Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPN3
  • Mouse genes Ptpn3
  • Rat genes Ptpn3
  • Zfish genes ptpn3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpn3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	PTPN3	IPI	UniProtKB:P55072	Human	PMID:10364224
Molecular Function	GO:0001784	phosphotyrosine residue binding	PTPN3	IPI	UniProtKB:P55072	Human	PMID:10364224
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P55072	Human	PMID:10364224
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P78536	Human	PMID:12207026
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P10912	Human	PMID:12907755
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q14524	Human	PMID:16930557
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P06463	Human	PMID:17947517
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P61981	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P11473	Human	PMID:21119599
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P25800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q04828	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q14689-6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q8TBK6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q9NNW5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q9NPJ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P42566-1	Human	PMID:25728925
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P31946	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P61981	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P63104	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q8TAA9	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P23508	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P31040	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P31946	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P61981	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P63104	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q8TAA9	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q9ULK5	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P61981	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P25800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P40692	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q01664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q04828	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q5GFL6-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q6ZRS2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q8NEK8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q8WV44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q96QG7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:Q9NNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN3	IPI	UniProtKB:P31946	Human	PMID:9341175
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN3	IDA		Human	PMID:19167335
Molecular Function	GO:0017080	sodium channel regulator activity	PTPN3	IDA		Human	PMID:16930557
Cellular Component	GO:0005737	cytoplasm	PTPN3	IDA		Human	PMID:10940933
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	PTPN3	IDA		Human	PMID:10940933
Biological Process	GO:0097421	liver regeneration	Ptpn3	IEP		Rat	PMID:7591957|RGD:1599982
Biological Process	GO:0051045	negative regulation of membrane protein ectodomain proteolysis	PTPN3	IMP		Human	PMID:12207026
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	PTPN3	IDA		Human	PMID:10364224
Biological Process	GO:0006470	protein dephosphorylation	PTPN3	IDA		Human	PMID:10364224
Biological Process	GO:0098902	regulation of membrane depolarization during action potential	PTPN3	IDA		Human	PMID:16930557
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	PTPN3	IDA		Human	PMID:16930557

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern