Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPRD
  • Mouse genes Ptprd
  • Rat genes Ptprd
  • Zfish genes ptprdb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptprd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	Ptprd	IPI	UniProtKB:P0C192	Mouse	MGI:MGI:5294265|PMID:21940441
Molecular Function	GO:0005515	protein binding	PTPRD	IPI	UniProtKB:O43312	Human	PMID:12570871
Molecular Function	GO:0005515	protein binding	PTPRD	IPI	UniProtKB:O14965	Human	PMID:22305495
Molecular Function	GO:0005515	protein binding	Ptprd	IPI	UniProtKB:P59823	Mouse	MGI:MGI:5294265|PMID:21940441
Molecular Function	GO:0005515	protein binding	Ptprd	IPI	UniProtKB:P59823|UniProtKB:Q61730	Mouse	MGI:MGI:5645611|PMID:25908590
Molecular Function	GO:0005515	protein binding	Ptprd	IPI	UniProtKB:Q9NZN1	Mouse	MGI:MGI:5294265|PMID:21940441
Molecular Function	GO:0005515	protein binding	Ptprd	IPI	UniProtKB:Q810B8|UniProtKB:Q810C0	Mouse	MGI:MGI:5902672|PMID:25989451
Molecular Function	GO:0005515	protein binding	Ptprd	IPI	PR:Q810B9	Mouse	PMID:29107521
Molecular Function	GO:0005102	signaling receptor binding	Ptprd	IPI	UniProtKB:P59823	Mouse	MGI:MGI:5294265|PMID:21940441
Cellular Component	GO:0070062	extracellular exosome	PTPRD	HDA		Human	PMID:23533145
Cellular Component	GO:0098978	glutamatergic synapse	PTPRD	IDA		Human	PMID:21926414
Cellular Component	GO:0098978	glutamatergic synapse	PTPRD	IMP		Human	PMID:21926414
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	IMP		Mouse	PMID:22357843
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	IDA		Mouse	PMID:22357843
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	IPI		Mouse	PMID:22357843
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	IDA		Mouse	PMID:29024665
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	IMP		Mouse	PMID:32347567
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	IDA		Mouse	PMID:32347567
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	EXP		Rat	PMID:29024665|RGD:13702141
Cellular Component	GO:0098978	glutamatergic synapse	Ptprd	IDA		Rat	PMID:29024665|RGD:13702141
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Ptprd	IDA		Mouse	PMID:10856223
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Ptprd	IMP		Mouse	PMID:10856223
Cellular Component	GO:0042734	presynaptic membrane	Ptprd	IDA		Mouse	PMID:29024665
Cellular Component	GO:0042734	presynaptic membrane	Ptprd	IDA		Mouse	PMID:32347567
Cellular Component	GO:0042734	presynaptic membrane	Ptprd	IMP		Mouse	PMID:32347567
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ptprd	IDA		Mouse	PMID:10856223
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ptprd	IMP		Mouse	PMID:10856223
Cellular Component	GO:0045202	synapse	Ptprd	IDA		Mouse	MGI:MGI:6441563|PMID:32347567
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Ptprd	IDA		Mouse	MGI:MGI:5294265|PMID:21940441
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ptprd	IDA		Mouse	PMID:10856223
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ptprd	IMP		Mouse	PMID:10856223
Biological Process	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	Ptprd	IMP	MGI:MGI:2158795	Mouse	PMID:24843164
Biological Process	GO:0030182	neuron differentiation	Ptprd	IDA		Mouse	MGI:MGI:5294265|PMID:21940441
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Ptprd	IDA		Mouse	MGI:MGI:5294265|PMID:21940441
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Ptprd	IMP		Mouse	MGI:MGI:5294265|PMID:21940441
Biological Process	GO:0051965	positive regulation of synapse assembly	Ptprd	IDA		Mouse	MGI:MGI:5645611|PMID:25908590
Biological Process	GO:0051965	positive regulation of synapse assembly	Ptprd	IDA		Mouse	MGI:MGI:5902672|PMID:25989451
Biological Process	GO:0099054	presynapse assembly	PTPRD	IDA		Human	PMID:21926414
Biological Process	GO:0099054	presynapse assembly	PTPRD	IMP		Human	PMID:21926414
Biological Process	GO:0097105	presynaptic membrane assembly	Ptprd	IMP		Mouse	MGI:MGI:5294265|PMID:21940441
Biological Process	GO:0097105	presynaptic membrane assembly	Ptprd	IDA		Mouse	MGI:MGI:5294265|PMID:21940441
Biological Process	GO:0050776	regulation of immune response	Ptprd	IMP	MGI:MGI:2158795	Mouse	PMID:24843164
Biological Process	GO:0099151	regulation of postsynaptic density assembly	Ptprd	IPI		Mouse	PMID:22357843
Biological Process	GO:0099151	regulation of postsynaptic density assembly	Ptprd	IDA		Mouse	PMID:22357843
Biological Process	GO:0099151	regulation of postsynaptic density assembly	Ptprd	IMP		Mouse	PMID:22357843
Biological Process	GO:0099151	regulation of postsynaptic density assembly	Ptprd	EXP		Rat	PMID:29024665|RGD:13702141
Biological Process	GO:0099151	regulation of postsynaptic density assembly	Ptprd	IDA		Rat	PMID:29024665|RGD:13702141
Biological Process	GO:0099560	synaptic membrane adhesion	PTPRD	IDA		Human	PMID:23345436
Biological Process	GO:0099560	synaptic membrane adhesion	PTPRD	IMP		Human	PMID:23345436
Biological Process	GO:0099560	synaptic membrane adhesion	Ptprd	IDA		Rat	PMID:20139422|RGD:13702345
Biological Process	GO:0099560	synaptic membrane adhesion	Ptprd	IMP		Rat	PMID:20139422|RGD:13702345
Biological Process	GO:0099560	synaptic membrane adhesion	Ptprd	IDA		Rat	PMID:27225731|RGD:13702436
Biological Process	GO:0099560	synaptic membrane adhesion	Ptprd	IMP		Rat	PMID:27225731|RGD:13702436
Biological Process	GO:0099537	trans-synaptic signaling	Ptprd	IDA		Mouse	PMID:32347567
Biological Process	GO:0099537	trans-synaptic signaling	Ptprd	IEP		Mouse	PMID:32347567
Biological Process	GO:0099537	trans-synaptic signaling	Ptprd	IMP		Mouse	PMID:32347567
Biological Process	GO:0099545	trans-synaptic signaling by trans-synaptic complex	PTPRD	IDA		Human	PMID:21926414
Biological Process	GO:0099545	trans-synaptic signaling by trans-synaptic complex	PTPRD	IMP		Human	PMID:21926414

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern