Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPN12
  • Mouse genes Ptpn12
  • Rat genes Ptpn12
  • Zfish genes ptpn12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpn12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	PTPN12	IDA		Human	PMID:27134172
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Ptpn12	IDA		Mouse	PMID:7772023
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:O43586	Human	PMID:11971877
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P09619	Human	PMID:12614164
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P04626	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P09619	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P49023	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:Q02763	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P29353	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P00533	Human	PMID:21376233
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P04626	Human	PMID:21376233
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P09619	Human	PMID:21376233
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P29353	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P29353	Human	PMID:24412244
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P29353	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P49023	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P56945	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P00533	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P29353	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:O43586	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:P56945	Human	PMID:9285683
Molecular Function	GO:0005515	protein binding	PTPN12	IPI	UniProtKB:Q6P5Z4	Human	PMID:9285683
Molecular Function	GO:0005515	protein binding	Ptpn12	IPI	UniProtKB:P97814	Mouse	MGI:MGI:5508289|PMID:11711533
Molecular Function	GO:0005515	protein binding	Ptpn12	IPI	UniProtKB:Q99N69|UniProtKB:Q9QVP9	Mouse	MGI:MGI:5306321|PMID:12674328
Molecular Function	GO:0005515	protein binding	Ptpn12	IPI	UniProtKB:P97814	Mouse	MGI:MGI:1312961|PMID:9804817
Molecular Function	GO:0005515	protein binding	Ptpn12	IPI	UniProtKB:P98083	Mouse	MGI:MGI:5508573|PMID:20075861
Molecular Function	GO:0005515	protein binding	Ptpn12	IPI	UniProtKB:Q99N69	Mouse	MGI:MGI:5306581|PMID:15786712
Molecular Function	GO:0005515	protein binding	Ptpn12	IPI	PR:Q8VI36	Mouse	PMID:14699151
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN12	EXP		Human	PMID:21376233
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn12	IDA		Rat	PMID:7957881|RGD:633766
Molecular Function	GO:0017124	SH3 domain binding	PTPN12	IPI	UniProtKB:P56945	Human	PMID:9285683
Cellular Component	GO:0005829	cytosol	Ptpn12	IDA		Mouse	PMID:7772023
Cellular Component	GO:0002102	podosome	Ptpn12	IDA		Mouse	MGI:MGI:5306321|PMID:12674328
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	PTPN12	IMP		Human	PMID:27134172
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	PTPN12	IDA		Human	PMID:27134172
Biological Process	GO:0006470	protein dephosphorylation	PTPN12	IDA		Human	PMID:27134172
Biological Process	GO:0006470	protein dephosphorylation	Ptpn12	IDA		Mouse	PMID:7772023
Biological Process	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	PTPN12	IMP		Human	PMID:27134172
Biological Process	GO:0042246	tissue regeneration	Ptpn12	IEP		Rat	PMID:7591957|RGD:1599982

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern