	GO:0060575	intestinal epithelial cell differentiation	Ptk6	IMP		Mouse	MGI:MGI:3640030|PMID:16782882
Biological Process	GO:0045926	negative regulation of growth	Ptk6	IMP		Mouse	MGI:MGI:3640030|PMID:16782882
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	PTK6	IDA		Human	PMID:15539407
Biological Process	GO:0010976	positive regulation of neuron projection development	PTK6	IMP		Human	PMID:17910947
Biological Process	GO:0046777	protein autophosphorylation	PTK6	IMP		Human	PMID:12121988
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	PTK6	IDA		Human	PMID:16568091
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	PTK6	IDA		Human	PMID:17997837

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern