Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPN18
  • Mouse genes Ptpn18
  • Rat genes Ptpn18
  • Zfish genes ptpn18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpn18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	Ptpn18	IDA		Mouse	PMID:8875997
Molecular Function	GO:0005515	protein binding	PTPN18	IPI	UniProtKB:P04626	Human	PMID:25081058
Molecular Function	GO:0005515	protein binding	PTPN18	IPI	UniProtKB:Q9Y297	Human	PMID:25081058
Molecular Function	GO:0005515	protein binding	PTPN18	IPI	UniProtKB:O43586	Human	PMID:9422760
Molecular Function	GO:0005515	protein binding	Ptpn18	IPI	UniProtKB:P97814|UniProtKB:Q99M15	Mouse	MGI:MGI:1312961|PMID:9804817
Molecular Function	GO:0005515	protein binding	Ptpn18	IPI	PR:P97814	Mouse	PMID:9265651
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN18	EXP		Human	PMID:25081058
Cellular Component	GO:0005737	cytoplasm	Ptpn18	IDA		Mouse	PMID:8875997
Cellular Component	GO:0005634	nucleus	Ptpn18	IDA		Mouse	PMID:8875997
Biological Process	GO:0001825	blastocyst formation	Ptpn18	IMP		Mouse	PMID:27869233

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern