Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTP4A3
  • Mouse genes Ptp4a3
  • Rat genes Ptp4a3
  • Zfish genes ptp4a3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptp4a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PTP4A3	IPI	UniProtKB:Q9NYB0	Human	PMID:23178297
Cellular Component	GO:0005737	cytoplasm	PTP4A3	IMP		Human	PMID:23178297
Cellular Component	GO:0005634	nucleus	PTP4A3	IMP		Human	PMID:23178297
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Ptp4a3	IEP		Mouse	PMID:20439489
Biological Process	GO:0043542	endothelial cell migration	PTP4A3	IMP		Human	PMID:24403062
Biological Process	GO:0043542	endothelial cell migration	Ptp4a3	IMP	MGI:MGI:5461469	Mouse	PMID:24403062
Biological Process	GO:0007219	Notch signaling pathway	Ptp4a3	IDA		Mouse	PMID:23117660
Biological Process	GO:1904951	positive regulation of establishment of protein localization	PTP4A3	IMP		Human	PMID:23178297
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	PTP4A3	IDA		Human	PMID:23178297
Biological Process	GO:0043117	positive regulation of vascular permeability	Ptp4a3	IMP	MGI:MGI:5461469	Mouse	PMID:24403062
Biological Process	GO:0006355	regulation of DNA-templated transcription	PTP4A3	IDA		Human	PMID:23178297
Biological Process	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	Ptp4a3	IMP	MGI:MGI:5461469	Mouse	PMID:24403062

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern