Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPN11
  • Mouse genes Ptpn11
  • Rat genes Ptpn11
  • Zfish genes ptpn11a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpn11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	PTPN11	IPI	UniProtKB:P33151	Human	PMID:15985432
Molecular Function	GO:0050839	cell adhesion molecule binding	PTPN11	IPI	UniProtKB:P16284	Human	PMID:15985432
Molecular Function	GO:0050839	cell adhesion molecule binding	Ptpn11	IPI	UniProtKB:P16573	Mouse	MGI:MGI:5770065|PMID:19948503
Molecular Function	GO:0050839	cell adhesion molecule binding	Ptpn11	IPI	RGD:61927	Rat	PMID:9388260|RGD:2311659
Molecular Function	GO:0031748	D1 dopamine receptor binding	Ptpn11	IPI	RGD:2518	Rat	PMID:23328768|RGD:7248590
Molecular Function	GO:0005158	insulin receptor binding	PTPN11	IPI	UniProtKB:P06213-2	Human	PMID:7493946
Molecular Function	GO:0005158	insulin receptor binding	Ptpn11	IDA		Rat	PMID:7711057|RGD:2293185
Molecular Function	GO:0043560	insulin receptor substrate binding	Ptpn11	IPI	RGD:69316	Rat	PMID:12891559|RGD:1299201
Molecular Function	GO:0060090	molecular adaptor activity	PTPN11	IDA		Human	PMID:26358190
Molecular Function	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	PTPN11	IMP		Human	PMID:10655584
Molecular Function	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	PTPN11	IDA		Human	PMID:16481357
Molecular Function	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	Ptpn11	IMP	MGI:MGI:3050284	Mouse	PMID:15273746
Molecular Function	GO:0051428	peptide hormone receptor binding	Ptpn11	IPI	PR:P48356	Mouse	PMID:15520383
Molecular Function	GO:0016791	phosphatase activity	ptpn11a	IDA		Zfish	PMID:24736444
Molecular Function	GO:0043274	phospholipase binding	Ptpn11	IDA		Rat	PMID:16814162|RGD:1601575
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	PTPN11	IDA		Human	PMID:15133037
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Ptpn11	IMP	MGI:MGI:3050284	Mouse	PMID:15273746
Molecular Function	GO:0001784	phosphotyrosine residue binding	PTPN11	IPI	UniProtKB:Q96RL6	Human	PMID:11986327
Molecular Function	GO:0001784	phosphotyrosine residue binding	PTPN11	IMP		Human	PMID:12051764
Molecular Function	GO:0001784	phosphotyrosine residue binding	PTPN11	IPI	UniProtKB:Q96P31	Human	PMID:12051764
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P20138	Human	PMID:10206955
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9UGN4	Human	PMID:10540326
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P29317	Human	PMID:10655584
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P35570	Human	PMID:10660596
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:O95297	Human	PMID:10681522
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P16284	Human	PMID:10704309
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P20138	Human	PMID:10887109
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:11323411
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:11453982
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:12577067
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P09619	Human	PMID:12614164
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:12855672
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P49023	Human	PMID:14665621
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:14665621
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:14701753
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q14764	Human	PMID:15133037
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9UQC2	Human	PMID:15170389
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q15116	Human	PMID:15240681
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:15574420
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:15985432
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9UQC2	Human	PMID:16253990
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9UGN4	Human	PMID:16254138
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q08345	Human	PMID:16337946
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9UGN4	Human	PMID:16339535
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P32239	Human	PMID:16963136
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q2HXU8	Human	PMID:17562706
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P68105	Human	PMID:17936057
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q71V39	Human	PMID:17936057
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P20138	Human	PMID:17947393
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P08581	Human	PMID:18579758
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P43626	Human	PMID:18604210
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9UQC2	Human	PMID:19172738
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q14511	Human	PMID:19275884
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9H706	Human	PMID:19509291
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q96P31	Human	PMID:19843936
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:20308328
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P00533	Human	PMID:20473329
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:20473329
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:20473329
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q6DN72	Human	PMID:20933011
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P49247	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:O95866	Human	PMID:23112346
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P09619	Human	PMID:23397142
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P49023	Human	PMID:23397142
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q9BZW8	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P08581	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P10275	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P49247	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13049	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q6P1J9	Human	PMID:26742426
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q6DKI7	Human	PMID:26755705
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13049	Human	PMID:27229929
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q15116	Human	PMID:28046066
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P00533	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P04626	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P08069	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P29317	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q8WU20	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13049	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:31585087
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q2HXU8	Human	PMID:34310951
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P00533	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P06213	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P08069	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P29317	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q8WU20	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P06213	Human	PMID:7493946
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P35570	Human	PMID:7504175
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P35568	Human	PMID:7513703
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P62993	Human	PMID:7523381
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P09619	Human	PMID:7530043
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P08069	Human	PMID:7642582
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P09619	Human	PMID:7688466
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P09619	Human	PMID:8119896
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P09619	Human	PMID:8183548
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P09619	Human	PMID:8538796
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P43628	Human	PMID:8648092
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P97710	Human	PMID:8810330
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P08069	Human	PMID:8895367
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P16284	Human	PMID:9312087
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P97710	Human	PMID:9535915
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P06213	Human	PMID:9593725
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q8WU20	Human	PMID:9632781
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:Q13480	Human	PMID:9658397
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:P16284	Human	PMID:9774457
Molecular Function	GO:0005515	protein binding	PTPN11	IPI	UniProtKB:O95297	Human	PMID:9792637
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P97797	Mouse	MGI:MGI:3760575|PMID:17954568
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q3TB92	Mouse	MGI:MGI:4461821|PMID:20526344
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P62993	Mouse	MGI:MGI:5520050|PMID:11432792
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P16879|UniProtKB:P70196	Mouse	MGI:MGI:5432331|PMID:22522491
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q60631	Mouse	MGI:MGI:5553227|PMID:23452850
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P62993	Mouse	MGI:MGI:5508314|PMID:8959326
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:D7PDD4	Mouse	MGI:MGI:5512895|PMID:23112346
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P97484	Mouse	MGI:MGI:5432830|PMID:22660330
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P28776	Mouse	MGI:MGI:5291886|PMID:21804557
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P10721|UniProtKB:P62993	Mouse	MGI:MGI:4441156|PMID:7523381
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P30999	Mouse	MGI:MGI:5508305|PMID:9670943
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P15209|UniProtKB:Q8K4V6	Mouse	MGI:MGI:4949042|PMID:21364532
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P97484	Mouse	MGI:MGI:5511064|PMID:24052308
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P62993	Mouse	MGI:MGI:5508321|PMID:7522233
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P62993|UniProtKB:Q60631	Mouse	MGI:MGI:5508291|PMID:11684012
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q64281	Mouse	MGI:MGI:6827314|PMID:10026201
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q91VW7	Mouse	PMID:12808090
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q91VW7	Mouse	PMID:15273746
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:A1YIY0	Mouse	PMID:17213291
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:P31809-1	Mouse	PMID:9867848
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:Q7TSP5	Mouse	PMID:15568026
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:Q3TEW6-1	Mouse	PMID:17440960
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:Q8BSM5	Mouse	PMID:11739737
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q9R1X3	Mouse	PMID:11895767
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:Q7TSA3	Mouse	PMID:15568026
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:Q7TSA3	Mouse	PMID:12796776
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	PR:Q6SJQ0	Mouse	PMID:12893283
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	RGD:621367	Rat	PMID:12959980|RGD:12743580
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q86YW5-1	Rat	PMID:15128762|RGD:8554352
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P09619	Rat	PMID:31585087|RGD:21201274
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P09619	Rat	PMID:7545675|RGD:21201264
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:P97710	Rat	PMID:8810330|RGD:729736
Molecular Function	GO:0005515	protein binding	Ptpn11	IPI	UniProtKB:Q62689	Rat	PMID:8912646|RGD:8553635
Molecular Function	GO:0005515	protein binding	ptpn11a	IPI	ZFIN:ZDB-GENE-050417-455	Zfish	PMID:24865967
Molecular Function	GO:0019904	protein domain specific binding	Ptpn11	IPI	RGD:619758	Rat	PMID:10973965|RGD:2303503
Molecular Function	GO:0019904	protein domain specific binding	Ptpn11	IPI	RGD:621367	Rat	PMID:10973965|RGD:2303503
Molecular Function	GO:0019901	protein kinase binding	Ptpn11	IPI	UniProtKB:O88351|UniProtKB:Q9WUN2	Mouse	MGI:MGI:3760575|PMID:17954568
Molecular Function	GO:1990782	protein tyrosine kinase binding	PTPN11	IPI	UniProtKB:P35968	Human	PMID:15985432
Molecular Function	GO:1990782	protein tyrosine kinase binding	PTPN11	IPI	UniProtKB:Q02763	Human	PMID:15985432
Molecular Function	GO:1990782	protein tyrosine kinase binding	Ptpn11	IPI	RGD:735296	Rat	PMID:16690621|RGD:1601574
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	IMP		Human	PMID:10206955
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	IDA		Human	PMID:15133037
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	IMP		Human	PMID:17562706
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	EXP		Human	PMID:22759635
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	IDA		Human	PMID:23029125
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	EXP		Human	PMID:26617336
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	IDA		Human	PMID:26742426
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN11	IDA		Human	PMID:28074573
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn11	IDA		Mouse	PMID:18827006
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn11	IDA		Rat	PMID:15272025|RGD:1581313
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn11	IDA		Rat	PMID:15378208|RGD:1601573
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn11	IDA		Rat	PMID:7512964|RGD:729786
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn11	IDA		Rat	PMID:7711057|RGD:2293185
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ptpn11a	IDA		Zfish	PMID:18159945
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Ptpn11	IPI	UniProtKB:P08922	Mouse	MGI:MGI:3655533|PMID:16885344
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Ptpn11	IPI	RGD:3556	Rat	PMID:15115663|RGD:1601572
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	PTPN11	IPI	UniProtKB:P06213,UniProtKB:P35568	Human	PMID:7493946
Cellular Component	GO:0005737	cytoplasm	PTPN11	IDA		Human	PMID:10940933
Cellular Component	GO:0005737	cytoplasm	PTPN11	IDA		Human	PMID:15133037
Cellular Component	GO:0005737	cytoplasm	PTPN11	IDA		Human	PMID:26742426
Cellular Component	GO:0005737	cytoplasm	Ptpn11	IDA		Rat	PMID:19348936|RGD:39131290
Cellular Component	GO:0005829	cytosol	Ptpn11	IDA		Rat	PMID:7711057|RGD:2293185
Cellular Component	GO:0005739	mitochondrion	Ptpn11	IDA		Rat	PMID:15378208|RGD:1601573
Cellular Component	GO:0005634	nucleus	PTPN11	IDA		Human	PMID:15133037
Cellular Component	GO:0005634	nucleus	PTPN11	IDA		Human	PMID:26742426
Cellular Component	GO:0005886	plasma membrane	Ptpn11	IDA		Rat	PMID:19348936|RGD:39131290
Cellular Component	GO:0044853	plasma membrane raft	Ptpn11	IDA		Rat	PMID:19348936|RGD:39131290
Cellular Component	GO:0032991	protein-containing complex	PTPN11	IMP		Human	PMID:17562706
Cellular Component	GO:0032991	protein-containing complex	Ptpn11	IDA		Rat	PMID:10973965|RGD:2303503
Biological Process	GO:0036302	atrioventricular canal development	PTPN11	IMP		Human	PMID:12058348
Biological Process	GO:0007409	axonogenesis	Ptpn11	IMP		Mouse	PMID:12482708
Biological Process	GO:0060020	Bergmann glial cell differentiation	Ptpn11	IGI	MGI:MGI:1346866	Mouse	PMID:24431450
Biological Process	GO:0060020	Bergmann glial cell differentiation	Ptpn11	IMP	MGI:MGI:4868451	Mouse	PMID:24431450
Biological Process	GO:0007420	brain development	PTPN11	IMP		Human	PMID:11704759
Biological Process	GO:0008283	cell population proliferation	ptpn11a	IGI	ZFIN:ZDB-GENE-030131-5911	Zfish	PMID:29203641
Biological Process	GO:0008283	cell population proliferation	ptpn11a	IMP	ZFIN:ZDB-GENO-180724-3	Zfish	PMID:29203641
Biological Process	GO:0008283	cell population proliferation	ptpn11a	IMP		Zfish	PMID:29203641
Biological Process	GO:0008283	cell population proliferation	ptpn11a	IGI	ZFIN:ZDB-GENE-040426-1158	Zfish	PMID:29203641
Biological Process	GO:1904385	cellular response to angiotensin	Ptpn11	IEP		Rat	PMID:9139682|RGD:39456085
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	PTPN11	IMP		Human	PMID:28074573
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ptpn11	IEP		Rat	PMID:19348936|RGD:39131290
Biological Process	GO:1990314	cellular response to insulin-like growth factor stimulus	Ptpn11	IEP		Rat	PMID:9139682|RGD:39456085
Biological Process	GO:0071260	cellular response to mechanical stimulus	Ptpn11	IPI	RGD:3443	Rat	PMID:18757826|RGD:12743581
Biological Process	GO:0021697	cerebellar cortex formation	Ptpn11	IGI	MGI:MGI:1346866	Mouse	PMID:24431450
Biological Process	GO:0021697	cerebellar cortex formation	Ptpn11	IMP	MGI:MGI:4868451	Mouse	PMID:24431450
Biological Process	GO:0060028	convergent extension involved in axis elongation	ptpn11a	IMP	ZFIN:ZDB-MRPHLNO-070904-9	Zfish	PMID:24865967
Biological Process	GO:0060027	convergent extension involved in gastrulation	ptpn11a	IMP	ZFIN:ZDB-MRPHLNO-080801-1	Zfish	PMID:18159945
Biological Process	GO:0060027	convergent extension involved in gastrulation	ptpn11a	IGI	ZFIN:ZDB-MRPHLNO-041217-11,ZFIN:ZDB-MRPHLNO-080801-1	Zfish	PMID:18159945
Biological Process	GO:0000077	DNA damage checkpoint signaling	Ptpn11	IMP	MGI:MGI:2176524	Mouse	PMID:12937170
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	ptpn11a	IGI	ZFIN:ZDB-GENO-140805-4	Zfish	PMID:24736444
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	ptpn11a	IMP	ZFIN:ZDB-GENO-140805-2	Zfish	PMID:24736444
Biological Process	GO:0048013	ephrin receptor signaling pathway	PTPN11	IDA		Human	PMID:10655584
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Ptpn11	IGI	MGI:MGI:95294	Mouse	PMID:10700187
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Ptpn11	IGI	MGI:MGI:87859	Mouse	PMID:18827006
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Ptpn11	IGI	MGI:MGI:95294	Mouse	PMID:18827006
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Ptpn11	IGI	MGI:MGI:87860	Mouse	PMID:18827006
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Ptpn11	IGI	MGI:MGI:95290	Mouse	PMID:18827006
Biological Process	GO:0038127	ERBB signaling pathway	PTPN11	IDA		Human	PMID:15133037
Biological Process	GO:0060325	face morphogenesis	PTPN11	IMP		Human	PMID:11704759
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	PTPN11	IMP	FB:FBgn0014135|FB:FBgn0014388	Human	PMID:16481357
Biological Process	GO:0048806	genitalia development	PTPN11	IMP		Human	PMID:12058348
Biological Process	GO:0042593	glucose homeostasis	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0007507	heart development	PTPN11	IMP		Human	PMID:12058348
Biological Process	GO:0007507	heart development	ptpn11a	IMP	ZFIN:ZDB-MRPHLNO-070904-9	Zfish	PMID:17603482
Biological Process	GO:0003146	heart jogging	ptpn11a	IMP	ZFIN:ZDB-MRPHLNO-080801-1	Zfish	PMID:18159945
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Ptpn11	IGI	MGI:MGI:96680	Mouse	PMID:24675817
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Ptpn11	IMP	MGI:MGI:3690333	Mouse	PMID:24675817
Biological Process	GO:0042445	hormone metabolic process	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0009755	hormone-mediated signaling pathway	Ptpn11	IDA		Mouse	PMID:15520383
Biological Process	GO:0048839	inner ear development	PTPN11	IMP		Human	PMID:12058348
Biological Process	GO:0007229	integrin-mediated signaling pathway	Ptpn11	IMP	MGI:MGI:3690333	Mouse	PMID:23509158
Biological Process	GO:0061582	intestinal epithelial cell migration	Ptpn11	IMP	MGI:MGI:3690333	Mouse	PMID:24675817
Biological Process	GO:0006629	lipid metabolic process	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0000165	MAPK cascade	ptpn11a	IMP	ZFIN:ZDB-GENO-180724-3	Zfish	PMID:29203641
Biological Process	GO:0000165	MAPK cascade	ptpn11a	IGI	ZFIN:ZDB-GENE-040426-1158	Zfish	PMID:29203641
Biological Process	GO:0035855	megakaryocyte development	Ptpn11	IMP	MGI:MGI:3690333	Mouse	PMID:23509158
Biological Process	GO:0032528	microvillus organization	Ptpn11	IMP	MGI:MGI:3690333	Mouse	PMID:24675817
Biological Process	GO:0035264	multicellular organism growth	Ptpn11	IMP	MGI:MGI:3690333	Mouse	PMID:24675817
Biological Process	GO:0035264	multicellular organism growth	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0048609	multicellular organismal reproductive process	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0033629	negative regulation of cell adhesion mediated by integrin	Ptpn11	IMP	MGI:MGI:3690333	Mouse	PMID:23509158
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	Ptpn11	IMP		Mouse	MGI:MGI:6414736|PMID:29644115
Biological Process	GO:0051463	negative regulation of cortisol secretion	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0060125	negative regulation of growth hormone secretion	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0046888	negative regulation of hormone secretion	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0046676	negative regulation of insulin secretion	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	ptpn11a	IMP	ZFIN:ZDB-MRPHLNO-101026-4	Zfish	PMID:20493809
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	ptpn11a	IMP		Zfish	PMID:20493809
Biological Process	GO:0032480	negative regulation of type I interferon production	PTPN11	IDA		Human	PMID:26358190
Biological Process	GO:0048011	neurotrophin TRK receptor signaling pathway	Ptpn11	IMP		Mouse	PMID:12482708
Biological Process	GO:0035265	organ growth	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	PTPN11	IMP		Human	PMID:10655584
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	PTPN11	IDA		Human	PMID:15133037
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	PTPN11	IMP		Human	PMID:17562706
Biological Process	GO:0030220	platelet formation	Ptpn11	IGI	MGI:MGI:2146995	Mouse	PMID:23509158
Biological Process	GO:0030220	platelet formation	Ptpn11	IGI	MGI:MGI:96055	Mouse	PMID:23509158
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Ptpn11	IGI	MGI:MGI:87860	Mouse	PMID:18827006
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PTPN11	IMP		Human	PMID:28074573
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Ptpn11	IGI	MGI:MGI:87860	Mouse	PMID:18827006
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Ptpn11	IGI	MGI:MGI:99604	Mouse	PMID:24431450
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	Ptpn11	IMP		Rat	PMID:16905534|RGD:39456088
Biological Process	GO:0046326	positive regulation of glucose import	PTPN11	IDA		Human	PMID:7493946
Biological Process	GO:0046887	positive regulation of hormone secretion	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	PTPN11	IDA		Human	PMID:7493946
Biological Process	GO:0032728	positive regulation of interferon-beta production	Ptpn11	IMP		Mouse	MGI:MGI:3760575|PMID:17954568
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Ptpn11	IGI	UniProtKB:P97797	Mouse	MGI:MGI:3760575|PMID:17954568
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	Ptpn11	IGI	MGI:MGI:97528	Mouse	PMID:18827006
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	Ptpn11	IGI	MGI:MGI:87859	Mouse	PMID:18827006
Biological Process	GO:0045778	positive regulation of ossification	Ptpn11	IMP		Mouse	MGI:MGI:6414736|PMID:29644115
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PTPN11	IMP		Human	PMID:26706435
Biological Process	GO:0009967	positive regulation of signal transduction	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Ptpn11	IGI	UniProtKB:P97797	Mouse	MGI:MGI:3760575|PMID:17954568
Biological Process	GO:0006470	protein dephosphorylation	PTPN11	IMP		Human	PMID:19275884
Biological Process	GO:0006470	protein dephosphorylation	Ptpn11	IDA		Rat	PMID:15272025|RGD:1581313
Biological Process	GO:0006470	protein dephosphorylation	Ptpn11	IDA		Rat	PMID:7711057|RGD:2293185
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	PTPN11	IMP		Human	PMID:10655584
Biological Process	GO:0043408	regulation of MAPK cascade	Ptpn11	IMP	MGI:MGI:3050284	Mouse	PMID:15273746
Biological Process	GO:0043408	regulation of MAPK cascade	Ptpn11	IMP	MGI:MGI:2176524	Mouse	PMID:12937170
Biological Process	GO:0046825	regulation of protein export from nucleus	Ptpn11	IMP	MGI:MGI:2176524	Mouse	PMID:12937170
Biological Process	GO:0043254	regulation of protein-containing complex assembly	PTPN11	IDA		Human	PMID:7493946
Biological Process	GO:0007165	signal transduction	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383
Biological Process	GO:0048659	smooth muscle cell proliferation	Ptpn11	IEP		Rat	PMID:12117720|RGD:39456082
Biological Process	GO:0006641	triglyceride metabolic process	Ptpn11	IMP	MGI:MGI:3522021	Mouse	PMID:15520383

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern