Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPRM
  • Mouse genes Ptprm
  • Rat genes Ptprm
  • Zfish genes si:ch1073-391i24.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptprm

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	PTPRM	IDA		Human	PMID:9531566
Molecular Function	GO:0042802	identical protein binding	PTPRM	IPI	UniProtKB:P28827	Human	PMID:10809770
Molecular Function	GO:0016791	phosphatase activity	PTPRM	IDA		Human	PMID:10753936
Molecular Function	GO:0005515	protein binding	PTPRM	IPI	UniProtKB:P63244	Human	PMID:11278757
Molecular Function	GO:0005515	protein binding	PTPRM	IPI	UniProtKB:P46940	Human	PMID:16380380
Molecular Function	GO:0005515	protein binding	PTPRM	IPI	UniProtKB:P09803	Human	PMID:9531566
Molecular Function	GO:0005515	protein binding	Ptprm	IPI	UniProtKB:Q62470	Mouse	MGI:MGI:6294221|PMID:14691142
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPRM	IDA		Human	PMID:17965016
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPRM	IDA		Human	PMID:18566238
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPRM	IDA		Human	PMID:8393854
Molecular Function	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	PTPRM	IDA		Human	PMID:10809770
Cellular Component	GO:0005912	adherens junction	PTPRM	IDA		Human	PMID:17965016
Cellular Component	GO:0005911	cell-cell junction	PTPRM	IDA		Human	PMID:10753936
Cellular Component	GO:0005911	cell-cell junction	PTPRM	IDA		Human	PMID:15491993
Cellular Component	GO:0005911	cell-cell junction	PTPRM	IDA		Human	PMID:16380380
Cellular Component	GO:0005737	cytoplasm	PTPRM	IDA		Human	PMID:16380380
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	PTPRM	IDA		Human	PMID:17761881
Cellular Component	GO:0030027	lamellipodium	PTPRM	IDA		Human	PMID:15706045
Cellular Component	GO:0048471	perinuclear region of cytoplasm	PTPRM	IDA		Human	PMID:15491993
Cellular Component	GO:0005886	plasma membrane	PTPRM	IDA		Human	GO_REF:0000052
Biological Process	GO:0051220	cytoplasmic sequestering of protein	PTPRM	IDA		Human	PMID:10753936
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	PTPRM	IDA		Human	PMID:8393854
Biological Process	GO:0016525	negative regulation of angiogenesis	PTPRM	IMP		Human	PMID:18566238
Biological Process	GO:0010596	negative regulation of endothelial cell migration	PTPRM	IMP		Human	PMID:18566238
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	PTPRM	IMP		Human	PMID:18566238
Biological Process	GO:0031175	neuron projection development	PTPRM	IDA		Human	PMID:16380380
Biological Process	GO:0031175	neuron projection development	PTPRM	IMP		Human	PMID:17276081
Biological Process	GO:0006470	protein dephosphorylation	PTPRM	IDA		Human	PMID:10809770
Biological Process	GO:0006470	protein dephosphorylation	PTPRM	IDA		Human	PMID:8393854
Biological Process	GO:0009410	response to xenobiotic stimulus	PTPRM	IDA		Human	PMID:18566238
Biological Process	GO:0010842	retina layer formation	PTPRM	IMP		Human	PMID:14623235
Biological Process	GO:0031290	retinal ganglion cell axon guidance	PTPRM	IDA		Human	PMID:15080886
Biological Process	GO:0007165	signal transduction	PTPRM	IDA		Human	PMID:15080886
Biological Process	GO:0042311	vasodilation	Ptprm	IMP	MGI:MGI:3575002	Mouse	PMID:15706045

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern