Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPN14
  • Mouse genes Ptpn14
  • Rat genes Ptpn14
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpn14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:P46937	Human	PMID:22525271
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:P46937	Human	PMID:22948661
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:P46937	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:P46937	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:P46937	Human	PMID:25283809
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:P46937	Human	PMID:25751139
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:A2BDD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN14	IPI	UniProtKB:Q15654	Human	PMID:32296183
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN14	IMP		Human	PMID:22525271
Molecular Function	GO:0030971	receptor tyrosine kinase binding	PTPN14	IPI	UniProtKB:P35916	Human	PMID:20826270
Molecular Function	GO:0003712	transcription coregulator activity	PTPN14	IMP		Human	PMID:22525271
Cellular Component	GO:0005737	cytoplasm	PTPN14	IDA		Human	PMID:10934049
Cellular Component	GO:0005737	cytoplasm	PTPN14	IDA		Human	PMID:22525271
Cellular Component	GO:0005654	nucleoplasm	PTPN14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PTPN14	IDA		Human	PMID:10934049
Cellular Component	GO:0005634	nucleus	PTPN14	IDA		Human	PMID:22525271
Biological Process	GO:0001946	lymphangiogenesis	PTPN14	IMP		Human	PMID:20826270
Biological Process	GO:0001946	lymphangiogenesis	Ptpn14	IMP		Mouse	MGI:MGI:4939987|PMID:20826270
Biological Process	GO:0008285	negative regulation of cell population proliferation	PTPN14	IMP		Human	PMID:22948661
Biological Process	GO:0046825	regulation of protein export from nucleus	PTPN14	IDA		Human	PMID:22948661

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern